Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Daniela Zdzieblo"'
Autor:
Constantin Berger, Markus Glaser, Anna-Lena Ziegler, Valentina Neukel, Fabiola Walz, Daniela Zdzieblo
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Stem cell-derived β-cells (SC-BCs) represent a potential source for curing diabetes. To date, in vitro generated SC-BCs display an immature phenotype and lack important features in comparison to their bona-fide counterparts. Transplantation
Externí odkaz:
https://doaj.org/article/542c96a67f2b4d67aa93e991f934bd3c
Autor:
Christina Fey, Theresa Truschel, Kristina Nehlsen, Spyridon Damigos, Julia Horstmann, Theresia Stradal, Tobias May, Marco Metzger, Daniela Zdzieblo
Publikováno v:
Journal of Tissue Engineering, Vol 15 (2024)
Two-dimensional culture remains widely employed to determine the bioavailability of orally delivered drugs. To gain more knowledge about drug uptake mechanisms and risk assessment for the patient after oral drug admission, intestinal in vitro models
Externí odkaz:
https://doaj.org/article/58dff52e794b458dbac3988ef02461c2
Autor:
Thomas Däullary, Fabian Imdahl, Oliver Dietrich, Laura Hepp, Tobias Krammer, Christina Fey, Winfried Neuhaus, Marco Metzger, Jörg Vogel, Alexander J. Westermann, Antoine-Emmanuel Saliba, Daniela Zdzieblo
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTInfection research largely relies on classical cell culture or mouse models. Despite having delivered invaluable insights into host-pathogen interactions, both have limitations in translating mechanistic principles to human pathologies. Alter
Externí odkaz:
https://doaj.org/article/4e6314defbf542fa8797bca5587d5316
Autor:
Ivo Schwedhelm, Daniela Zdzieblo, Antje Appelt-Menzel, Constantin Berger, Tobias Schmitz, Bernhard Schuldt, Andre Franke, Franz-Josef Müller, Ole Pless, Thomas Schwarz, Philipp Wiedemann, Heike Walles, Jan Hansmann
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/62e4f06d5edf49d2b653200aee21bbcd
Autor:
Lorea Zubiaga, Olivier Briand, Florent Auger, Veronique Touche, Thomas Hubert, Julien Thevenet, Camille Marciniak, Audrey Quenon, Caroline Bonner, Simon Peschard, Violeta Raverdy, Mehdi Daoudi, Julie Kerr-Conte, Gianni Pasquetti, Hermann Koepsell, Daniela Zdzieblo, Markus Mühlemann, Bernard Thorens, Nathalie D. Delzenne, Laure B. Bindels, Benoit Deprez, Marie C. Vantyghem, Blandine Laferrère, Bart Staels, Damien Huglo, Sophie Lestavel, François Pattou
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106057- (2023)
Summary: Metformin (MET) is the most prescribed antidiabetic drug, but its mechanisms of action remain elusive. Recent data point to the gut as MET’s primary target. Here, we explored the effect of MET on the gut glucose transport machinery. Using
Externí odkaz:
https://doaj.org/article/a2d8b736d8cd49a09e2f84d1fd3fac11
Autor:
Markus Mühlemann, Daniela Zdzieblo, Alexandra Friedrich, Constantin Berger, Christoph Otto, Heike Walles, Hermann Koepsell, Marco Metzger
Publikováno v:
Molecular Metabolism, Vol 13, Iss , Pp 67-76 (2018)
Objectives: Glycemic control by medical treatment represents one therapeutic strategy for diabetic patients. The Na+-d-glucose cotransporter 1 (SGLT1) is currently of high interest in this context. SGLT1 is known to mediate glucose absorption and inc
Externí odkaz:
https://doaj.org/article/159e06ca7c5c4a7b811839201b52e2f4
Autor:
Elisa Monzon-Casanova, Birte Steiniger, Stefanie Schweigle, Holger Clemen, Daniela Zdzieblo, Lisa Starick, Ingrid Müller, Chyung-Ru Wang, Sara Rhost, Susanna Cardell, Elwira Pyz, Thomas Herrmann
Publikováno v:
PLoS ONE, Vol 5, Iss 9 (2010)
CD1d is a nonpolymorphic MHC class I-like molecule which presents nonpeptide ligands, e.g. glycolipids, to NKT cells. These cells are known to have multiple effects on innate and adaptive immune responses and on the development of pathological condit
Externí odkaz:
https://doaj.org/article/edfd5180012744dd853e8c5794e12b17
Autor:
Iola F. Duarte, Sofia Dembski, Patricia M. A. Farias, Despina Fragouli, Winfried Neuhaus, Andreas Brachner, Manosij Ghosh, Jeroen Vanoirbeek, Daniela Zdzieblo, Ivan Barišić, Philipp Schwabl
Publikováno v:
International Journal of Environmental Research and Public Health, Vol 17, Iss 8832, p 8832 (2020)
International Journal of Environmental Research and Public Health
International Journal of Environmental Research and Public Health
The exposure of humans to nano-and microplastic particles (NMPs) is an issue recognized as a potential health hazard by scientists, authorities, politics, non-governmental organizations and the general public. The concentration of NMPs in the environ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f42c3241d0765597b6b38bb86c875908
https://lirias.kuleuven.be/handle/123456789/668519
https://lirias.kuleuven.be/handle/123456789/668519
Autor:
Daniela Zdzieblo, Constantin Berger
Publikováno v:
Pflugers Archiv
The fine-tuning of glucose uptake mechanisms is rendered by various glucose transporters with distinct transport characteristics. In the pancreatic islet, facilitative diffusion glucose transporters (GLUTs), and sodium-glucose cotransporters (SGLTs)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01bf8a36fccb284fc9f293b53ea42ce6
https://publica.fraunhofer.de/handle/publica/263026
https://publica.fraunhofer.de/handle/publica/263026
This chapter describes state-of-the-art of small intestinal tissue engineering. It starts with an introduction to architecture and function of the small intestine. It further provides an overview of current tissue engineering approaches such as organ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16598f7af0c77afbad23ed33bd31901d
https://doi.org/10.1016/b978-0-08-102906-0.00025-8
https://doi.org/10.1016/b978-0-08-102906-0.00025-8