Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Daniela Vasilescu"'
Autor:
Katherine Bonter, Eustache Paramithiotis, Heather Butler, Paul Kearney, Joanna M. Hunter, Patrice Hugo, Kossi Lekpor, Daniel Chelsky, Gregory J. Opiteck, Marie-Josée Benoit, Daniela Vasilescu, Michael Schirm
Publikováno v:
PROTEOMICS – Clinical Applications. 1:457-466
Multidimensional fingerprinting (MDF) utilizes measurable peptide characteristics to identify proteins. In this study, 3-D fingerprinting, namely, parent protein molecular weight, peptide mass, and peptide retention time on RPLC, is used to identify
Autor:
Brian Leyland-Jones, De Marte J, A. Mustafa, Bertrand J. Jean-Claude, Z. Damian, Daniela Vasilescu, Tak Hang Chan, Rose Yen
Publikováno v:
Cancer Chemotherapy and Pharmacology. 42:59-67
Cytotoxicity, reduction of macromolecule synthesis and cell cycle perturbations by two novel 3-(2-chloroethyl)-tetrazepinones, PYRCL and QUINCL were compared with those produced by the structurally related 3-(2-chloroethyl)-tetrazinone, mitozolomide,
Autor:
A. Mustafa, Bertrand J. Jean-Claude, Z. Damian, J. De Marte, Rose Yen, N. D. Cetateanu, Daniela Vasilescu, Tak Hang Chan, Brian Leyland-Jones
Publikováno v:
British Journal of Cancer
The mechanism of action of the novel heterocycle 3,5-dimethyl-pyrido-1,2,3,5-tetrazepin-4-one (PYRZ), structurally related to temozolomide, was studied in the human ovarian tumour cell line OVCAR-3. Our results showed that, despite its marked structu
Publikováno v:
ChemInform. 32
In order to confer water solubility to the benzotetrazepinone ring system, the synthesis of 12 was undertaken. The design and synthesis of 12 were based upon previously established structural requirements for the stability of the 1,2,3,5-tetrazepin-4
Publikováno v:
Bioorganicmedicinal chemistry letters. 10(20)
In order to confer water solubility to the benzotetrazepinone ring system, the synthesis of 12 was undertaken. The design and synthesis of 12 were based upon previously established structural requirements for the stability of the 1,2,3,5-tetrazepin-4
Autor:
S Damian, Daniela Vasilescu, Elias Georges, Bertrand J. Jean-Claude, G Batist, Lawrence Panasci, A. Mustafa, Brian Leyland-Jones, Z. Damian, Zhi Liu
Publikováno v:
Biochemical pharmacology. 52(7)
Acquired drug resistance is a major factor in the failure of doxorubicin-based chemotherapy in breast cancer. We determined the ability of megestrol acetate and/or tamoxifen to reverse doxorubicin drug resistance in a doxorubicin-resistant breast can