Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Daniela Welcker"'
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Akademický článek
Hemicentin-1 is an essential extracellular matrix component of the dermal–epidermal and myotendinous junctions
Autor: Daniela Welcker, Cornelia Stein, Natalia Martins Feitosa, Joy Armistead, Jin-Li Zhang, Steffen Lütke, Andre Kleinridders, Jens C. Brüning, Sabine A. Eming, Gerhard Sengle, Anja Niehoff, Wilhelm Bloch, Matthias Hammerschmidt
Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract The extracellular matrix architecture is composed of supramolecular fibrillar networks that define tissue specific cellular microenvironments. Hemicentins (Hmcn1 and Hmcn2) are ancient and very large members (> 600 kDa) of the fibulin family
Externí odkaz: https://doaj.org/article/96f15bdd865a41c29b23c156bb4759bc
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3
Supplementary Figures from ATM Deficiency Is Associated with Sensitivity to PARP1- and ATR Inhibitors in Lung Adenocarcinoma
Autor: Hans Christian Reinhardt, Martin Peifer, Sven Perner, Reinhard Büttner, Uschi Leeser, Michael Nowak, Julie George, Tsun-Po Yang, Daniela Welcker, Gero Knittel, Anna Schmitt
In this file we show additional data which support the main findings in our manuscript, e.g. an overview of all immunofluorescent and histological images, population doubling of the cell lines used, additional in vivo data on etoposide and cisplatin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::844cf0a2ae24aff91729d8e34537cdaf
https://doi.org/10.1158/0008-5472.22413809
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4
Data from ATM Deficiency Is Associated with Sensitivity to PARP1- and ATR Inhibitors in Lung Adenocarcinoma
Autor: Hans Christian Reinhardt, Martin Peifer, Sven Perner, Reinhard Büttner, Uschi Leeser, Michael Nowak, Julie George, Tsun-Po Yang, Daniela Welcker, Gero Knittel, Anna Schmitt
Defects in maintaining genome integrity are a hallmark of cancer. The DNA damage response kinase ATM is frequently mutated in human cancer, but the significance of these events to chemotherapeutic efficacy has not been examined deeply in whole organi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3e508a861e54342bc7ffdfa9b2ae0562
https://doi.org/10.1158/0008-5472.c.6508823.v1
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6
Hemicentin-1 is an essential extracellular matrix component of the dermal–epidermal and myotendinous junctions
Autor: Anja Niehoff, Jin-Li Zhang, Wilhelm Bloch, Matthias Hammerschmidt, Joy Armistead, Natália Martins Feitosa, Sabine A. Eming, Cornelia Stein, André Kleinridders, Steffen Lütke, Daniela Welcker, Gerhard Sengle, Jens C. Brüning
Publikováno v: Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
The extracellular matrix architecture is composed of supramolecular fibrillar networks that define tissue specific cellular microenvironments. Hemicentins (Hmcn1 and Hmcn2) are ancient and very large members (> 600 kDa) of the fibulin family, whose s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e70d8265661f17966bbe68a326092089
http://europepmc.org/articles/PMC8429575
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7
ATM Deficiency Is Associated with Sensitivity to PARP1- and ATR Inhibitors in Lung Adenocarcinoma
Autor: U. Leeser, Martin Peifer, Tsun-Po Yang, Reinhard Büttner, Sven Perner, Daniela Welcker, Michael Nowak, Anna Schmitt, Gero Knittel, Hans Christian Reinhardt, Julie George
Publikováno v: Cancer Research. 77:3040-3056
Defects in maintaining genome integrity are a hallmark of cancer. The DNA damage response kinase ATM is frequently mutated in human cancer, but the significance of these events to chemotherapeutic efficacy has not been examined deeply in whole organi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c82b2dfb9df2a924641ff3ee680640ed
https://doi.org/10.1158/0008-5472.can-16-3398
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9
AATF suppresses apoptosis, promotes proliferation and is critical for Kras-driven lung cancer
Autor: Maurizio Fanciulli, Mladen Jokic, Katja Höpker, Anna Schmitt, Reinhard Büttner, Bernhard Schermer, Safiya Khurshid, Carien M. Niessen, Maike Wittersheim, Judith Eva Spiro, Martin Höhne, Daniela Welcker, Thorsten Persigehl, Hans Christian Reinhardt, Peter Frommolt, Thomas Benzing, Manaswita Jain
Publikováno v: Oncogene. 37(11)
A fundamental principle in malignant tranformation is the ability of cancer cells to escape the naturally occurring cell-intrinsic responses to DNA damage. Tumors progress despite the accumulation of DNA lesions. However, the underlying mechanisms of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc866030c9d6eb0f94f6a172fd16e82f
https://pubmed.ncbi.nlm.nih.gov/29321668
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