Výsledky vyhledávání - "Daniela Vogl"

Intracellular Polyamine Levels of Intestinal Epithelial Cells in Inflammatory Bowel Disease

Autor: Daniela Vogl, J. Ouart, Gerhard Rogler, J. Schölmerich, Hans H Herfarth, Florian Obermeier, K.-W. Jauch, Thomas S. Weiss

Publikováno v: Inflammatory Bowel Diseases. 10:529-535

Polyamines and their acetylated derivatives are a prerequisite for cellular metabolism and considered to be essential for proliferation and differentiation of the rapidly renewing intestinal mucosa. However, their role during mucosal inflammation is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a273eaf5b1746219e3896b56e51181c3
https://doi.org/10.1097/00054725-200409000-00006

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Reduced migration of fibroblasts in inflammatory bowel disease: role of inflammatory mediators and focal adhesion kinase1 1The authors thank Dr. Luitpold E. Miller for his assistance in the preparation of this manuscript; the doctors and nurses of the Endoscopy department; the surgeons and pathologists of the University of Regensburg, especially Dr. Frauke Bataille, for their ongoing great cooperation; and, most importantly, all patients who agreed to give biopsy and tissue samples, without whom this study would not have been possible

Autor: Stephan Kiessling, Cornelia M. Gelbmann, Manuela Gunckel, Daniela Vogl, Gerhard Rogler, Jürgen Schölmerich, Werner Falk, Sandra N. Leeb, Michael Göke

Publikováno v: Gastroenterology. 125:1341-1354

Background & Aims: Crohn's disease (CD) and ulcerative colitis (UC) are associated with chronic tissue damage and continuous tissue repair. A central, but not well-characterized, event during this process is the migration of activated fibroblasts to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::caa75ebf4369ca7cab64b4baa12e8cdd
https://doi.org/10.1016/j.gastro.2003.07.004

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Inducible CD40 expression mediates NF B activation and cytokine secretion in human colonic fibroblasts

Autor: Werner Falk, Hans H Herfarth, Sandra N. Leeb, J. Schölmerich, Cornelia M. Gelbmann, Daniela Vogl, M. Maendel, Gerhard Rogler

Publikováno v: Gut. 52:1448-1456

Background: CD40 has been shown to be a functional activation antigen on a variety of cell types involved in immune responses. As intestinal fibroblasts and myofibroblasts may play a role during mucosal inflammation, we investigated the functional co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f2589c7fec6cf7edc93cbdcd14099ee
https://doi.org/10.1136/gut.52.10.1448

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Differential Activation of Cytokine Secretion in Primary Human Colonic Fibroblast/Myofibroblast Cultures

Autor: J. Schölmerich, Gerhard Rogler, K Brand, Cornelia M. Gelbmann, M Brunner, Tilo Andus, Daniela Vogl, Werner Falk

Publikováno v: Scandinavian Journal of Gastroenterology. 36:389-398

Fibroblasts and myofibroblasts are known to secrete a wide spectrum of cytokines, but the individual spectrum is tissue-specific. We investigated the effect of cell activation on cytokine secretion of isolated human colonic fibroblasts/myofibroblasts

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9b9b1c7412df41c03c2901d3bb349ca
https://doi.org/10.1080/003655201300051216

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T-cell co-stimulatory molecules are upregulated on intestinal macrophages from inflammatory bowel disease mucosa

Autor: E. Aschenbrenner, Gerhard Rogler, Jürgen Schölmerich, Volker Gross, T. Spöttl, Martin Hausmann, Werner Falk, Tilo Andus, Daniela Vogl

Publikováno v: European Journal of Gastroenterology & Hepatology. 11:1105-1112

Background and aims Macrophages play an important role during mucosal inflammation in inflammatory bowel disease (IBD). As the co-stimulatory molecules B7-1 (CD80) and B7-2 (CD86) play an integral role in the activation of T cells by antigen-presenti

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https://doi.org/10.1097/00042737-199910000-00006

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Isolation and phenotypic characterization of colonic macrophages

Autor: Martin Hausmann, Reinhard Andreesen, Gerhard Rogler, V. Gross, Daniela Vogl, E. Aschenbrenner, Jürgen Schölmerich, Werner Falk, T. Andus

Publikováno v: Clinical and Experimental Immunology. 112:205-215

SUMMARY Macrophages play an important role in the intestinal mucosal immune system. However, they are a poorly defined cell population. We therefore determined their phenotype in normal colonic mucosa. Macrophages were isolated from colonic biopsies

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https://doi.org/10.1046/j.1365-2249.1998.00557.x

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Alterations of the phenotype of colonic macrophages in inflammatory bowel disease

Autor: Gerhard Rogler, Jürgen Schölmerich, Werner Falk, Volker Gross, Tilo Andus, E. Aschenbrenner, Daniela Vogl

Publikováno v: European Journal of Gastroenterology & Hepatology. 9:893-899

Intestinal macrophages play an important role in mucosal inflammation. In normal colonic mucosa we recently demonstrated a unique macrophage phenotype with attenuated immune functions. Here we present an analysis of the alterations of the phenotype o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41c48814c0108a0560be158cc075f7eb
https://doi.org/10.1097/00042737-199709000-00013

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13-Oxo-ODE is an endogenous ligand for PPARgamma in human colonic epithelial cells

Autor: K. Menzel, Martin Hausmann, Daniela Vogl, Hans H Herfarth, Gerhard Rogler, Werner Falk, Arthur W. Bull, Michael Gruber, T. Spöttl, Jürgen Schölmerich, Reinhold Altmann

Publikováno v: Biochemical pharmacology. 74(4)

Background The ligand activated nuclear hormone receptor peroxisome proliferator-activated receptor gamma (PPARγ) induces transcriptional repression of pro-inflammatory factors. Activation of PPARγ is followed by amelioration of colitis in animal m

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https://pubmed.ncbi.nlm.nih.gov/17604003

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Autocrine fibronectin-induced migration of human colonic fibroblasts

Autor: Johannes Grossmann, Saudra N Leeb, Werner Falk, Gerhard Rogler, J. Schölmerich, Cornelia M. Gelbmann, Daniela Vogl

Publikováno v: The American journal of gastroenterology. 99(2)

OBJECTIVES A central event during wound repair is the migration of activated fibroblasts to the wound area. Thus far, the mechanisms inducing migration of colonic lamina propria fibroblasts (CLPF) have not been studied in detail. Previously, we have

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fae62f00238862f7f8863df2f52b22ec
https://pubmed.ncbi.nlm.nih.gov/15046226

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