Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Daniela M Ciobota"'
Autor:
Cassandra L Stowe, Thomas A Burley, Helen Allan, Maria Vinci, Gabriela Kramer-Marek, Daniela M Ciobota, Gary N Parkinson, Tara L Southworth, Giulia Agliardi, Alastair Hotblack, Mark F Lythgoe, Bruce R Branchini, Tammy L Kalber, James C Anderson, Martin A Pule
Publikováno v:
eLife, Vol 8 (2019)
Bioluminescence imaging (BLI) is ubiquitous in scientific research for the sensitive tracking of biological processes in small animal models. However, due to the attenuation of visible light by tissue, and the limited set of near-infrared bioluminesc
Externí odkaz:
https://doaj.org/article/28633a3c3ec14220bcd7ff7a3ce49ce3
Autor:
Gabriela Kramer-Marek, Graham Smith, Wim J.G. Oyen, Kevin J. Harrington, Louis Allott, Daniela M. Ciobota, Rhodri Smith, Thomas A. Burley, Chiara Da Pieve, Carlos D. Martins
Representative 3D-rendering of segmented MCF-7, MDA-MB-468 and MDA-MB-231 xenografts following PET/CT image acquisition 3 h after 89Zr-DFO-ZHER3:8698 injection.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d18fd39f5aab8a016445ea75c5b6e5a
https://doi.org/10.1158/1078-0432.22464824
https://doi.org/10.1158/1078-0432.22464824
Autor:
Gabriela Kramer-Marek, Graham Smith, Wim J.G. Oyen, Kevin J. Harrington, Louis Allott, Daniela M. Ciobota, Rhodri Smith, Thomas A. Burley, Chiara Da Pieve, Carlos D. Martins
Purpose: Recent studies have highlighted a role of HER3 in HER2-driven cancers (e.g., breast cancer), implicating the upregulation of the receptor in resistance to HER-targeted therapies and Hsp90 inhibitors (e.g., AUY922). Therefore, we have develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::319e1decfc82bee5d18d838c987f213f
https://doi.org/10.1158/1078-0432.c.6525815.v1
https://doi.org/10.1158/1078-0432.c.6525815.v1
Autor:
Gabriela Kramer-Marek, Graham Smith, Wim J.G. Oyen, Kevin J. Harrington, Louis Allott, Daniela M. Ciobota, Rhodri Smith, Thomas A. Burley, Chiara Da Pieve, Carlos D. Martins
Materials and Methods Fig. S1. Time course of AUY922 treatment in BT-474 and MCF-7 cells. Fig. S2. Effects of AUY922 and PPP treatment in low and high HER2-expressing breast cancer cell lines. Fig. S3. Effect of HRG stimulation in AUY922 and PPP trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bbae65be7548e00f5e6357352e0f7a2
https://doi.org/10.1158/1078-0432.22464815.v1
https://doi.org/10.1158/1078-0432.22464815.v1
Autor:
Louis Allott, Thomas A Burley, Gabriela Kramer-Marek, Daniela M. Ciobota, Chiara Da Pieve, Graham Smith, Kevin J. Harrington, Carlos D. Martins, Wim J.G. Oyen
Publikováno v:
Journal of Nuclear Medicine
In head and neck squamous cell cancer, the human epidermal growth factor receptor 1 (EGFR) is the dominant signaling molecule among all members of the family. So far, cetuximab is the only approved anti-EGFR monoclonal antibody used for the treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac636b7224c59e4fa38aff178a3a19ad
https://doi.org/10.2967/jnumed.118.216069
https://doi.org/10.2967/jnumed.118.216069
Autor:
Gabriela Kramer-Marek, Helen Allan, Alastair Hotblack, Tara L. Southworth, James C. Anderson, Giulia Agliardi, Bruce R. Branchini, Thomas A Burley, Cassandra L Stowe, Gary N. Parkinson, Mark F. Lythgoe, Martin Pule, Maria Vinci, Daniela M. Ciobota, Tammy L. Kalber
Publikováno v:
eLife, Vol 8 (2019)
eLife
eLife
Bioluminescence imaging (BLI) is ubiquitous in scientific research for the sensitive tracking of biological processes in small animal models. However, due to the attenuation of visible light by tissue, and the limited set of near-infrared bioluminesc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::478cc4bb3eddf2a6ebc59ce45e1b93fd
https://doi.org/10.7554/elife.45801
https://doi.org/10.7554/elife.45801
Autor:
Tammy L. Kalber, Gabriela Kramer-Marek, Alastair Hotblack, Gary N. Parkinson, Martin Pule, Cassandra L Stowe, Giulia Agliardi, Bruce R. Branchini, Maria Vinci, Daniela M. Ciobota, Helen Allan, Mark F. Lythgoe, Thomas A Burley, Tara L. Southworth, James C. Anderson
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d9fb9773ac5fd5c4d3d862e70f93517
https://doi.org/10.7554/elife.45801.022
https://doi.org/10.7554/elife.45801.022
Autor:
Carlos D, Martins, Chiara, Da Pieve, Thomas A, Burley, Rhodri, Smith, Daniela M, Ciobota, Louis, Allott, Kevin J, Harrington, Wim J G, Oyen, Graham, Smith, Gabriela, Kramer-Marek
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 24(8)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f5cf04643e34fad19909bc4f6585c163
https://pubmed.ncbi.nlm.nih.gov/29437790
https://pubmed.ncbi.nlm.nih.gov/29437790
Autor:
Carlos D. Martins, Graham Smith, Gabriela Kramer-Marek, Andrew Vardon, Louis Allott, Daniela M. Ciobota, Chiara Da Pieve
Publikováno v:
Bioconjugate chemistry. 27(8)
The human epidermal growth factor receptor 3 (HER3) is overexpressed in several cancers, being linked to a more resistant phenotype and hence leading to poor patient prognosis. Imaging HER3 is challenging owing to the modest receptor number (50000 re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18c344f151f95c86005cacca8aa9a9f2
https://pubmed.ncbi.nlm.nih.gov/27357023
https://pubmed.ncbi.nlm.nih.gov/27357023
Autor:
Chris Jones, Geetha Balaragah, Andrew D.J. Pearson, Daniela M. Ciobota, Martin O. Leach, Alice Agliano, Florence l. Raynaud, Paul Workman, Paul A. Clarke, Nada M.S. Al-Saffar
Publikováno v:
Cancer Research. 73:5399-5399
Although radiotherapy is used to treat more than 50% of all cancer patients, in glioblastomas the percentage of success is limited due to the radioresistance of glioma cells. Reports have shown that part of this phenomenon has to be attributed to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a414da22646377447c3922763b6df75e
https://doi.org/10.1158/1538-7445.am2013-5399
https://doi.org/10.1158/1538-7445.am2013-5399