Zobrazeno 1 - 10
of 213
pro vyhledávání: '"Daniela Marasco"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Protein-protein interactions (PPIs) play critical roles in a wide range of biological processes including the dysregulation of cellular pathways leading to the loss of cell function, which in turn leads to diseases. The dysfunction of several signali
Externí odkaz:
https://doaj.org/article/9df2d2eeda8a459aa5fb24d97d664573
Autor:
Mario Troisi, Salvatore Del Prete, Salvatore Troisi, Daniela Marasco, Michele Rinaldi, Ciro Costagliola
Publikováno v:
Biomedicines, Vol 12, Iss 9, p 1945 (2024)
The authors performed an ex vivo and in vivo evaluation of the ultrastructural effects on the conjunctival epithelial cells of a new multiple-action tear substitute containing cross-linked hyaluronic acid, lipids and trehalose (Trimix®), using scann
Externí odkaz:
https://doaj.org/article/849c7cbdb67449e7b95329a5eff54a4c
Autor:
Nada H. Eisa, Vincent M. Crowley, Asif Elahi, Vamsi Krishna Kommalapati, Michael A. Serwetnyk, Taoufik Llbiyi, Sumin Lu, Kashish Kainth, Yasmeen Jilani, Daniela Marasco, Abdeljabar El Andaloussi, Sukyeong Lee, Francis T.F. Tsai, Paulo C. Rodriguez, David Munn, Esteban Celis, Hasan Korkaya, Abdessamad Debbab, Brian Blagg, Ahmed Chadli
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108308- (2023)
Summary: Low response rates and immune-related adverse events limit the remarkable impact of cancer immunotherapy. To improve clinical outcomes, preclinical studies have shown that combining immunotherapies with N-terminal Hsp90 inhibitors resulted i
Externí odkaz:
https://doaj.org/article/f4ba062b1eb84919b99e30fb877c3d61
Autor:
Barbara Maciejewska, Flavia Squeglia, Agnieszka Latka, Mario Privitera, Sebastian Olejniczak, Paulina Switala, Alessia Ruggiero, Daniela Marasco, Eliza Kramarska, Zuzanna Drulis-Kawa, Rita Berisio
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Virion-associated depolymerases are large trimeric and multi-domain proteins that constitute the phage arsenal to degrade the polysaccharide layers in their bacterial host. Thus, as recombinant proteins, they are endowed with huge potential
Externí odkaz:
https://doaj.org/article/875fa14b7dbf4eb29c00194a76650a8c
Autor:
Daniele Florio, Daniela Marasco
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 2, p 811 (2024)
Acute myeloid leukemia (AML) is a heterogeneous group of diseases classified into various types on the basis of distinct features concerning the morphology, cytochemistry and cytogenesis of leukemic cells. Among the different subtypes, the group “A
Externí odkaz:
https://doaj.org/article/9775596bfe094fd8b8f42a0316cb6595
Publikováno v:
Reports, Vol 6, Iss 1, p 10 (2023)
65 consecutive patients with presumed microbial keratitis and negative culture tests for bacteria and fungi obtained by corneal curettage were evaluated. All patients had undergone local broad spectrum antibiotic therapy for at least 5 days with no c
Externí odkaz:
https://doaj.org/article/de26cc008145453b842590778b79edae
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2022)
The JAK-STAT pathway is a crucial cellular signaling cascade, including an intricate network of Protein–protein interactions (PPIs) responsible for its regulation. It mediates the activities of several cytokines, interferons, and growth factors and
Externí odkaz:
https://doaj.org/article/83e7390819424863a631379a18805934
Autor:
Daniele Florio, Sara La Manna, Concetta Di Natale, Marilisa Leone, Flavia Anna Mercurio, Fabiana Napolitano, Anna Maria Malfitano, Daniela Marasco
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 14704 (2022)
In a protein, point mutations associated with diseases can alter the native structure and provide loss or alteration of functional levels, and an internal structural network defines the connectivity among domains, as well as aggregate/soluble states
Externí odkaz:
https://doaj.org/article/ad096b0803094513a23389315feb9f96
Autor:
Daniela Benigno, Antonella Virgilio, Ivana Bello, Sara La Manna, Valentina Vellecco, Mariarosaria Bucci, Daniela Marasco, Elisabetta Panza, Veronica Esposito, Aldo Galeone
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 14921 (2022)
In this paper, we study the biological properties of two TBA analogs containing one and two extra G-tetrads, namely TBAG3 and TBAG4, respectively, and two further derivatives in which one of the small loops at the bottom (TBAG41S) or the large loop a
Externí odkaz:
https://doaj.org/article/cded1a861ade4767852a12b87fcfc7fa
Autor:
Raziye Piranlioglu, EunMi Lee, Maria Ouzounova, Roni J. Bollag, Alicia H. Vinyard, Ali S. Arbab, Daniela Marasco, Mustafa Guzel, John K. Cowell, Muthushamy Thangaraju, Ahmed Chadli, Khaled A. Hassan, Max S. Wicha, Esteban Celis, Hasan Korkaya
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Dissemination of tumor cells from the primary site is an early event. Here, the authors show that the early disseminated tumor cells are actively cleared by the host cytotoxic T lymphocytes induced by the primary tumor and that infiltration of granul
Externí odkaz:
https://doaj.org/article/ab8309125be1466c9f20adaacc94d582