Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Daniela Panakova"'
Autor:
Angela Schulz, Nicola Victoria Müller, Nina Anne van de Lest, Andreas Eisenreich, Martina Schmidbauer, Andrei Barysenka, Bettina Purfürst, Anje Sporbert, Theodor Lorenzen, Alexander M Meyer, Laura Herlan, Anika Witten, Frank Rühle, Weibin Zhou, Emile de Heer, Marion Scharpfenecker, Daniela Panáková, Monika Stoll, Reinhold Kreutz
Publikováno v:
eLife, Vol 8 (2019)
Unraveling the genetic susceptibility of complex diseases such as chronic kidney disease remains challenging. Here, we used inbred rat models of kidney damage associated with elevated blood pressure for the comprehensive analysis of a major albuminur
Externí odkaz:
https://doaj.org/article/3ce65e8761e146108e0f630955c54002
Autor:
Eva Mangelsen, Michael Rothe, Angela Schulz, Aikaterini Kourpa, Daniela Panáková, Reinhold Kreutz, Juliane Bolbrinker
Publikováno v:
Cells, Vol 9, Iss 5, p 1256 (2020)
Glomerular hyperfiltration is an important mechanism in the development of albuminuria. During hyperfiltration, podocytes are exposed to increased fluid flow shear stress (FFSS) in Bowman’s space. Elevated Prostaglandin E2 (PGE2) synthesis and upre
Externí odkaz:
https://doaj.org/article/01b9f5e33ecf4317a8e1a179e7d7035d
Publikováno v:
eLife, Vol 6 (2017)
Organogenesis depends on orchestrated interactions between individual cells and morphogenetically relevant cues at the tissue level. This is true for the heart, whose function critically relies on well-ordered communication between neighboring cells,
Externí odkaz:
https://doaj.org/article/ec2eeadb35874f6eb70e616faf2b8393
Autor:
Angela Schulz, Eva Mangelsen, Aikaterina Kourpa, Debora Kaiser, Michael Rothe, Daniela Panakova, Juliane Bolbrinker, Reinhold Kreutz
Publikováno v:
Journal of Hypertension. 40:e47-e48
Autor:
Aikaterini Kourpa, Eva Mangelsen, Juliane Bolbrinker, Angela Martina Schulz, Michael Rothe, Reinhold Kreutz, Daniela Panakova
Publikováno v:
Journal of Hypertension. 40:e48
Akademický článek
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Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2022)
Molecular and genetic differences between individual cells within tissues underlie cellular heterogeneities defining organ physiology and function in homeostasis as well as in disease states. Transcriptional control of endogenous gene expression has
Externí odkaz:
https://doaj.org/article/96c1f2ddc3ee48aea3d9ff950720cfb0
Autor:
Alison C. McGarvey, Wolfgang Kopp, Dubravka Vučićević, Kenny Mattonet, Rieke Kempfer, Antje Hirsekorn, Ilija Bilić, Marine Gil, Alexandra Trinks, Anne Margarete Merks, Daniela Panáková, Ana Pombo, Altuna Akalin, Jan Philipp Junker, Didier Y.R. Stainier, David Garfield, Uwe Ohler, Scott Allen Lacadie
Publikováno v:
Cell Genomics, Vol 2, Iss 1, Pp 100083- (2022)
Summary: DNA accessibility of cis-regulatory elements (CREs) dictates transcriptional activity and drives cell differentiation during development. While many genes regulating embryonic development have been identified, the underlying CRE dynamics con
Externí odkaz:
https://doaj.org/article/cf31a8127fc441499e23ac3ae15ea61e
Autor:
Anne Margarete Merks, Marie Swinarski, Alexander Matthias Meyer, Nicola Victoria Müller, Ismail Özcan, Stefan Donat, Alexa Burger, Stephen Gilbert, Christian Mosimann, Salim Abdelilah-Seyfried, Daniela Panáková
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
The molecular mechanisms underlying cardiac chamber formation are not well understood. Here, the authors show that planar cell polarity signalling through Wnt5b and Wnt11 coordinates localised and tissue-scale polarised actomyosin contractility in th
Externí odkaz:
https://doaj.org/article/3e6df84b48be483bbf76b4b5ec7606cd
Autor:
Anastasia Felker, Karin D. Prummel, Anne M. Merks, Michaela Mickoleit, Eline C. Brombacher, Jan Huisken, Daniela Panáková, Christian Mosimann
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Late-differentiating second heart field progenitors contribute to atrium, ventricle, and outflow tract in the zebrafish heart but how remains unclear. Here, the authors image heart formation in transgenics based on the cardiopharyngeal gene tbx1 and
Externí odkaz:
https://doaj.org/article/e71f9bcf345740a2b3c7a33df90e5e7d