Zobrazeno 1 - 10
of 286
pro vyhledávání: '"Daniela Salvemini"'
Autor:
Rocco Mollace, Federica Scarano, Irene Bava, Cristina Carresi, Jessica Maiuolo, Annamaria Tavernese, Micaela Gliozzi, Vincenzo Musolino, Saverio Muscoli, Ernesto Palma, Carolina Muscoli, Daniela Salvemini, Massimo Federici, Roberta Macrì, Vincenzo Mollace
Publikováno v:
Pharmacological Research, Vol 196, Iss , Pp 106931- (2023)
Evidence exists that heart failure (HF) has an overall impact of 1–2 % in the global population being often associated with comorbidities that contribute to increased disease prevalence, hospitalization, and mortality. Recent advances in pharmacolo
Externí odkaz:
https://doaj.org/article/d443551ad7ba4b588bdbe83e3bd06ff7
Autor:
Anand Kumar Singh, Rajasekaran Mahalingam, Silvia Squillace, Kenneth A. Jacobson, Dilip K. Tosh, Shruti Dharmaraj, Susan A. Farr, Annemieke Kavelaars, Daniela Salvemini, Cobi J. Heijnen
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-17 (2022)
Abstract Cisplatin is used to combat solid tumors. However, patients treated with cisplatin often develop cognitive impairments, sensorimotor deficits, and peripheral neuropathy. There is no FDA-approved treatment for these neurotoxicities. We invest
Externí odkaz:
https://doaj.org/article/5b44d6910ee840eebed105fd78d879a2
Autor:
Silvia Squillace, Michael L. Niehoff, Timothy M. Doyle, Michael Green, Emanuela Esposito, Salvatore Cuzzocrea, Christopher K. Arnatt, Sarah Spiegel, Susan A. Farr, Daniela Salvemini
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 17 (2022)
Cancer-related cognitive impairment (CRCI) is a major neurotoxicity affecting more than 50% of cancer survivors. The underpinning mechanisms are mostly unknown, and there are no FDA-approved interventions. Sphingolipidomic analysis of mouse prefronta
Externí odkaz:
https://doaj.org/article/1997f1a57945403ea08d3af60277e069
Autor:
Susan A. Farr, Salvatore Cuzzocrea, Emanuela Esposito, Michela Campolo, Michael L. Niehoff, Timothy M. Doyle, Daniela Salvemini
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-14 (2020)
Abstract Background Traumatic brain injury (TBI) is a common pathological condition that presently lacks a specific pharmacological treatment. Adenosine levels rise following TBI, which is thought to be neuroprotective against secondary brain injury.
Externí odkaz:
https://doaj.org/article/0af6ca2da5904eb890fffdc4fb84dcce
Autor:
Timothy M. Doyle, Mark R. Hutchinson, Kathryn Braden, Kali Janes, Vicky Staikopoulos, Zhoumou Chen, William L. Neumann, Sarah Spiegel, Daniela Salvemini
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-8 (2020)
Abstract Opioid therapies for chronic pain are undermined by many adverse side effects that reduce their efficacy and lead to dependence, abuse, reduced quality of life, and even death. We have recently reported that sphingosine-1-phosphate (S1P) 1 r
Externí odkaz:
https://doaj.org/article/aa30603a92e14637a5ad0de991f3f7b6
Publikováno v:
Neurobiology of Pain, Vol 11, Iss , Pp 100082- (2022)
Treatment with anti-neoplastic agents can lead to the development of chemotherapy induced peripheral neuropathy (CIPN), which is long lasting and often refractory to treatment. This neuropathic pain develops along dermatomes innervated by peripheral
Externí odkaz:
https://doaj.org/article/2020feed51ec423cbdbdc910a9bd74dd
Autor:
Jessica Maiuolo, Rocco Mollace, Francesca Bosco, Federica Scarano, Francesca Oppedisano, Saverio Nucera, Stefano Ruga, Lorenza Guarnieri, Roberta Macri, Irene Bava, Cristina Carresi, Micaela Gliozzi, Vincenzo Musolino, Antonio Cardamone, Anna Rita Coppoletta, Andrea Barillaro, Virginia Simari, Daniela Salvemini, Ernesto Palma, Vincenzo Mollace
Publikováno v:
Agriculture, Vol 13, Iss 2, p 249 (2023)
Non-alcoholic fatty liver disease (NAFLD) is considered one of the leading causes of liver-related morbidity and mortality. NAFLD is a cluster of liver disorders that includes the accumulation of fat in the liver, insulin resistance, diffuse steatosi
Externí odkaz:
https://doaj.org/article/a5f3f5cb502548b6931f18440218258d
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/d47d1f9baeef495aaa06a0633d878fc8
Autor:
Aidan Levine, Erika Liktor-Busa, Kelly L. Karlage, Luigi Giancotti, Daniela Salvemini, Todd W. Vanderah, Tally M. Largent-Milnes
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
Recent findings suggested that Clinical Endocannabinoid Deficiency underlies the pathophysiology of pain disorders, including migraine and headache. In models of medication overuse headache induced by sustained administration of sumatriptan or morphi
Externí odkaz:
https://doaj.org/article/c43d97d31e734b1686ee5d26daf30cf0
Autor:
Sara Ilari, Filomena Lauro, Luigino Antonio Giancotti, Valentina Malafoglia, Concetta Dagostino, Micaela Gliozzi, Antonia Condemi, Jessica Maiuolo, Francesca Oppedisano, Ernesto Palma, Carlo Tomino, Daniela Salvemini, Vincenzo Mollace, Carolina Muscoli
Publikováno v:
Pharmaceuticals, Vol 14, Iss 10, p 975 (2021)
Paclitaxel is a chemotherapeutic drug used for cancer treatment. Chemotherapy-induced peripheral neuropathy (CIPN) is a common major dose-limiting side effect of many chemotherapeutic agents, including paclitaxel. CIPN is accompanied by mechanical an
Externí odkaz:
https://doaj.org/article/a9c05762715243a18482705647dd9bfb