Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Daniela Regensburger"'
Autor:
Anika Klingler, Daniela Regensburger, Clara Tenkerian, Nathalie Britzen-Laurent, Arndt Hartmann, Michael Stürzl, Elisabeth Naschberger
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0233422 (2020)
SPARCL1 is a matricellular protein with anti-adhesive, anti-proliferative and anti-tumorigenic functions and is frequently downregulated in tumors such as colorectal carcinoma or non-small cell lung cancer. Studies have identified SPARCL1 as an angio
Externí odkaz:
https://doaj.org/article/8656f5f33f234144987437f7409ff0b7
Autor:
Carol Geppert, Rocío López-Posadas, Andreas Ramming, Clara Tenkerian, Heinrich Sticht, Elisabeth Naschberger, Victoria Pürzer, Claudia Günther, Katja Petter, Tim Thoenissen, Christoph Becker, Benjamin Schmid, Thomas Wohlfahrt, Tobias Gass, Valerie Meniel, Christian Flierl, Maximilian J. Waldner, Nathalie Britzen-Laurent, Iris Stolzer, Michael Stürzl, Daniela Regensburger
Publikováno v:
Inflammatory Bowel Diseases
Background The understanding of vascular plasticity is key to defining the role of blood vessels in physiologic and pathogenic processes. In the present study, the impact of the vascular quiescence marker SPARCL1 on angiogenesis, capillary morphogene
Autor:
Michael Stürzl, Daniela Regensburger, Thomas Wohlfahrt, Viktoria Kramer, Noo Li Jeon, Eugenia Vivi, Somin Lee, Victoria Langer, Nathalie Britzen-Laurent, Lisa Skottke, Christoph Becker, Timo Rath, Ralf H. Adams, Karina Suchowski, Andreas Ramming, Benjamin Schmid, Philipp Tripal, Elisabeth Naschberger, Stephan Kersting, Carol Geppert, Claudia Handtrack, Michael Schumann, Thomas Winkler, Maximilian J. Waldner
Publikováno v:
Journal of Clinical Investigation. 129:4691-4707
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder with rising incidence. Diseased tissues are heavily vascularized. Surprisingly, the pathogenic impact of the vasculature in IBD and the underlying regulatory mechanisms remain largel
Autor:
Melanie Langheinrich, Arndt Hartmann, Elisabeth Naschberger, Clara Tenkerian, Felix B. Engel, Robert Grützmann, Michael Stürzl, Daniela Regensburger, Carol Geppert, Vera Schellerer
Publikováno v:
Journal of visualized experiments : JoVE. (134)
Primary cells isolated from human carcinomas are valuable tools to identify pathogenic mechanisms contributing to disease development and progression. In particular, endothelial cells (EC) constituting the inner surface of vessels, directly participa
Autor:
Thomas Wohlfahrt, Andreas Ramming, Clara Tenkerian, Anne Borau, Victoria Langer, Heinrich Sticht, Benjamin Schmid, Robert Grützmann, Elisabeth Naschberger, Vera Schellerer, Nathalie Britzen-Laurent, Anika Klingler, Valerie Meniel, Michael Stürzl, Daniela Regensburger
Publikováno v:
Cancer Research. 79:195-195
Colorectal carcinoma (CRC) is the second leading cause of cancer-related mortality worldwide. The contribution of the tumor microenvironment (TME) to CRC pathogenesis is well established, whereby the dominance of one immune response (Th1) over anothe
Autor:
Michael Stürzl, Daniela Regensburger, Carol-Immanuel Geppert, Valerie Meniel, Victoria Langer, Robert Grützmann, Elisabeth Naschberger, Annika Klingler, Nathalie Britzen-Laurent, Maximilian J. Waldner, Christoph Becker, Clara Tenkerian
Publikováno v:
Cancer Research. 78:2048-2048
In colorectal carcinoma (CRC), a Th1-tumor microenvironment (TME) is associated with improved prognosis of the patients. The lead cytokine of the Th1-response is interferon (IFN)-γ. IFN-γ is predominantly regarded as an immunomodulatory cytokine. A
Autor:
Susanne Merkel, Nathalie Britzen-Laurent, Michael Stürzl, Daniela Regensburger, Tilman T. Rau, Alan Richard Clarke, Vera Schellerer, Patrick Kölbel, Lisa Haep, Elisabeth Naschberger, Ute Schaal, Thomas Wittmann, Barbara Dietel, Werner Hohenberger, Roland S. Croner, Andrea Liebl, Ludger Klein-Hitpass, Valerie Meniel, Manuela Schütz
Publikováno v:
Naschberger, E.; Liebl, A.; Schellerer, V. S.; Schutz, M.; Britzen-Laurent, N.; Kolbel, P.; Schaal, U.; Haep, L.; Regensburger, D.; Wittmann, T.; Klein-Hitpass, L.; Rau, Tilman; Dietel, B.; Meniel, V. S.; Clarke, A. R.; Merkel, S.; Croner, R. S.; Hohenberger, W.; Sturzl, M. (2016). Matricellular protein SPARCL1 regulates tumor microenvironment-dependent endothelial cell heterogeneity in colorectal carcinoma. Journal of clinical investigation, 126(11), pp. 4187-4204. American Society for Clinical Investigation 10.1172/JCI78260
Different tumor microenvironments (TMEs) induce stromal cell plasticity that affects tumorigenesis. The impact of TME-dependent heterogeneity of tumor endothelial cells (TECs) on tumorigenesis is unclear. Here, we isolated pure TECs from human colore
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::570fc1fc55a3e90597342cc3e0426cfc
Autor:
Elisabeth Naschberger, Stephan Kersting, Michael Stürzl, Daniela Regensburger, Noo Li Jeon, Victoria Langer, Thomas Wohlfahrt, Benjamin Schmid, Claudia Handtrack, Andreas Ramming, Philipp Tripal, Jochen Mattner, Maximilian J. Waldner, Nathalie Britzen-Laurent, Somin Lee, Thomas Winkler
Publikováno v:
Inflammatory Bowel Diseases. 24:S24-S24