Zobrazeno 1 - 10
of 203
pro vyhledávání: '"Daniela Montesarchio"'
Autor:
Romualdo Troisi, Claudia Riccardi, Kévan Pérez de Carvasal, Michael Smietana, François Morvan, Pompea Del Vecchio, Daniela Montesarchio, Filomena Sica
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 30, Iss , Pp 585-594 (2022)
Despite their unquestionable properties, oligonucleotide aptamers display some drawbacks that continue to hinder their applications. Several strategies have been undertaken to overcome these weaknesses, using thrombin binding aptamers as proof-of-con
Externí odkaz:
https://doaj.org/article/c189695b734244dea0cf4655a5106d10
Publikováno v:
Molecules, Vol 28, Iss 21, p 7278 (2023)
This Special issue is dedicated to the memory of Enrique Pedroso, Professor Emeritus of Organic Chemistry at University of Barcelona, who passed away at the age of 72 in September 2020 [...]
Externí odkaz:
https://doaj.org/article/09f045c9101d4956a8ff5e03e57e0471
Publikováno v:
Molecules, Vol 28, Iss 15, p 5775 (2023)
Ru-based chemotherapy is emerging as an effective alternative to the well-established Pt-based one, typically associated with high toxicity. In this context, our recent efforts were devoted to the preparation of nucleolipid-based Ru(III) complexes ab
Externí odkaz:
https://doaj.org/article/8205f699b01c4250befdb78eb3540f3a
Autor:
Carlotta Peruzzi, Silvia Battistoni, Daniela Montesarchio, Matteo Cocuzza, Simone Luigi Marasso, Alessio Verna, Laura Pasquardini, Roberto Verucchi, Lucrezia Aversa, Victor Erokhin, Pasquale D’Angelo, Salvatore Iannotta
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract In several biomedical applications, the detection of biomarkers demands high sensitivity, selectivity and easy-to-use devices. Organic electrochemical transistors (OECTs) represent a promising class of devices combining a minimal invasivenes
Externí odkaz:
https://doaj.org/article/d95decbdcc994a2a81f2205040d57be1
Autor:
Chiara Platella, Andrea Criscuolo, Claudia Riccardi, Rosa Gaglione, Angela Arciello, Domenica Musumeci, Marina DellaGreca, Daniela Montesarchio
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 7765 (2023)
In-depth studies on the interaction of natural compounds with cancer-related G-quadruplex structures have been undertaken only recently, despite their high potential as anticancer agents, especially due to their well-known and various bioactivities.
Externí odkaz:
https://doaj.org/article/4257a3da53c844359929cfacd7faa77d
Autor:
Maria Grazia Ferraro, Marco Bocchetti, Claudia Riccardi, Marco Trifuoggi, Luigi Paduano, Daniela Montesarchio, Gabriella Misso, Rita Santamaria, Marialuisa Piccolo, Carlo Irace
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6473 (2023)
Based on compelling preclinical evidence concerning the progress of our novel ruthenium-based metallotherapeutics, we are focusing research efforts on challenging indications for the treatment of invasive neoplasms such as the triple-negative breast
Externí odkaz:
https://doaj.org/article/1105430457e54ce2b6fd562608f559f8
Autor:
Claudia Riccardi, Antonella Campanella, Daniela Montesarchio, Pompea Del Vecchio, Rosario Oliva, Luigi Paduano
Publikováno v:
Molecules, Vol 28, Iss 6, p 2800 (2023)
Ruthenium(III) complexes are very promising candidates as metal-based anticancer drugs, and several studies have supported the likely role of human serum proteins in the transport and selective delivery of Ru(III)-based compounds to tumor cells. Here
Externí odkaz:
https://doaj.org/article/00379d93a2f84f709fc2413abe2cd682
Autor:
Chiara Platella, Francesca Ghirga, Domenica Musumeci, Deborah Quaglio, Pasquale Zizza, Sara Iachettini, Carmen D’Angelo, Annamaria Biroccio, Bruno Botta, Mattia Mori, Daniela Montesarchio
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 4070 (2023)
Aiming to identify highly effective and selective G-quadruplex ligands as anticancer candidates, five natural compounds were investigated here, i.e., the alkaloids Canadine, D-Glaucine and Dicentrine, as well as the flavonoids Deguelin and Millettone
Externí odkaz:
https://doaj.org/article/f256c704cf9a4f91838f48adb6fb81fd
Autor:
Andrea Criscuolo, Ettore Napolitano, Claudia Riccardi, Domenica Musumeci, Chiara Platella, Daniela Montesarchio
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2361 (2022)
G-quadruplexes turned out to be important targets for the development of novel targeted anticancer/antiviral therapies. More than 3000 G-quadruplex small-molecule ligands have been described, with most of them exerting anticancer/antiviral activity b
Externí odkaz:
https://doaj.org/article/5523c6c8e44649f48aa9e1583f96a56f
Autor:
Claudia Riccardi, Federica D’Aria, Dominga Fasano, Filomena Anna Digilio, Maria Rosaria Carillo, Jussara Amato, Laura De Rosa, Simona Paladino, Mariarosa Anna Beatrice Melone, Daniela Montesarchio, Concetta Giancola
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12412 (2022)
Two analogues of the MS3 aptamer, which was previously shown to have an exquisite capability to selectively bind and modulate the activity of mutant huntingtin (mHTT), have been here designed and evaluated in their physicochemical and biological prop
Externí odkaz:
https://doaj.org/article/9ee2118330bc416e9eb9c2c184cb036c