Výsledky vyhledávání - "Daniela Miarelli Carvalho"

Dissertation/ Thesis

Estudo farmacocinético e análise da distribuição transplacentária da fluoxetina e seu metabólito em gestantes saudáveis

Publikováno v: Biblioteca Digital de Teses e Dissertações da USPUniversidade de São PauloUSP.

A fluoxetina, um fármaco quiral disponível para uso clínico, como uma mistura racêmica de (S)-(+)-fluoxetina e (R)-(-)-fluoxetina, é a droga mais utilizada no tratamento de estados depressivos durante a gravidez. N-desmetilação de fluoxetina p

Externí odkaz: http://www.teses.usp.br/teses/disponiveis/17/17145/tde-06012017-133152/

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Estudo farmacocinético e análise da distribuição transplacentária da fluoxetina e seu metabólito em gestantes portadoras de diabetes mellitus gestacional

Autor: Daniela Miarelli Carvalho

Publikováno v: Biblioteca Digital de Teses e Dissertações da USP
Universidade de São Paulo (USP)
instacron:USP

A prevalência global de diabetes mellitus gestacional (DMG) é de 16% aproximadamente. O diagnóstico ocorre entre 24 e 28 semanas de gestação, causada por algum grau de intolerância à glicose, a maioria destes casos se resolve após o parto. Ge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82f6d0c23c748287c206e18005d9f2b8
https://doi.org/10.11606/t.17.2020.tde-01062020-091532

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Effect of type 2 diabetes mellitus on the pharmacokinetics and transplacental transfer of nifedipine in hypertensive pregnant women

Autor: Gabriela Campos de Oliveira Filgueira, Vera Lucia Lanchote, Elaine Christine Dantas Moisés, Maria Paula Marques, Osmany Alberto Silva Filgueira, Geraldo Duarte, Ricardo de Carvalho Cavalli, Daniela Miarelli Carvalho

Publikováno v: British Journal of Clinical Pharmacology. 83:1571-1579

Aims Diabetes mellitus can inhibit cytochrome P450 3A4, an enzyme responsible for the metabolism of nifedipine, used for the treatment of hypertension in pregnant women. We aimed to assess the effect of type 2 diabetes mellitus (T2DM) on the pharmaco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::92217d9f4f1dbe4e81cb6cb415ae012e
https://doi.org/10.1111/bcp.13226

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Pharmacokinetics and Transplacental Transfer of Fluoxetine Enantiomers and Their Metabolites in Pregnant Women

Autor: Geraldo Duarte, Glauco Henrique Balthazar Nardotto, Ricardo de Carvalho Cavalli, Daniela Miarelli Carvalho, Vera Lucia Lanchote, Gabriela Campos de Oliveira Filgueira, Elaine Christine Dantas Moisés

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Considering that fluoxetine (FLX) is used to treat depressive states during pregnancy and that it is a cytochrome P450 (CYP)2D6 inhibitor, which is involved in the metabolism of both of its enantiomers, this study aims to describe the enantioselectiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5228d5838c234f974d27399b0384db68
https://pubmed.ncbi.nlm.nih.gov/30346625

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Simultaneous quantification of fluoxetine and norfluoxetine in colostrum and mature human milk using a 2-dimensional liquid chromatography–tandem mass spectrometry system

Autor: Elaine Christine Dantas Moisés, Neila M. Cassiano, Bianca Rebelo Lopes, Quezia B. Cass, Daniela Miarelli Carvalho

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

A two-dimensional liquid chromatography system coupled to triple quadrupole tandem mass spectrometer (2D LC–MS/MS) was employed for the determination of fluoxetine (FLU) and norfluoxetine (N-FLU) in colostrum and mature milk by direct sample inject

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6438cb578872f7038ae4c568635245d6

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Pharmacokinetic study and analysis of transplacental distribution of fluoxetine and its metabolite in healthy pregnant women

Autor: Daniela Miarelli Carvalho

Publikováno v: Biblioteca Digital de Teses e Dissertações da USP
Universidade de São Paulo (USP)
instacron:USP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6486d519c1dd9b426a53ef57742a3bb3

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Effect of type 2 diabetes mellitus on the pharmacokinetics and transplacental transfer of nifedipine in hypertensive pregnant women

Autor: Gabriela Campos de Oliveira, Filgueira, Osmany Alberto Silva, Filgueira, Daniela Miarelli, Carvalho, Maria Paula, Marques, Elaine Christine Dantas, Moisés, Geraldo, Duarte, Vera Lucia, Lanchote, Ricardo Carvalho, Cavalli

Publikováno v: British journal of clinical pharmacology. 83(7)

Diabetes mellitus can inhibit cytochrome P450 3A4, an enzyme responsible for the metabolism of nifedipine, used for the treatment of hypertension in pregnant women. We aimed to assess the effect of type 2 diabetes mellitus (T2DM) on the pharmacokinet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::723ab447b02f092f051e213386c0f2d9
https://pubmed.ncbi.nlm.nih.gov/28042936

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Transplacental Distribution of Lidocaine and Its Metabolite in Peridural Anesthesia Administered to Patients With Gestational Diabetes Mellitus

Autor: Geraldo Duarte, Vera Lucia Lanchote, Maria Paula Marques, Ricardo de Carvalho Cavalli, Daniela Miarelli Carvalho, Gabriela Campos de Oliveira Filgueira, Elaine Christine Dantas Moisés, Luciana de Barros Duarte

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Neonatal effects of drugs administered to mothers before delivery depend on the quantity that crosses the placental barrier, which is determined by the pharmacokinetics of the drug in the mother, fetus, and placenta. Diabetes mellitus can alter the k

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eb1ff2f43f5e5246c79fbe833be41cc
https://europepmc.org/articles/PMC4565472/

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74 Relationship between plasma concentration of nifedipine and pressure control in hypertensive pregnant women

Autor: Geraldo Duarte, Osmany Alberto Silva Filgueira, Maria Paula Marques, Gabriela Campos de Oliveira Filgueira, Elaine Christine Dantas Moisés, Ricardo de Carvalho Cavalli, Vera Lucia Lanchote, Daniela Miarelli Carvalho

Publikováno v: Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health. 6:213-214

Introduction Nifedipine is a calcium channel blocker used in treatment of hypertension in pregnant women. Objective The objective of the present study was to investigate the relation between the plasma concentration of nifedipine and pressure control

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bd681234eb547e7e029a58aa497874f3
https://doi.org/10.1016/j.preghy.2016.08.156

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Analysis of nifedipine in human plasma and amniotic fluid by liquid chromatography-tandem mass spectrometry and its application to clinical pharmacokinetics in hypertensive pregnant women

Autor: Elaine Christine Dantas Moisés, Osmany Alberto Silva Filgueira, Geraldo Duarte, Daniela Miarelli Carvalho, Maria Paula Marques, Ricardo de Carvalho Cavalli, Gabriela Campos de Oliveira Filgueira, Vera Lucia Lanchote

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Nifedipine is a dihydropyridine calcium channel blocker used for the treatment of hypertension in pregnant women. A liquid chromatography-tandem mass spectrometry (LC-MS/MS) method was developed and validated for analysis of nifedipine in human plasm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b6b8ba0ba481029d0b3137fc75b12e3

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