Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Daniela M Witten"'
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 10, p e1011509 (2023)
A major goal of computational neuroscience is to build accurate models of the activity of neurons that can be used to interpret their function in circuits. Here, we explore using functional cell types to refine single-cell models by grouping them int
Externí odkaz:
https://doaj.org/article/8823e4ef344645d9893b569a5f5a4796
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0252345 (2021)
Calcium imaging has led to discoveries about neural correlates of behavior in subcortical neurons, including dopamine (DA) neurons. However, spike inference methods have not been tested in most populations of subcortical neurons. To address this gap,
Externí odkaz:
https://doaj.org/article/9cbcfe83b19f424abf6223e9f9530f2c
Autor:
Andrew H Beck, Ziming Weng, Daniela M Witten, Shirley Zhu, Joseph W Foley, Phil Lacroute, Cheryl L Smith, Robert Tibshirani, Matt van de Rijn, Arend Sidow, Robert B West
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8768 (2010)
Gene expression microarrays are the most widely used technique for genome-wide expression profiling. However, microarrays do not perform well on formalin fixed paraffin embedded tissue (FFPET). Consequently, microarrays cannot be effectively utilized
Externí odkaz:
https://doaj.org/article/4b188761151c4748a7d11746f8c8cdb2
Autor:
Yaoxing Huang, Michael Krasnitz, Raul Rabadan, Daniela M Witten, Yang Song, Arnold J Levine, David D Ho, Harlan Robins
Publikováno v:
PLoS ONE, Vol 3, Iss 9, p e3214 (2008)
This manuscript describes a novel strategy to improve HIV DNA vaccine design. Employing a new information theory based bioinformatic algorithm, we identify a set of nucleotide motifs which are common in the coding region of HIV, but are under-represe
Externí odkaz:
https://doaj.org/article/2c794a981a894583a84b3f46eca0de9d
A major goal of computational neuroscience is to build accurate models of the activity of neurons that can be used to interpret their function in circuits. Here, we explore usingfunctional cell typesto refine single-cell models by grouping them into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec993fd3aba2efd631cb099865b824cf
https://doi.org/10.1101/2023.02.28.530327
https://doi.org/10.1101/2023.02.28.530327
Autor:
Fumitaka Inoue, Martin Kircher, Beth Martin, Gregory M. Cooper, Daniela M. Witten, Michael T. McManus, Nadav Ahituv, Jay Shendure
Publikováno v:
Genome research, vol 28, iss 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::128e5780f38bbd709b06e3620eface84
https://escholarship.org/uc/item/1g71x4q7
https://escholarship.org/uc/item/1g71x4q7
Autor:
Daniela M, Witten, Robert, Tibshirani
Publikováno v:
The annals of applied statistics. 2(3)
We consider the problem of testing the significance of features in high-dimensional settings. In particular, we test for differentially-expressed genes in a microarray experiment. We wish to identify genes that are associated with some type of outcom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fa47ed8dfd2bc87c641f5181f0282342
https://pubmed.ncbi.nlm.nih.gov/19756232
https://pubmed.ncbi.nlm.nih.gov/19756232
Publikováno v:
Journal of the American Statistical Association. 104(486):698-699
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8995068d87ef87cd8152a44b25fb5c9d
http://pubs.amstat.org/doi/abs/10.1198/jasa.2009.0143
http://pubs.amstat.org/doi/abs/10.1198/jasa.2009.0143