Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Daniela Paulsen"'
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144383 (2015)
AIC649 has been shown to directly address the antigen presenting cell arm of the host immune defense leading to a regulated cytokine release and activation of T cell responses. In the present study we analyzed the antiviral efficacy of AIC649 as well
Externí odkaz:
https://doaj.org/article/b82262e2d85347d59e081b156e502a0d
Autor:
Daniela Paulsen, Andreas Urban, Andreas Knorr, Claudia Hirth-Dietrich, Angela Siegling, Hans-Dieter Volk, Andrew A Mercer, Andreas Limmer, Beatrix Schumak, Percy Knolle, Helga Ruebsamen-Schaeff, Olaf Weber
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74605 (2013)
Inactivated orf virus (iORFV), strain D1701, is a potent immune modulator in various animal species. We recently demonstrated that iORFV induces strong antiviral activity in animal models of acute and chronic viral infections. In addition, we found D
Externí odkaz:
https://doaj.org/article/fa712be5788d496f8fefc89646390000
Autor:
Alexandra Bigge, Daniela Paulsen, Christiane Vank, Thomas Berg, Silke Kummer, Ibironke Addy, Holger Zimmermann, Johanna M Eberhard, Dirk Kropeit, Marcus Altfeld, Alen Jambrecina, Manickam Rangaraju, Katja Nedoschinsky, Florian van Bömmel, Hans-Peter Stobernack, Julian Schulze zur Wiesch, Urte Matschl, Adam J. Gehring
Publikováno v:
Journal of Hepatology. 70:e478-e479
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9a30209a77168e86448eb5a38ef8a07
https://doi.org/10.1016/s0618-8278(19)30944-2
https://doi.org/10.1016/s0618-8278(19)30944-2
Autor:
Helga Rübsamen-Schaeff, Andreas Weishaupt, Daniela Paulsen, Niklas Beyersdorf, Sandra Werner, Nelli Wolf, Gabriele Köllner, Thomas Kerkau, Thomas Hünig
Publikováno v:
Journal of Neuroimmunology. 282:63-72
Targeting regulatory T cells (Treg cells) with interleukin-2 (IL-2) constitutes a novel therapeutic approach for autoimmunity. As anti-cancer therapy with IL-2 has revealed substantial toxicities a mutated human IL-2 molecule, termed AIC284 (formerly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::707789e066ff905a3450b4352d35bf4b
https://doi.org/10.1016/j.jneuroim.2015.03.020
https://doi.org/10.1016/j.jneuroim.2015.03.020
Autor:
Holger Zimmermann, Thomas Goldner, Daniela Paulsen, Tobias Wunberg, Judith Baumeister, Peter Lischka, Guy Hewlett, Helga Ruebsamen-Schaeff
Publikováno v:
Antimicrobial Agents and Chemotherapy. 54:1290-1297
Human cytomegalovirus (HCMV) remains a serious threat for immunocompromised individuals, including transplant recipients and newborns. To date, all drugs licensed for the treatment of HCMV infection and disease target the viral DNA polymerase. Althou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0152783584c1c80055bade5015fcd36
https://doi.org/10.1128/aac.01596-09
https://doi.org/10.1128/aac.01596-09
Autor:
Soumi Sukla, Thomas Goldner, Holger Zimmermann, Alexander Birkmann, Hugh J. Field, Daniela Paulsen, Helga Ruebsamen-Schaeff, André Welbers, Dirk Kropeit, Subhajit Biswas
Publikováno v:
Antimicrobial agents and chemotherapy. 58(7)
Herpes simplex virus (HSV) infections can cause considerable morbidity. Transmission of HSV-2 has become a major health concern, since it has been shown to promote transmission of other sexually transmitted diseases. Pritelivir (AIC316, BAY 57-1293)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d667cfb27636682b647939806e619c2b
https://pubmed.ncbi.nlm.nih.gov/24752278
https://pubmed.ncbi.nlm.nih.gov/24752278
Nonnucleoside reverse transcriptase inhibitors (NNRTIs) are important and frequently used elements of highly active antiretroviral therapy (HAART) for the treatment of human immunodeficiency virus type 1 (HIV-1) infection. However, the development of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c1a8bfbac5f5f8988ae19953ca30442
https://europepmc.org/articles/PMC3811302/
https://europepmc.org/articles/PMC3811302/
Autor:
Ulrike Karow, Roland Gugel, Martin Krönke, Gabriele Warnecke, Nikola Baschuk, Olaf Utermöhlen, Wolfgang Deppert, Daniela Paulsen, Frank Brombacher
Publikováno v:
Cancer immunology, immunotherapy : CII. 56(10)
In this report we analyzed the impact of interleukin-4 (IL-4) on tumor-associated simian virus 40 (SV40) large T-antigen (TAg)-specific CD8+ cytotoxic T cells during rejection of syngeneic SV40 transformed mKSA tumor cells in BALB/c mice. Strikingly,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ab826b9e673d270a93be901e235785
https://pubmed.ncbi.nlm.nih.gov/17431618
https://pubmed.ncbi.nlm.nih.gov/17431618
Autor:
Olaf Weber, Andrew A. Mercer, Beatrix Schumak, Angela Siegling, Daniela Paulsen, Percy A. Knolle, Andreas Urban, Andreas Limmer, Helga Ruebsamen-Schaeff, Claudia Hirth-Dietrich, Andreas Knorr, Hans-Dieter Volk
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 9, p e74605 (2013)
PLoS ONE, Vol 8, Iss 9, p e74605 (2013)
Inactivated orf virus (iORFV), strain D1701, is a potent immune modulator in various animal species. We recently demonstrated that iORFV induces strong antiviral activity in animal models of acute and chronic viral infections. In addition, we found D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7eb840bde2e5f4d01282930804118643
https://doi.org/10.1371/journal.pone.0074605
https://doi.org/10.1371/journal.pone.0074605
Autor:
Helga Ruebsamen-Schaeff, Thomas Goldner, Daniela Paulsen, Holger Zimmermann, Tobias Wunberg, Judith Baumeister, Peter Lischka, Guy Hewlett
Publikováno v:
Antiviral Research. 86:A23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::602b4f5d7c80c9b0d8990d26cc4fec1e
https://doi.org/10.1016/j.antiviral.2010.02.343
https://doi.org/10.1016/j.antiviral.2010.02.343