Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Daniela Svetlovska"'
Autor:
Michal Mego, Barbora Kasperova, Jozef Chovanec, Radoslav Danis, Maria Reckova, Branislav Bystricky, Peter Konkolovsky, Silvia Jurisova, Stefan Porsok, Vladimir Vaclav, Maria Wagnerova, Marian Stresko, Bibiana Brezinova, Dagmar Sutekova, Sona Ciernikova, Daniela Svetlovska, Lubos Drgona
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundProbiotics could decrease irinotecan-induced diarrhea due to the reduction of intestinal beta-d-glucuronidase activity. This study included a combined analysis of two clinical trials aimed to determine the effectiveness of the probiotics in
Externí odkaz:
https://doaj.org/article/a354ee21b09e4bb193c6e70534c8595d
Autor:
Michal Mego, Radoslav Danis, Jozef Chovanec, Silvia Jurisova, Branislav Bystricky, Stefan Porsok, Peter Konkolovsky, Vladimir Vaclav, Maria Wagnerova, Marian Streško, Bibiana Brezinova, Mária Rečková, Dagmar Sutekova, Natalia Pazderova, Mária Novisedlakova, Eva Zomborska, Sona Ciernikova, Daniela Svetlovska, Lubos Drgona
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundThe incidence of irinotecan-induced diarrhea varies between 60-90%, by which the incidence of severe diarrhea is 20-40%. The objective of this phase III trial was to determine the effectiveness of the probiotic mixture containing Bifidobact
Externí odkaz:
https://doaj.org/article/90f3d7448e0b418f9c9713fc6d2328e5
Autor:
Michal Chovanec, Katarina Kalavska, Jana Obertova, Patrik Palacka, Katarina Rejlekova, Zuzana Sycova-Mila, Zuzana Orszaghova, Peter Lesko, Valentina De Angelis, Lucia Vasilkova, Daniela Svetlovska, Beata Mladosievicova, Jozef Mardiak, Michal Pastorek, Barbora Vlkova, Peter Celec, Michal Mego
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundSurvivors of testicular germ cell tumors (GCT) may suffer from late cognitive impairment. We hypothesized that disruption of intestinal barrier during chemotherapy and/or radiotherapy may be a contributing factor of cognitive dysfunction wi
Externí odkaz:
https://doaj.org/article/abf7e03270314533aff2dabde227fda2
Autor:
Michal Mego, Katarina Rejlekova, Daniela Svetlovska, Vera Miskovska, Ad J.M. Gillis, Valentina De Angelis, Katarina Kalavska, Jana Obertova, Patrik Palacka, Maria Reckova, Zuzana Sycova-Mila, Daniel Pindak, Michal Chovanec, Leendert H.J. Looijenga, Jozef Mardiak
Publikováno v:
European Urology Open Science, Vol 33, Iss , Pp 19-27 (2021)
Background: Germ cell tumors represent highly curable disease even in metastatic stage. However, poor-risk patients with an unfavorable serum tumor marker (STM) decline after the first cycle of chemotherapy represent a subgroup with dismal prognosis,
Externí odkaz:
https://doaj.org/article/d3c43bc015da42a092dcf78191b04e22
Autor:
Katarina Kalavska, Zuzana Sestakova, Andrea Mlcakova, Paulina Gronesova, Viera Miskovska, Katarina Rejlekova, Daniela Svetlovska, Zuzana Sycova-Mila, Jana Obertova, Patrik Palacka, Jozef Mardiak, Miroslav Chovanec, Michal Chovanec, Michal Mego
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The pattern of immune cell distribution in testicular germ cell tumors (GCT) significantly differs from the immune environment in normal testicular tissues. The present study aimed to evaluate the role of different leukocyte subpopulation in GCTs. A
Externí odkaz:
https://doaj.org/article/9c04b63fe92a4f1993d3dd27de6da4ca
Autor:
Zuzana Cierna, Vera Miskovska, Jan Roska, Dana Jurkovicova, Lucia Borszekova Pulzova, Zuzana Sestakova, Lenka Hurbanova, Katarina Machalekova, Michal Chovanec, Katarina Rejlekova, Daniela Svetlovska, Katarina Kalavska, Karol Kajo, Pavel Babal, Jozef Mardiak, Thomas A. Ward, Michal Mego, Miroslav Chovanec
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-12 (2020)
Abstract Background Germ cell tumours (GCTs) represent a highly curable malignity as they respond well to cisplatin (CDDP)-based chemotherapy. Nevertheless, a small proportion of GCT patients relapse or do not respond to therapy. As this might be cau
Externí odkaz:
https://doaj.org/article/a1198c34116345488384869795332127
Autor:
Katarina Kalavska, Zuzana Sestakova, Andrea Mlcakova, Paulina Gronesova, Viera Miskovska, Katarina Rejlekova, Daniela Svetlovska, Zuzana Sycova-Mila, Jana Obertova, Patrik Palacka, Jozef Mardiak, Miroslav Chovanec, Michal Chovanec, Michal Mego
Publikováno v:
Life, Vol 12, Iss 5, p 678 (2022)
The tumor microenvironment (TME) and the host inflammatory response are closely interconnected. The interplay between systemic inflammation and the local immune response may influence tumor development and progression in various types of cancer. The
Externí odkaz:
https://doaj.org/article/367ab3bb9108473ea0b1e0d0af88d0de
Autor:
Michal Chovanec, Zuzana Cierna, Viera Miskovska, Katarina Machalekova, Katarina Kalavska, Katarina Rejlekova, Daniela Svetlovska, Dusan Macak, Stanislav Spanik, Karol Kajo, Pavel Babal, Michal Mego, Jozef Mardiak
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background WNT/βcatenin (WNTβ) pathway is activated in early stages of embryonic development. We aimed to evaluate the significance of βcatenin in germ cell tumors (GCTs) and explore associations with the inflamed environment. Methods Sur
Externí odkaz:
https://doaj.org/article/e2bedfd776a24a93b149c36fc239cb18
Autor:
Jan Slopovsky, Jarmila Kucharska, Jana Obertova, Michal Mego, Katarina Kalavska, Silvia Cingelova, Daniela Svetlovska, Anna Gvozdjakova, Samuel Furka, Patrik Palacka
Publikováno v:
Translational Oncology, Vol 14, Iss 1, Pp 100890- (2021)
Oxidative stress plays a significant role in development and progression of cancer, including urothelial carcinomas. TBARS (Thiobarbituric acid reactive substances) represents a marker of oxidative stress increased in various diseases. In this prospe
Externí odkaz:
https://doaj.org/article/f830145c5c7b4059810bf36ea757603a
Autor:
Katarina Kalavska, Zuzana Sestakova, Andrea Mlcakova, Katarína Kozics, Paulina Gronesova, Lenka Hurbanova, Viera Miskovska, Katarina Rejlekova, Daniela Svetlovska, Zuzana Sycova-Mila, Jana Obertova, Patrik Palacka, Jozef Mardiak, Michal Chovanec, Miroslav Chovanec, Michal Mego
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 15, p 8281 (2021)
Chemoresistance of germ cell tumors (GCTs) represents an intensively studied property of GCTs that is the result of a complicated multifactorial process. One of the driving factors in this process is the tumor microenvironment (TME). Intensive crosst
Externí odkaz:
https://doaj.org/article/4e18b719e71b480d83d331ee7f5d6a5e