Depression in patients with mastocytosis: prevalence, features and effects of masitinib therapy.

Autor: Daniela Silva Moura, Serge Sultan, Sophie Georgin-Lavialle, Nathalie Pillet, François Montestruc, Paul Gineste, Stéphane Barete, Gandhi Damaj, Alain Moussy, Olivier Lortholary, Olivier Hermine

Publikováno v: PLoS ONE, Vol 6, Iss 10, p e26375 (2011)

Depression in patients with mastocytosis is often reported but its prevalence and characteristics are not precisely described. In addition, the impact of therapies targeting mast cells proliferation, differentiation and degranulation on psychic sympt

Externí odkaz: https://doaj.org/article/f04c1496e096403089243bc06b6ecabc

Decreased tryptophan and increased kynurenine levels in mastocytosis associated with digestive symptoms

Autor: Jean-Marie Launay, Angèle Soria, Olivier Hermine, Francine Côté, Sophie Georgin-Lavialle, Marie-Olivia Chandesris, Stéphane Barete, Erinn Soucie, Gandhi Damaj, Patrice Dubreuil, Katia Hanssens, Harry Sokol, Olivier Lortholary, Danielle Canioni, Daniela Silva Moura

Publikováno v: Allergy
Allergy, Wiley, 2016, 71 (3), pp.416-420. 〈10.1111/all.12802〉
Allergy, 2016, 71 (3), pp.416-420. ⟨10.1111/all.12802⟩
Allergy, Wiley, 2016, 71 (3), pp.416-420. ⟨10.1111/all.12802⟩

International audience; The main metabolism pathway of tryptophan is protein formation, but it can also be metabolized into serotonin and kynurenine. Indoleamine 2,3-dioxygenase (IDO) is the enzyme that catalyzes the degradation of tryptophan into ky

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fda71c2b3e68bb8f1c5b6bddc29f24e1
https://hal.archives-ouvertes.fr/hal-01269697

Neuropsychological features of adult mastocytosis

Autor: Daniela Silva Moura, Raphaël Gaillard, Olivier Hermine, Sophie Georgin-Lavialle

Publikováno v: Immunology and allergy clinics of North America. 34(2)

In approximately one-third of cases, patients with mastocytosis can display various disabling general and neuropsychological symptoms. General signs may have a major impact on quality of life. Neurologic symptoms are less frequent. In a majority of c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a3d5142f02d57aafab4a5a4c0e7c80e
https://pubmed.ncbi.nlm.nih.gov/24745683

Evidence for cognitive impairment in mastocytosis: prevalence, features and correlations to depression

Autor: Sophie Georgin-Lavialle, Olivier Hermine, Olivier Lortholary, Serge Sultan, Daniela Silva Moura, Stéphane Barete, Raphaël Gaillard

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2012, 7, pp.e39468-e-39474
PLoS ONE, Vol 7, Iss 6, p e39468 (2012)

Mastocytosis is a heterogeneous disease characterized by mast cells accumulation in one or more organs. We have reported that depression is frequent in mastocytosis, but although it was already described, little is known about the prevalence and feat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f576bbc117c7a12686636512501dd093
https://hal.archives-ouvertes.fr/hal-00740406