Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Daniela M, Arduino"'
Autor:
Jennifer Wettmarshausen, Valerie Goh, Kai-Ting Huang, Daniela M. Arduino, Utkarsh Tripathi, Anja Leimpek, Yiming Cheng, Alexandros A. Pittis, Toni Gabaldón, Dejana Mokranjac, György Hajnóczky, Fabiana Perocchi
Publikováno v:
Cell Reports, Vol 25, Iss 6, Pp 1425-1435.e7 (2018)
Summary: The mitochondrial calcium uniporter is a highly selective ion channel composed of species- and tissue-specific subunits. However, the functional role of each component still remains unclear. Here, we establish a synthetic biology approach to
Externí odkaz:
https://doaj.org/article/ba54a49daa084585978270d366902706
Autor:
Paulina, Sander, Michael, Feng, Maria K, Schweitzer, Fabiola, Wilting, Sophie M, Gutenthaler, Daniela M, Arduino, Sandra, Fischbach, Lisa, Dreizehnter, Alessandra, Moretti, Thomas, Gudermann, Fabiana, Perocchi, Johann, Schredelseker
Publikováno v:
British journal of pharmacologyREFERENCES. 178(22)
Treatment of cardiac arrhythmia remains challenging due to severe side effects of common anti-arrhythmic drugs. We previously demonstrated that mitochondrial CaHerewe screened 727 compounds with a history of use in human clinical trials in a three-st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::56840889edbce4cd096df6aedce01c96
https://pubmed.ncbi.nlm.nih.gov/34287836
https://pubmed.ncbi.nlm.nih.gov/34287836
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2277
The mitochondrial calcium uniporter (MCU ) is an essential protein of the inner mitochondrial membrane that mediates the uptake of calcium into mitochondria of virtually all mammalian tissues, regulating cell metabolism, signaling, and death. MCU-med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f60869cb5a5536d45531153c309a3cb9
https://pubmed.ncbi.nlm.nih.gov/34080145
https://pubmed.ncbi.nlm.nih.gov/34080145
Autor:
Thomas Gudermann, Johann Schredelseker, Alessandra Moretti, Fabiola Wilting, Sophie M. Gutenthaler, Michael Feng, Fabiana Perocchi, Maria K. Schweitzer, Lisa Dreizehnter, Paulina Sander, Sandra Fischbach, Daniela M. Arduino
Publikováno v:
Br. J. Pharmacol., DOI: 10.1111/bph.15630 (2021)
BACKGROUND AND PURPOSE Treatment of cardiac arrhythmia remains challenging due to severe side effects of common anti-arrhythmic drugs. We previously demonstrated that mitochondrial Ca2+ uptake in cardiomyocytes represents a promising new candidate st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bca45140881f4bae1f319f83d68fa682
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=62649
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=62649
Autor:
Fabiana Perocchi, Daniela M. Arduino
Publikováno v:
The Journal of Physiology. 596:2717-2733
Mitochondria are pivotal organelles in calcium (Ca2+ ) handling and signalling, constituting intracellular checkpoints for numerous processes that are vital for cell life. Alterations in mitochondrial Ca2+ homeostasis have been linked to a variety of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::364b14c4290de37b0ff7e3c13f65b022
https://doi.org/10.1113/jp274959
https://doi.org/10.1113/jp274959
Autor:
Diogo Martins Branco, Daniela M Arduino, A. Raquel Esteves, Diana F F Silva, Sandra M Cardoso, Catarina Oliveira
Publikováno v:
Frontiers in Aging Neuroscience, Vol 2 (2010)
Parkinson’s disease (PD) is the most common progressive neurodegenerative movement disorder, characterized by the selective loss of nigrostriatal dopaminergic neurons, and the presence of intracellular insoluble proteinaceous inclusions, known as L
Externí odkaz:
https://doaj.org/article/de1db54aec4b43e19f8a746ea49872f3
Autor:
Anja Leimpek, Valerie Goh, Daniela M. Arduino, Alexandros A. Pittis, Jennifer Wettmarshausen, Fabiana Perocchi, Toni Gabaldón, Dejana Mokranjac, György Hajnóczky, Kai-Ting Huang, Yiming Cheng, Utkarsh Tripathi
Publikováno v:
Recercat. Dipósit de la Recerca de Catalunya
instname
Cell Reports, Vol 25, Iss 6, Pp 1425-1435.e7 (2018)
Cell Rep. 25, 1425-1435 (2018)
Cell Reports
instname
Cell Reports, Vol 25, Iss 6, Pp 1425-1435.e7 (2018)
Cell Rep. 25, 1425-1435 (2018)
Cell Reports
The mitochondrial calcium uniporter is a highly selective ion channel composed of species- and tissue-specific subunits. However, the functional role of each component still remains unclear. Here, we establish a synthetic biology approach to dissect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db2483261d51f3ecc911bee26796d18
https://pubmed.ncbi.nlm.nih.gov/30403999
https://pubmed.ncbi.nlm.nih.gov/30403999
Autor:
Daniela M, Arduino, Fabiana, Perocchi
Publikováno v:
The Journal of physiology. 596(14)
Mitochondria are pivotal organelles in calcium (Ca(2+)) handling and signalling, constituting intracellular checkpoints for numerous processes that are vital for cell life. Alterations in mitochondrial Ca(2+) homeostasis have been linked to a variety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2f6cc24979045fec82f7ab3b970c01db
https://pubmed.ncbi.nlm.nih.gov/29319185
https://pubmed.ncbi.nlm.nih.gov/29319185
Autor:
Sarah R. Nathan, Fabiana Perocchi, Justin J. Wilson, Daniela M. Arduino, Samantha N. MacMillan, Nicholas W. Pino
Publikováno v:
Inorganic chemistry. 56(6)
The mixed-valent oxo-bridged ruthenium complex [(HCO2)(NH3)4Ru(μ-O)Ru(NH3)4(O2CH)]3+, known as Ru360, is a selective inhibitor of mitochondrial calcium uptake. Although this compound is useful for studying the role of mitochondrial calcium in biolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5541e3448d12fec4d8ce8cd69d6b8f5a
https://pubmed.ncbi.nlm.nih.gov/28244741
https://pubmed.ncbi.nlm.nih.gov/28244741
Publikováno v:
Methods in Molecular Biology ISBN: 9781493922871
Parkinson's disease (PD) is a multifactorial and clinically complex age-related movement disorder. The cause of its most common form (sporadic PD, sPD) is unknown, but one prominent causal factor is mitochondrial dysfunction. Although several genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9affc73be27263bb3fbaa25ef848b8a
https://doi.org/10.1007/978-1-4939-2288-8_31
https://doi.org/10.1007/978-1-4939-2288-8_31