Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Daniela R. Maccio"'
Autor:
Sean M. Post, Arnold J. Levine, Guillermina Lozano, Tomoo Iwakuma, James G. Jackson, Alfonso Quintás-Cardama, Daniela R. Maccio, David G. Johnson, Gareth L. Bond, Vinod Pant, Amir N. Hamir
MDM2, a negative regulator of p53, is elevated in many cancers that retain wild-type p53. A single nucleotide polymorphism (SNP) in the human MDM2 promoter increases the affinity of Sp1 resulting in elevated MDM2 levels. We generated mice carrying ei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f7681e5325fa6b0e9964cae696b9cba
https://ora.ox.ac.uk/objects/uuid:702563e0-d959-4e08-b728-bd9bde47aeb9
https://ora.ox.ac.uk/objects/uuid:702563e0-d959-4e08-b728-bd9bde47aeb9
Autor:
M. James You, James G. Jackson, Tiffany M. Sills, Hussein A. Abbas, Karen K. Hirschi, Süleyman Coşkun, Guillermina Lozano, Amy L. Hazen, Daniela R. Maccio
Publikováno v:
Cell Stem Cell. 7(5):606-617
Mdm2 is an E3 ubiquitin ligase that targets p53 for degradation. p53(515C) (encoding p53R172P) is a hypomorphic allele of p53 that rescues the embryonic lethality of Mdm2(-/-) mice. Mdm2(-/-) p53(515C/515C) mice, however, die by postnatal day 13 resu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de7c725d867949fa4022c0f68d31d62
Autor:
Yanina Ditamo, Alicia L Degano, Daniela R Maccio, Maria Cristina Pistoresi‐Palencia, German A Roth
Publikováno v:
Immunology & Cell Biology. 83:75-82
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::422a125d1379ba1373f2a28dbbf3cf3a
https://doi.org/10.1111/j.1440-1711.2005.01294.x
https://doi.org/10.1111/j.1440-1711.2005.01294.x
Autor:
Young-Ah Suh, Daniela R. Maccio, Adel K. El-Naggar, Ana C. Elizondo-Fraire, Sean M. Post, Tamara Terzian, Guillermina Lozano, Carolyn S. Van Pelt, James G. Jackson
Publikováno v:
Cancer research. 71(23)
p53 levels are tightly regulated in normal cells, and thus, the wild-type p53 protein is nearly undetectable until stimulated through a variety of stresses. In response to stress, p53 is released from its negative regulators, mainly murine double min
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34c1a40fe6268fa3c71e084aa1d3ff6a
https://pubmed.ncbi.nlm.nih.gov/21983037
https://pubmed.ncbi.nlm.nih.gov/21983037
Autor:
María Virginia López, Guillermo Mazzolini, Diego L. Viale, Eduardo G. Cafferata, Cecilia Carbone, Osvaldo L. Podhajcer, Daniela R. Maccio
Publikováno v:
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
Universidad Nacional de La Plata
instacron:UNLP
Purpose: A33 antigen is a membrane-bound protein expressed in intestinal epithelium that is overexpressed in 95% of primary and metastatic colorectal carcinomas but is absent in most epithelial tissues and tumor types. We hypothesized that A33 promot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ca9237e7cd79c8ea80fa95c931218fd
http://sedici.unlp.edu.ar/handle/10915/82783
http://sedici.unlp.edu.ar/handle/10915/82783
Autor:
Alicia L. Degano, Yanina Ditamo, German A. Roth, María C. Pistoresi-Palencia, Daniela R Maccio
Publikováno v:
Immunology and cell biology. 83(1)
Summary A prominent feature of multiple sclerosis is its high incidence of onset in the third decade of life and its relatively rare onset in persons older than 50 years. In order to study age-related restriction of clinical expression, a comparative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c4d8836b10f989222282a2e75cee24d
https://pubmed.ncbi.nlm.nih.gov/15661044
https://pubmed.ncbi.nlm.nih.gov/15661044
637. Specific Oncolytic Adenovirus Driven by Human A33 Promoter Region for Colorectal Cancer Therapy
Autor:
Diego L. Viale, Daniela R. Maccio, Eduardo G. Cafferata, Osvaldo L. Podhajcer, María Virginia López
Publikováno v:
Molecular Therapy. 13:S245
A33 antigen is a membrane-bound protein that is expressed only in intestinal ephitelium and is over-expressed in most colon cancers. A33 is found in 95% of primary and metastatic colon cancer cells and in 38% of diffuse gastric cancers with uniform a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c63ae73bcc19ccc1ebc72695cdcf9840
https://doi.org/10.1016/j.ymthe.2006.08.713
https://doi.org/10.1016/j.ymthe.2006.08.713
Autor:
Macció, Daniela R.1, Ditamo, Yanina1, Degano, Alicia L.1, Roth, German A.1 garoth@dqb.fcq.tinc.edu.ar
Publikováno v:
Autoimmunity. Feb2004, Vol. 37 Issue 1, p17-25. 9p.
Autor:
Laura Fozzatti
Publikováno v:
Journal of Endocrinology; Mar2007, Vol. 192 Issue 3, p627-637, 11p
Autor:
Monte Stevens
p53: Structure, Functions and Role in Disease discusses the role of p53 dysregulation in different hematologic neoplasms defined by the current WHO classification. The prevalence of p53 aberration, mechanisms of p53 inactivation, regulation of p53 si