Výsledky vyhledávání - "Daniela Maria Samengo"

Quantitative analysis of autophagic flux by confocal pH-imaging of autophagic intermediates

Autor: Marco De Spirito, Giuseppe Maulucci, Giovambattista Pani, M. Chiarpotto, Massimiliano Papi, Daniela Maria Samengo

Publikováno v: Autophagy

Although numerous techniques have been developed to monitor autophagy and to probe its cellular functions, these methods cannot evaluate in sufficient detail the autophagy process, and suffer limitations from complex experimental setups and/or system

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94390fdaa318619192c9f55b9fd5782c
https://doi.org/10.1080/15548627.2015.1084455

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Low reliability of anti-KIR4.1

Autor: Mariapaola, Marino, Giovanni, Frisullo, Gabriele, Di Sante, Daniela Maria, Samengo, Carlo, Provenzano, Massimiliano, Mirabella, Giovambattista, Pani, Francesco, Ria, Emanuela, Bartoccioni

Publikováno v: Multiple sclerosis (Houndmills, Basingstoke, England). 24(7)

Multiple sclerosis (MS) is an autoimmune disease for which auto-antibodies fully validated as diagnostic and prognostic biomarkers are widely desired. Recently, an immunoreactivity against the inward rectifying potassium channel 4.1 (KIR4.1) has been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4bb2ee52c86b397cdada1c224ccbd6f6
https://pubmed.ncbi.nlm.nih.gov/28548026

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Low reliability of anti-KIR4.183-120 peptide auto-antibodies in multiple sclerosis patients

Autor: Giovambattista Pani, Giovanni Frisullo, Carlo Provenzano, Gabriele Di Sante, Massimiliano Mirabella, Mariapaola Marino, Daniela Maria Samengo, Francesco Ria, Emanuela Bartoccioni

Background: Multiple sclerosis (MS) is an autoimmune disease for which auto-antibodies fully validated as diagnostic and prognostic biomarkers are widely desired. Recently, an immunoreactivity against the inward rectifying potassium channel 4.1 (KIR4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbb46bc7b3660521febcb4fed972ef9a
http://hdl.handle.net/11391/1502449

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Post-natal Deletion of Neuronal cAMP Responsive-Element Binding (CREB)-1 Promotes Pro-inflammatory Changes in the Mouse Hippocampus

Autor: Maria Concetta Geloso, Giovambattista Pani, Fabrizio Michetti, Daniela Maria Samengo, Valentina Di Maria, Elisa Marchese

By taking advantage of a "floxed" conditional CREB mutant mouse (CREB1loxP/loxP), in which postnatal deletion of the Creb gene in the forebrain is driven by the calcium/calmodulin-dependent protein kinase II-α gene (Camk2a) promoter (BCKO mice), we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::513a5a6f531802dce6cc9b243c2de99b
http://hdl.handle.net/10807/100485

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Phase separation of the plasma membrane in human red blood cells as a potential tool for diagnosis and progression monitoring of type 1 diabetes mellitus

Autor: Marco De Spirito, Dario Pitocco, Gabriele Ciasca, Paolo Soda, Giulio Iannello, Giovambattista Pani, Massimiliano Papi, Giuseppe Maulucci, Alessandro Rizzi, Daniela Maria Samengo, Francesca De Leva, Giovanni Ghirlanda, Ermanno Cordelli

Publikováno v: PLoS ONE, Vol 12, Iss 9, p e0184109 (2017)
PLoS ONE

Glycosylation, oxidation and other post-translational modifications of membrane and transmembrane proteins can alter lipid density, packing and interactions, and are considered an important factor that affects fluidity variation in membranes. Red blo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec2a40c0a948c76164a25ec2c7710186
http://hdl.handle.net/10807/122397

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Promotion of Survival and Engraftment of Transplanted Adipose Tissue-Derived Stromal and Vascular Cells by Overexpression of Manganese Superoxide Dismutase

Autor: Silvia Baldari, Daniela Maria Samengo, Angelo Trivisonno, Giovambattista Pani, Gabriele Toietta, Giuliana Di Rocco

Publikováno v: International Journal of Molecular Sciences; Volume 17; Issue 7; Pages: 1082
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 17, Iss 7, p 1082 (2016)

Short-term persistence of transplanted cells during early post-implant period limits clinical efficacy of cell therapy. Poor cell survival is mainly due to the harsh hypoxic microenvironment transplanted cells face at the site of implantation and to

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The redox protein p66(shc) mediates cochlear vascular dysfunction and transient noise-induced hearing loss

Autor: Fabiola Paciello, Rolando Rolesi, Sara Letizia Maria Eramo, Anna Rita Fetoni, Diana Troiani, Giovambattista Pani, Gaetano Paludetti, Daniela Maria Samengo

Publikováno v: Scientific Reports

p66shc, a member of the ShcA protein family, is essential for cellular response to oxidative stress, and elicits the formation of mitochondrial Reactive Oxygen Species (ROS), thus promoting vasomotor dysfunction and inflammation. Accordingly, mice la

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f697612c81650bc9a0b87cdd7c98d98e
http://hdl.handle.net/11588/871825

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Flow Cytofluorimetric Analysis of Anti-LRP4 (LDL Receptor-Related Protein 4) Autoantibodies in Italian Patients with Myasthenia Gravis

Autor: Mariapaola Marino, Giovanni Antonini, Mario Sabatelli, Giovambattista Pani, Flavia Scuderi, Amelia Evoli, Maria Teresa Maiuri, Chengyong Shen, Lin Mei, Emanuela Bartoccioni, Daniela Maria Samengo, Giorgia Saltelli

Publikováno v: PLoS ONE
PLoS ONE, Vol 10, Iss 8, p e0135378 (2015)

Background Myasthenia gravis (MG) is an autoimmune disease in which 90% of patients have autoantibodies against the muscle nicotinic acetylcholine receptor (AChR), while autoantibodies to muscle-specific tyrosine kinase (MuSK) have been detected in h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa1b9609a815255e08e3a9c91ee093c8
http://hdl.handle.net/10807/70194

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The multikinase inhibitor Sorafenib enhances glycolysis and synergizes with glycolysis blockade for cancer cell killing

Autor: Laura Castellini, Alessandro Pontoglio, Anna Chiara Piscaglia, Marta Barba, Johannes N. Spelbrink, Roberto Scatena, Giovambattista Pani, Camilla Bernardini, Daniela Maria Samengo, Giuseppe Maulucci, Maria Ausiliatrice Puglisi, Valentina Tesori, Antonio Gasbarrini

Publikováno v: Scientific Reports, 5
Scientific Reports

Contains fulltext : 154217.pdf (Publisher’s version ) (Open Access) Although the only effective drug against primary hepatocarcinoma, the multikinase inhibitor Sorafenib (SFB) usually fails to eradicate liver cancer. Since SFB targets mitochondria,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4db7f7e3fa99d3430994c22bd13eeb7
http://hdl.handle.net/2066/154217

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Quantitative Analysis of Autophagic Flux by Ratiometric pH-Imaging of Autophagic Intermediates

Autor: Maria Carmela Lauriola, Marco De Spirito, Giuseppe Maulucci, Massimiliano Papi, Gabriele Ciasca, Daniela Maria Samengo, Valentina Palmieri, Giovambattista Pani, M. Chiarpotto

Publikováno v: Biophysical Journal. 110:596a

Although numerous techniques have been developed to monitor autophagy to probe its cellular functions, these methods can’t evaluate in sufficient detail the autophagy process, and suffer limitations from complex experimental setups and/or systemati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37560c8607a0fcbf780bc34d91c09548
https://doi.org/10.1016/j.bpj.2015.11.3183

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