Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Daniela Reinisch"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Tremendous advancements in cell and protein engineering methodologies and bioinformatics have led to a vast increase in bacterial production clones and recombinant protein variants to be screened and evaluated. Consequently, an urgent need e
Externí odkaz:
https://doaj.org/article/2638648bdcb948bb8400c8e1cfce7a31
Autor:
Artur Schuller, Monika Cserjan-Puschmann, Christopher Tauer, Johanna Jarmer, Martin Wagenknecht, Daniela Reinisch, Reingard Grabherr, Gerald Striedner
Publikováno v:
Microbial Cell Factories, Vol 19, Iss 1, Pp 1-11 (2020)
Abstract Background The genome-integrated T7 expression system offers significant advantages, in terms of productivity and product quality, even when expressing the gene of interest (GOI) from a single copy. Compared to plasmid-based expression syste
Externí odkaz:
https://doaj.org/article/eb1513b2d7e6473eb3c723ba2d796013
Publikováno v:
Bioengineering, Vol 7, Iss 1, p 8 (2020)
Recombinant production of pharmaceutical proteins like antigen binding fragments (Fabs) in the commonly-used production host Escherichia coli presents several challenges. The predominantly-used plasmid-based expression systems exhibit the drawback of
Externí odkaz:
https://doaj.org/article/c5fadc8f429d4d01887162ab7014fbd5
Autor:
Thomas Zahel, Lukas Marschall, Sandra Abad, Elena Vasilieva, Daniel Maurer, Eric M. Mueller, Patrick Murphy, Thomas Natschläger, Cécile Brocard, Daniela Reinisch, Patrick Sagmeister, Christoph Herwig
Publikováno v:
Bioengineering, Vol 4, Iss 4, p 85 (2017)
Identification of critical process parameters that impact product quality is a central task during regulatory requested process validation. Commonly, this is done via design of experiments and identification of parameters significantly impacting prod
Externí odkaz:
https://doaj.org/article/19ab6136bcc94d38a02bb6cf6e23a182
Autor:
Thomas Zahel, Stefan Hauer, Eric M. Mueller, Patrick Murphy, Sandra Abad, Elena Vasilieva, Daniel Maurer, Cécile Brocard, Daniela Reinisch, Patrick Sagmeister, Christoph Herwig
Publikováno v:
Bioengineering, Vol 4, Iss 4, p 86 (2017)
During the regulatory requested process validation of pharmaceutical manufacturing processes, companies aim to identify, control, and continuously monitor process variation and its impact on critical quality attributes (CQAs) of the final product. It
Externí odkaz:
https://doaj.org/article/7e452616fe0a468198de14e2e684137d
Autor:
Daniela Reinisch, Rainer Hahn, Monika Cserjan-Puschmann, Gerald Striedner, Mathias Fink, Cécile Brocard, Clemens Schimek
Bioprocess development and optimization is a challenging, costly, and time-consuming effort. In this multidisciplinary task, upstream processing (USP) and downstream processing (DSP) are conventionally considered distinct disciplines. This considerat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::56f0b043bf386ac66f41874158facc0d
https://doi.org/10.22541/au.160506182.23416943/v1
https://doi.org/10.22541/au.160506182.23416943/v1
Autor:
Gerald Striedner, Christopher Tauer, Daniela Reinisch, Johanna Jarmer, Monika Cserjan-Puschmann, Artur Schuller, Reingard Grabherr, Martin Wagenknecht
Publikováno v:
Microbial Cell Factories
Microbial Cell Factories, Vol 19, Iss 1, Pp 1-11 (2020)
Microbial Cell Factories, Vol 19, Iss 1, Pp 1-11 (2020)
Background The genome-integrated T7 expression system offers significant advantages, in terms of productivity and product quality, even when expressing the gene of interest (GOI) from a single copy. Compared to plasmid-based expression systems, this
Publikováno v:
Eng Life Sci
Miniaturization and automation have become increasingly popular in bioprocess development in recent years, enabling rapid high-throughput screening and optimization of process conditions. In addition, advances in the bioprocessing industry have led t
Autor:
Gerald Striedner, Mathias Fink, Clemens Schimek, Monika Cserjan-Puschmann, Cécile Brocard, Daniela Reinisch, Rainer Hahn
Publikováno v:
Biotechnology Journal. 16:2000562
Bioprocess development and optimization is a challenging, costly, and time-consuming effort. In this multidisciplinary task, upstream processing (USP) and downstream processing (DSP) are conventionally considered distinct disciplines. This considerat
Autor:
Daniel Maurer, Christoph Herwig, Elena Vasilieva, Stefan Hauer, Eric M. Mueller, Patrick Murphy, Daniela Reinisch, Sandra Abad, Thomas Zahel, Cécile Brocard, Patrick Sagmeister
Publikováno v:
Bioengineering
Bioengineering, Vol 4, Iss 4, p 86 (2017)
Bioengineering; Volume 4; Issue 4; Pages: 86
Bioengineering, Vol 4, Iss 4, p 86 (2017)
Bioengineering; Volume 4; Issue 4; Pages: 86
During the regulatory requested process validation of pharmaceutical manufacturing processes, companies aim to identify, control, and continuously monitor process variation and its impact on critical quality attributes (CQAs) of the final product. It