Zobrazeno 1 - 10 of 81 pro vyhledávání: '"Daniela Schilling"'
1
Akademický článek
In-vivo X-ray dark-field computed tomography for the detection of radiation-induced lung damage in mice
Autor: Rico Burkhardt, Thomas Gora, Alexander A. Fingerle, Andreas P. Sauter, Felix Meurer, Florian T. Gassert, Sophie Dobiasch, Daniela Schilling, Annette Feuchtinger, Axel K. Walch, Gabriele Multhoff, Julia Herzen, Peter B. Noël, Ernst J. Rummeny, Stephanie E. Combs, Thomas E. Schmid, Franz Pfeiffer, Jan J. Wilkens
Publikováno v: Physics and Imaging in Radiation Oncology, Vol 20, Iss , Pp 11-16 (2021)
Background and Purpose: Radiotherapy of thoracic tumours can lead to side effects in the lung, which may benefit from early diagnosis. We investigated the potential of X-ray dark-field computed tomography by a proof-of-principle murine study in a cli
Externí odkaz: https://doaj.org/article/c4e136775c6a440cb16e1a91eb7e3ace
Zobrazit plný text záznamu
3
Akademický článek
Lomeguatrib Increases the Radiosensitivity of MGMT Unmethylated Human Glioblastoma Multiforme Cell Lines
Autor: Anna Kirstein, Daniela Schilling, Stephanie E. Combs, Thomas E. Schmid
Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 13, p 6781 (2021)
Background: Treatment resistance of glioblastoma multiforme to chemo- and radiotherapy remains a challenge yet to overcome. In particular, the O6-methylguanine-DNA-methyltransferase (MGMT) promoter unmethylated patients have only little benefit from
Externí odkaz: https://doaj.org/article/ef605e0737bf4ecc83033f0e70998450
Zobrazit plný text záznamu
4
Akademický článek
Cytosolic Hsp70 as a biomarker to predict clinical outcome in patients with glioblastoma.
Autor: Friederike Lämmer, Claire Delbridge, Silvia Würstle, Frauke Neff, Bernhard Meyer, Jürgen Schlegel, Kerstin A Kessel, Thomas E Schmid, Daniela Schilling, Stephanie E Combs
Publikováno v: PLoS ONE, Vol 14, Iss 8, p e0221502 (2019)
IntroductionThe major stress-inducible heat shock protein 70 (Hsp70) is induced after different stress stimuli. In tumors, elevated intracellular Hsp70 levels were associated on the one hand with radio- and chemotherapy resistance and on the other ha
Externí odkaz: https://doaj.org/article/3b85f7c5e0904aeab3980d599d68b82e
Zobrazit plný text záznamu
5
Akademický článek
Radiosensitization of HSF-1 Knockdown Lung Cancer Cells by Low Concentrations of Hsp90 Inhibitor NVP-AUY922
Autor: Annett Kühnel, Daniela Schilling, Stephanie E. Combs, Bernhard Haller, Melissa Schwab, Gabriele Multhoff
Publikováno v: Cells, Vol 8, Iss 10, p 1166 (2019)
The inhibition of heat shock protein 90 (Hsp90) a molecular chaperone for multiple oncogenic client proteins is considered as a promising approach to overcome radioresistance. Since most Hsp90 inhibitors activate HSF-1 that induces the transcription
Externí odkaz: https://doaj.org/article/a46d48aa413f476e82f88d960c9af4a8
Zobrazit plný text záznamu
6
Akademický článek
Dependence of intracellular and exosomal microRNAs on viral E6/E7 oncogene expression in HPV-positive tumor cells.
Autor: Anja Honegger, Daniela Schilling, Sandra Bastian, Jasmin Sponagel, Vladimir Kuryshev, Holger Sültmann, Martin Scheffner, Karin Hoppe-Seyler, Felix Hoppe-Seyler
Publikováno v: PLoS Pathogens, Vol 11, Iss 3, p e1004712 (2015)
Specific types of human papillomaviruses (HPVs) cause cervical cancer. Cervical cancers exhibit aberrant cellular microRNA (miRNA) expression patterns. By genome-wide analyses, we investigate whether the intracellular and exosomal miRNA compositions
Externí odkaz: https://doaj.org/article/f648690e2b8b46809671dbf3ed7de015
Zobrazit plný text záznamu
7
Akademický článek
Radiosensitization of normoxic and hypoxic h1339 lung tumor cells by heat shock protein 90 inhibition is independent of hypoxia inducible factor-1α.
Autor: Daniela Schilling, Christine Bayer, Wei Li, Michael Molls, Peter Vaupel, Gabriele Multhoff
Publikováno v: PLoS ONE, Vol 7, Iss 2, p e31110 (2012)
Ionizing irradiation is a commonly accepted treatment modality for lung cancer patients. However, the clinical outcome is hampered by normal tissue toxicity and tumor hypoxia. Since tumors often have higher levels of active heat shock protein 90 (Hsp
Externí odkaz: https://doaj.org/article/a92976f874f44b8b99bacd5c4810a3c2
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje