Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Daniela Virgintino"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Externí odkaz:
https://doaj.org/article/256f2a7fc0e0432eb7257e20dce73820
Autor:
Mariella Errede, Tiziana Annese, Valentina Petrosino, Giovanna Longo, Francesco Girolamo, Ignazio de Trizio, Antonio d’Amati, Antonio Uccelli, Nicole Kerlero de Rosbo, Daniela Virgintino
Publikováno v:
Fluids and Barriers of the CNS, Vol 19, Iss 1, Pp 1-25 (2022)
Abstract Background In myelin oligodendrocyte glycoprotein (MOG)-induced experimental autoimmune encephalomyelitis (EAE), several areas of demyelination are detectable in mouse cerebral cortex, where neuroinflammation events are associated with scarc
Externí odkaz:
https://doaj.org/article/b14b931f4de7414d962d612c7471b1e3
Autor:
Mariangela Mastrapasqua, Roberta Rossi, Lucrezia De Cosmo, Annalisa Resta, Mariella Errede, Antonella Bizzoca, Stefania Zampatti, Nicoletta Resta, Emiliano Giardina, Maddalena Ruggieri, Daniela Virgintino, Tiziana Annese, Nicola Laforgia, Francesco Girolamo
Publikováno v:
European Journal of Translational Myology (2023)
The autophagy process recycles dysfunctional cellular components and protein aggregates by sequestering them in autophagosomes directed to lysosomes for enzymatic degradation. A basal level of autophagy is essential for skeletal muscle maintenance. I
Externí odkaz:
https://doaj.org/article/011e2bb5c32444f9a2e04e529fb2b10a
Autor:
Marc Schwab, Ignazio de Trizio, Moheb Ghobrial, Jau-Ye Shiu, Oguzkan Sürücü, Francesco Girolamo, Mariella Errede, Murat Yilmaz, Johannes Haybaeck, Alessandro Moiraghi, Philippe P. Monnier, Sean E. Lawler, Jeffrey P. Greenfield, Ivan Radovanovic, Karl Frei, Ralph Schlapbach, Viola Vogel, Daniela Virgintino, Katrien De Bock, Thomas Wälchli
Publikováno v:
JCI Insight, Vol 8, Iss 8 (2023)
Glioblastomas are among the deadliest human cancers and are highly vascularized. Angiogenesis is dynamic during brain development, almost quiescent in the adult brain but reactivated in vascular-dependent CNS pathologies, including brain tumors. The
Externí odkaz:
https://doaj.org/article/3c686c5575aa4c10bf181a463b9ada86
Autor:
Francesco Girolamo, Ignazio de Trizio, Mariella Errede, Giovanna Longo, Antonio d’Amati, Daniela Virgintino
Publikováno v:
Fluids and Barriers of the CNS, Vol 18, Iss 1, Pp 1-26 (2021)
Abstract Central nervous system diseases involving the parenchymal microvessels are frequently associated with a ‘microvasculopathy’, which includes different levels of neurovascular unit (NVU) dysfunction, including blood–brain barrier alterat
Externí odkaz:
https://doaj.org/article/1bde4cf505784ecea40649b4d178d328
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6743 (2023)
Microvasculature develops during early brain development. Hypoxia–ischemia (HI) and hypoxia (H) predispose to brain injury in neonates. Inter-alpha inhibitor proteins (IAIPs) attenuate injury to the neonatal brain after exposure to HI. However, the
Externí odkaz:
https://doaj.org/article/ef460339b4a94610af8fae85b131d2db
Autor:
Yiran Liu, David Castano, Francesco Girolamo, Laia Trigueros-Motos, Han-Gyu Bae, Suat Peng Neo, Jeongah Oh, Pradeep Narayanaswamy, Federico Torta, Kerry Anne Rye, Dong-Gyu Jo, Jayantha Gunaratne, Sangyong Jung, Daniela Virgintino, Roshni R. Singaraja
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 1, Pp 100147- (2022)
The myelin sheath, which is wrapped around axons, is a lipid-enriched structure produced by mature oligodendrocytes. Disruption of the myelin sheath is observed in several neurological diseases, such as multiple sclerosis. A crucial component of myel
Externí odkaz:
https://doaj.org/article/622ddf4efa064a70bc8d47a1a10e6767
Publikováno v:
Cells, Vol 11, Iss 10, p 1707 (2022)
Successful neuroprotection is only possible with contemporary microvascular protection. The prevention of disease-induced vascular modifications that accelerate brain damage remains largely elusive. An improved understanding of pericyte (PC) signalli
Externí odkaz:
https://doaj.org/article/5e4df8d37a004396b140a5c9340bde5f
Autor:
Kazuki Hatayama, Sydney Riddick, Fares Awa, Xiaodi Chen, Daniela Virgintino, Barbara S. Stonestreet
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 8, p 4180 (2022)
Exposure to hypoxic-ischemic (HI) insults in newborns can predispose them to severe neurological sequela. The mechanisms underlying HI-related brain injury have not been completely elucidated. The neurovascular unit (NVU) is a composite of structures
Externí odkaz:
https://doaj.org/article/19de665d70f74b449fd8063eb6f4bb6e
Autor:
Carolina Pellegrini, Chiara Ippolito, Cristina Segnani, Amelio Dolfi, Mariella Errede, Daniela Virgintino, Matteo Fornai, Luca Antonioli, Francesca Garelli, Anna Nericcio, Rocchina Colucci, Silvia Cerri, Fabio Blandini, Corrado Blandizzi, Nunzia Bernardini
Publikováno v:
Neurobiology of Disease, Vol 139, Iss , Pp 104821- (2020)
Background and aim: Patients with Parkinson's disease (PD) are often characterized by functional gastrointestinal disorders. Such disturbances can occur at all stages of PD and precede the typical motor symptoms of the disease by many years. However,
Externí odkaz:
https://doaj.org/article/a771361a7b97466e9bb1a0667b2300f6