Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Daniela Stork"'
Autor:
Manfred Auer, Steffen Hering, Stanislav Berjukow, Annette Hohaus, Daniela Stork, Evgeny Timin, Clemens Huber
Publikováno v:
British Journal of Pharmacology. 151:1368-1376
Background and purpose: Inhibition of HERG channels prolongs the ventricular action potential and the QT interval with the risk of torsade de pointes arrhythmias and sudden cardiac death. Many drugs induce greater inhibition of HERG channels when the
Autor:
Eugen Timin, Khac-Minh Thai, Andrea Schiesaro, A. Windisch, Anna Weinzinger, Daniela Stork, Steffen Hering, Robert H. Guy, Gerhard F. Ecker
Publikováno v:
ChemMedChem. 5(3)
The inner cavity of the hERG potassium ion channel can accommodate large, structurally diverse compounds that can be trapped in the channel by closure of the activation gate. A small set of propafenone derivatives was synthesized, and both use-depend
Autor:
Annette Hohaus, Daniela Stork, A. Windisch, Steffen Hering, Manfred Auer, Gerhard F. Ecker, Evgeny Timin
Publikováno v:
BMC Pharmacology. 7(Suppl 2):A13