Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Daniela Stauffer"'
Autor:
Giulio Morozzi, Julian Rothen, Gauthier Toussaint, Katrina De Lange, Katrin Westritschnig, Arno Doelemeyer, Vanessa Pitiot Ueberschlag, Peter Kahle, Christian Lambert, Michael Obrecht, Nicolau Beckmann, Veronique Ritter, Moh Panesar, Daniela Stauffer, Isabelle Garnier, Matthias Mueller, Danilo Guerini, Caroline Gubser Keller, Judith Knehr, Guglielmo Roma, Michael Bidinosti, Sophie Brachat, Frederic Morvan, Mara Fornaro
Publikováno v:
iScience, Vol 24, Iss 12, Pp 103434- (2021)
Summary: Inflammatory responses are crucial for regeneration following peripheral nerve injury (PNI). PNI triggers inflammatory responses at the site of injury. The DNA-sensing receptor cyclic GMP-AMP synthase (cGAS) and its downstream effector stimu
Externí odkaz:
https://doaj.org/article/34f8e9f03cac483cb7ab6b1f71128e9e
Autor:
Martin C Herzig, Michael Bidinosti, Tatjana Schweizer, Thomas Hafner, Christine Stemmelen, Andreas Weiss, Simone Danner, Nella Vidotto, Daniela Stauffer, Carmen Barske, Franziska Mayer, Peter Schmid, Giorgio Rovelli, P Herman van der Putten, Derya R Shimshek
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36581 (2012)
The G2019S mutation in the multidomain protein leucine-rich repeat kinase 2 (LRRK2) is one of the most frequently identified genetic causes of Parkinson's disease (PD). Clinically, LRRK2(G2019S) carriers with PD and idiopathic PD patients have a very
Externí odkaz:
https://doaj.org/article/91e76d844a7f47b8b87909b246097341
Autor:
Sophie Brachat, Danilo Guerini, Nicolau Beckmann, Isabelle Garnier, Veronique Ritter, Vanessa Pitiot Ueberschlag, Daniela Stauffer, Giulio Morozzi, Frederic Morvan, Katrin Westritschnig, Gauthier Toussaint, Julian Rothen, Judith Knehr, Michael Obrecht, Peter Kahle, Michael Bidinosti, Mara Fornaro, Matthias Mueller, Arno Doelemeyer, Katrina De Lange, Caroline Gubser Keller, Moh Panesar, Christian Lambert, Guglielmo Roma
Publikováno v:
iScience
iScience, Vol 24, Iss 12, Pp 103434-(2021)
iScience, Vol 24, Iss 12, Pp 103434-(2021)
Summary Inflammatory responses are crucial for regeneration following peripheral nerve injury (PNI). PNI triggers inflammatory responses at the site of injury. The DNA-sensing receptor cyclic GMP-AMP synthase (cGAS) and its downstream effector stimul
Autor:
Christina Dornelas, Sabine Gutzwiller, Serge Summermatter, Erin Nolin, David J. Glass, Eliane Pierrel, Christy Fryer, Juliet Leighton-Davies, Stefan Melly, Daniela Stauffer, Brigitte Fournier, Anais Bouzan
Publikováno v:
Molecular and Cellular Biology. 37
Metallothioneins are proteins that are involved in intracellular zinc storage and transport. Their expression levels have been reported to be elevated in several settings of skeletal muscle atrophy. We therefore investigated the effect of metallothio
Autor:
Stefan F. Lichtenthaler, Bruno Martoglio, Elena Friedmann, Kerstin Maylandt, Daniela Stauffer, Sarah Vreugde, Giorgio Rovelli, Simone Schleeger, Peer-Hendrik Kuhn, Ehud Hauben
Publikováno v:
Nature Cell Biology. 8:843-848
Homologues of signal peptide peptidase (SPPLs) are putative aspartic proteases that may catalyse regulated intramembrane proteolysis of type II membrane-anchored signalling factors. Here, we show that four human SPPLs are each sorted to a different c
Publikováno v:
Microscopy Research and Technique. 66:275-288
Embryonic development is associated with extensive vascular growth and remodeling. We used immunohistochemical, light and electron microscopical techniques, as well as vascular casting methods to study the developing chick embryo kidney with special
Autor:
Kumlesh K. Dev, Daniela Stauffer, Natalie Finney, Fabienne Walther, Giorgio Rovelli, Pierre-Yves Mantel
Publikováno v:
Journal of Biological Chemistry. 278:16054-16058
Parkin is a ubiquitin-protein isopeptide ligase (E3) involved in ubiquitin/proteasome-mediated protein degradation. Mutations in the parkin gene cause a loss-of-function and/or alter protein levels of parkin. As a result, the toxic build-up of parkin
Autor:
Klemens Kaupmann, Tewis Bouwmeester, Marc Meyer, Sjouke Hoving, Lionel Muller, Petranka Krumova, Lauran Reyniers, Bertran Gerrits, Giorgio Rovelli, Johannes Voshol, Doriano Fabbro, Andreas Bauer, Jean-Marc Taymans, Veerle Baekelandt, Evy Lobbestael, Daniela Stauffer
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 29(7)
Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common cause of autosomal-dominant forms of Parkinson's disease. LRRK2 is a modular, multidomain protein containing 2 enzymatic domains, including a kinase domain, as well as several prot
Autor:
Jean-Philippe Pin, Isabelle Brabet, Daniela Stauffer, Thierry Fischer, Jaroslav Blahos, Giorgio Rovelli, Joël Bockaert
Publikováno v:
Journal of Biological Chemistry. 276:3262-3269
Specific domains of the G-protein alpha subunit have been shown to control coupling to heptahelical receptors. The extreme N and C termini and a region between alpha4 and alpha5 helices of the G-protein alpha subunit are known to determine selective
Autor:
Karen Huebscher, Beat Ludin, Peter Fürst, Giorgio Rovelli, Daniela Stauffer, Janet Lee, Andrew Matus
Publikováno v:
Gene. 240:333-341
Protein L-isoaspartyl methyltransferase (Pimt) is a highly conserved enzyme utilising S-adenosylmethionine (AdoMet) to methylate aspartate residues of proteins damaged by age-related isomerisation and deamidation. We have been particularly interested