Výsledky vyhledávání - "Daniela Morales Espinosa"

Akademický článek

Assays for predicting and monitoring responses to lung cancer immunotherapy

Autor: Cristina Teixidó, Niki Karachaliou, Maria González-Cao, Daniela Morales-Espinosa, Rafael Rosell

Publikováno v: Cancer Biology & Medicine, Vol 12, Iss 2, Pp 87-95 (2015)

Immunotherapy has become a key strategy for cancer treatment, and two immune checkpoints, namely, programmed cell death 1 (PD-1) and its ligand (PD-L1), have recently emerged as important targets. The interaction blockade of PD-1 and PD-L1 demonstrat

Externí odkaz: https://doaj.org/article/01ba020a5a854aeba1ba1c940c7f7465

Zobrazit plný text záznamu

Akademický článek

Understanding the function and dysfunction of the immune system in lung cancer: the role of immune checkpoints

Autor: Niki Karachaliou, Maria Gonzalez Cao, Cristina Teixidó, Santiago Viteri, Daniela Morales-Espinosa, Mariacarmela Santarpia, Rafael Rosell

Publikováno v: Cancer Biology & Medicine, Vol 12, Iss 2, Pp 79-86 (2015)

Survival rates for metastatic lung cancer, including non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC), are poor with 5-year survivals of less than 5%. The immune system has an intricate and complex relationship with tumorigenesis;

Externí odkaz: https://doaj.org/article/016e2c745982448c9cd03ab0e0a7f9af

Zobrazit plný text záznamu

Akademický článek

Response of negative estrogen-receptor hepatocarcinoma to tamoxifen, and survival of non-resectable patients

Autor: Jorge García-Leiva, Armando Gamboa-Domínguez, Tania Ceron-Lizarraga, Daniela Morales-Espinosa, Judith Meza-Junco, Oscar Arrieta

Publikováno v: Annals of Hepatology, Vol 5, Iss 4, Pp 263-267 (2006)

Hepatocellular carcinoma is the fifth most common malignant neoplasm worldwide. Most patients are not candidates to surgical treatment. The prognosis of this neoplasm is poor, with an overall survival rate of 8 weeks in unresectable tumors. Estrogen

Externí odkaz: https://doaj.org/article/63d7e553bc18455f9afd2bdbf5f954a8

Zobrazit plný text záznamu

A phase 1/2a open label, multicenter study to assess the safety, tolerability, pharmacokinetics, and efficacy of AFM24 in patients with advanced solid cancers: Study design and rationale

Autor: Omar Saavedra Santa Gadea, Elena Garralda, Juanita Suzanne Lopez, Mark M. Awad, Jacob Stephen Thomas, Crescens Diane Tiu, Daniela Morales-Espinosa, Christa Raab, Bettina Rehbein, Gabriele Hintzen, Kerstin Pietzko, Paulien Ravenstijn, Michael Emig, Anthony B. El-Khoueiry

Publikováno v: Journal of Clinical Oncology. 40:TPS2672-TPS2672

TPS2672 Background: AFM24 is a first-in-class, tetravalent, bispecific, fragment crystallizable-silenced antibody that targets epidermal growth factor receptor-expressing (EGFR+) solid tumors. Of its 4 binding sites, 2 are specific for EGFR, and 2 ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4560271e9ef9f652ce9d4e18733c9232
https://doi.org/10.1200/jco.2022.40.16_suppl.tps2672

Zobrazit plný text záznamu

AFM24 in combination with atezolizumab in patients with advanced EGFR-expressing solid tumors: Phase 1/2a study design and rationale

Autor: Omar Saavedra Santa Gadea, Eric Christenson, Anthony B. El-Khoueiry, Andres Cervantes, Christa Raab, Ulrike Gaertner, Kerstin Pietzko, Gabriele Hintzen, Paulien Ravenstijn, Daniela Morales-Espinosa, Juanita Suzanne Lopez

Publikováno v: Journal of Clinical Oncology. 40:TPS2673-TPS2673

TPS2673 Background: Innate Cell Engagers (ICE) are bispecific molecules that bind both a tumor cell-surface antigen and to CD16A expressed on natural killer (NK) cells and macrophages, inducing antibody-dependent cellular cytotoxicity (ADCC) and anti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::aad1023db99aae48d0e2fef3969b350a
https://doi.org/10.1200/jco.2022.40.16_suppl.tps2673

Zobrazit plný text záznamu

Akademický článek

Erratum to Assays for predicting and monitoring responses to lung cancer immunotherapy

Autor: Cristina Teixidó, Niki Karachaliou, Maria González-Cao, Daniela Morales-Espinosa, Rafael Rosell

Publikováno v: Cancer Biology & Medicine, Vol 12, Iss 3, Pp 259-259 (2015)

Externí odkaz: https://doaj.org/article/f097361686ba45a2bf8c9c1b1f4e0336

Zobrazit plný text záznamu

Development of a gene panel for next-generation sequencing of clinically relevant mutations in cell-free DNA from cancer patients

Autor: Danilo Rocco, Niki Karachaliou, Clara Mayo de-las-Casas, Alejandro Martinez-Bueno, Roberta Sgariglia, Pasquale Pisapia, Umberto Malapelle, Claudio Bellevicine, Francesco Pepe, Rafael Rosell, Caterina De Luca, Miguel Angel Molina-Vila, Daniela Morales-Espinosa, Giancarlo Troncone, Mónica Garzón, Maria Giovanna Russo, Maria Gonzalez-Cao, Santiago Viteri Ramirez, Núria Jordana-Ariza

Publikováno v: British Journal of Cancer

Background: When tumour tissue is unavailable, cell-free DNA (cfDNA)can serve as a surrogate for genetic analyses. Because mutated alleles in cfDNA are usually below 1%, next-generation sequencing (NGS)must be narrowed to target only clinically relev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80b9e8a0e80b5bff04396c855417cbb0
https://doi.org/10.1038/bjc.2017.8

Zobrazit plný text záznamu

Akademický článek

Worldwide mortality from cirrhosis** Worldwide mortality from cirrhosis: An update to 2002 Bosetti C, Levi F Lucchini F, Zatonski WA, Negri E, LaVecchia C J Hepatol 2007;46:827-839. Reprinted with permission.

Autor: Nahum Méndez-Sánchez, Antonio R. Villa, Daniel Zamora-Valdés, Daniela Morales-Espinosa, Misael Uribe

Publikováno v: Annals of Hepatology, Vol 6, Iss 3, Pp 194-195 (2007)

Background/Aims: Cirrhosis mortality has registered large changes over the last few decades. Aim: To report worldwide mortality due to cirrhosis over the period 1980-2002.Methods: Age-standardized (world standard) cirrhosis mortality rates per 100,00

Externí odkaz: https://doaj.org/article/3310b640ef984ec1968d205e66c68e9b

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání