Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Daniela Lenggenhager"'
Autor:
Anne-Laure Leblond, Birgit Helmchen, Maliki Ankavay, Daniela Lenggenhager, Jasna Jetzer, Fritjof Helmchen, Hueseyin Yurtsever, Rossella Parrotta, Marc E. Healy, Amiskwia Pöschel, Enni Markkanen, Nasser Semmo, Martin Ferrié, Laurence Cocquerel, Harald Seeger, Helmut Hopfer, Beat Müllhaupt, Jérôme Gouttenoire, Darius Moradpour, Ariana Gaspert, Achim Weber
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Hepatitis E virus (HEV) infection, one of the most common forms of hepatitis worldwide, is often associated with extrahepatic, particularly renal, manifestations. However, the underlying mechanisms are incompletely understood. Here, we repor
Externí odkaz:
https://doaj.org/article/2e0acd6efb7748d6ab4fa79b0d50a92c
Autor:
Rebekka Wegmann, Lorenz Bankel, Yasmin Festl, Kate Lau, Sohyon Lee, Fabian Arnold, Valentina Cappelletti, Aaron Fehr, Paola Picotti, Konstantin J. Dedes, Daniel Franzen, Daniela Lenggenhager, Peter K. Bode, Martin Zoche, Holger Moch, Christian Britschgi, Berend Snijder
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Personalized treatment for patients with advanced solid tumors critically depends on the deep characterization of tumor cells from patient biopsies. Here, we comprehensively characterize a pan-cancer cohort of 150 malignant serous effusion (
Externí odkaz:
https://doaj.org/article/6040e8b387b24847845fb184ce64f893
Autor:
Giulia Tochtermann, Miriam Nowack, Cristina Hagen, Niels J. Rupp, Kristian Ikenberg, Martina A. Broglie, Francesca Saro, Daniela Lenggenhager, Peter K. Bode
Publikováno v:
Cancer Medicine, Vol 12, Iss 11, Pp 12198-12207 (2023)
Abstract Background Fine‐needle aspiration cytology (FNAC) represents an important diagnostic tool for the workup of salivary gland (SG) lesions. The Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) is a six‐tiered system for stan
Externí odkaz:
https://doaj.org/article/1a932862ff284d14ae937c5522ae6639
Autor:
Christian K. Hirt, Tijmen H. Booij, Linda Grob, Patrik Simmler, Nora C. Toussaint, David Keller, Doreen Taube, Vanessa Ludwig, Alexander Goryachkin, Chantal Pauli, Daniela Lenggenhager, Daniel J. Stekhoven, Christian U. Stirnimann, Katharina Endhardt, Femke Ringnalda, Lukas Villiger, Alexander Siebenhüner, Sofia Karkampouna, Marta De Menna, Janette Beshay, Hagen Klett, Marianna Kruithof-de Julio, Julia Schüler, Gerald Schwank
Publikováno v:
Cell Genomics, Vol 2, Iss 2, Pp 100095- (2022)
Summary: Pancreatic cancer (PDAC) is a highly aggressive malignancy for which the identification of novel therapies is urgently needed. Here, we establish a human PDAC organoid biobank from 31 genetically distinct lines, covering a representative ran
Externí odkaz:
https://doaj.org/article/528029a5e0b440e9b617944420259540
Autor:
Joana Vieira Barbosa, Beat Müllhaupt, Felix Brunner, Magdalena Filipowicz Sinnreich, David Semela, Matteo Montani, Gieri Cathomas, Jörg Neuweiler, Jérôme Gouttenoire, Florent Artru, Alexandre Louvet, Philippe Mathurin, Christine Sempoux, Daniela Lenggenhager, Achim Weber, Darius Moradpour, Montserrat Fraga
Publikováno v:
Swiss Medical Weekly, Vol 151, Iss 1718 (2021)
BACKGROUND AND AIM Acute decompensation and death have been observed in patients with acute hepatitis E virus (HEV) infection and preexisting liver cirrhosis. However, the clinical, laboratory and histological features need to be fully characterised
Externí odkaz:
https://doaj.org/article/a99da2ad018c47b3a72e08b7f581c345
Autor:
Daniela Lenggenhager, Manoj Amrutkar, Petra Sántha, Monica Aasrum, Johannes-Matthias Löhr, Ivar P. Gladhaug, Caroline S. Verbeke
Publikováno v:
Cells, Vol 8, Iss 1, p 23 (2019)
Activated pancreatic stellate cells (PSCs) play a central role in the tumor stroma of pancreatic ductal adenocarcinoma (PDAC). Given the limited availability of patient-derived PSCs from PDAC, immortalized PSC cell lines of murine and human origin ha
Externí odkaz:
https://doaj.org/article/77432b1f851149b38e86f50682b82d4f
Autor:
Nadine Stanek, Peter Bauerfeind, Guido Herzog, Henriette Heinrich, Matthias Sauter, Daniela Lenggenhager, Cäcilia Reiner, Markus G. Manz, Jeroen S. Goede, Benjamin Misselwitz
Publikováno v:
Case Reports in Hematology, Vol 2016 (2016)
Protein losing enteropathy (PLE) refers to excessive intestinal protein loss, resulting in hypoalbuminemia. Underlying pathologies include conditions leading to either reduced intestinal barrier or lymphatic congestion. We describe the case of a pati
Externí odkaz:
https://doaj.org/article/fbe7775248c8403586ffabd3b11e0349
Publikováno v:
Acta Cytologica.
Introduction: In most cases the diagnostic workup of pleural mesotheliomas (MPM) starts with cytological examination of pleural effusion, but histology is needed to confirm the diagnosis. The introduction of BAP1 and MTAP immunohistochemistry have be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::afe82d928b85681f367a12e89e666af3
https://doi.org/10.1159/000530002
https://doi.org/10.1159/000530002
Autor:
Pedro David Wendel Garcia, Bernhard Morell, Gregor Brüllmann, Philipp K. Buehler, Christoph Gubler, Cäcilia S. Reiner, Daniela Lenggenhager, Christoph Jüngst, Martina Haberecker, Simon Bütikofer, Ewerton Marques Maggio, Beat Müllhaupt
Publikováno v:
Liver International
BACKGROUND & AIMS: Little is known about cholestasis, including its most severe variant secondary sclerosing cholangitis (SSC), in critically ill patients with coronavirus disease 19 (COVID-19). In this study, we analysed the occurrence of cholestati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51afe9e4a32eb5630a8debf46c0166f4
https://doi.org/10.1111/liv.14971
https://doi.org/10.1111/liv.14971
Autor:
Andreas E. Moor, Nina Frey, Ying K. Tam, Denis V Victorov, Costanza Borrelli, Kevin Holden, Melissa K Dennis, Martin Jinek, Dominik Witzigmann, Rurika Oka, Susanne Kreutzer, Lukas Villiger, Gerald Schwank, Martina Hruzova, Lucas Kissling, Norbert Pardi, Daniela Lenggenhager, Markus Stoffel, Ruben van Boxtel, Zacharias Kontarakis, Beat Thöny, Sean C. Semple, Anastasia P. Kadina, John A. Walker, Johannes Häberle, Sabina Egli, Tanja Rothgangl, Noëlle Bakker, Martin Pacesa, Weihong Qi, Paulo J.C. Lin, Drew Weissman
Publikováno v:
Nature Biotechnology, 39 (8)
Nature Biotechnology
Nature biotechnology, 39(August 2021). Nature Publishing Group
Nature Biotechnology
Nature biotechnology, 39(August 2021). Nature Publishing Group
Most known pathogenic point mutations in humans are C center dot G to T center dot A substitutions, which can be directly repaired by adenine base editors (ABEs). In this study, we investigated the efficacy and safety of ABEs in the livers of mice an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ae069a0668f90ce5cdbb49415cc632
https://doi.org/10.1038/s41587-021-00933-4
https://doi.org/10.1038/s41587-021-00933-4