Výsledky vyhledávání - "Daniela Wolpers"

Enhanced Glucose Tolerance by SK4 Channel Inhibition in Pancreatic β-Cells

Autor: Daniela Wolpers, Martina Düfer, Peter Krippeit-Drews, Gisela Drews, Peter Ruth, Belinda Gier

Publikováno v: Diabetes

OBJECTIVE Ca2+-regulated K+ channels are involved in numerous Ca2+-dependent signaling pathways. In this study, we investigated whether the Ca2+-activated K+ channel of intermediate conductance SK4 (KCa3.1, IK1) plays a physiological role in pancreat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::702409cfc1d1644f8245672f39240112
http://europepmc.org/articles/PMC2712794

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Reduced rather than enhanced cholinergic airway constriction in mice with ablation of the large conductance Ca2+‐activated K+channel

Autor: Stefan Uhlig, Daniela Wolpers, Thomas Gudermann, Peter Ruth, Franz Hofmann, Xiaobo Zhou, Winfried Neuhuber, Harald Renz, Anna-Rebekka Ressmeyer, Ulrike Sausbier, Christian Martin, Michael Korth, Jens Schlossmann, Matthias Sausbier, Caroline Beier, Sylvi Maget, Alexander Dietrich

Publikováno v: The FASEB Journal. 21:812-822

The unique voltage- and Ca2+-dependent K+ (BK) channel, prominently expressed in airway smooth muscle cells, has been suggested as an important effector in controlling airway contractility. Its deletion in mice depolarized resting membrane potential

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a17f2f6bec7dc851f26ad065dfc88d4c
https://doi.org/10.1096/fj.06-7167com

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