Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Daniela Klewe-Nebenius"'
Autor:
Yang Lin, Koustav Roy, Shuji Ioka, Rintaro Otani, Mao Amezawa, Yukiko Ishikawa, Yoan Cherasse, Mahesh K. Kaushik, Daniela Klewe-Nebenius, Li Zhou, Masashi Yanagisawa, Yo Oishi, Tsuyoshi Saitoh, Michael Lazarus
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Insomnia is associated with psychiatric illnesses such as bipolar disorder or schizophrenia. Treating insomnia improves psychotic symptoms severity, quality of life, and functional outcomes. Patients with psychiatric disorders are often d
Externí odkaz:
https://doaj.org/article/54ec9a2e91c5458794cfece383912e6b
Autor:
Yibing Wang, Liqin Cao, Chia-Ying Lee, Tomohiko Matsuo, Kejia Wu, Greg Asher, Lijun Tang, Tsuyoshi Saitoh, Jamie Russell, Daniela Klewe-Nebenius, Li Wang, Shingo Soya, Emi Hasegawa, Yoan Chérasse, Jiamin Zhou, Yuwenbin Li, Tao Wang, Xiaowei Zhan, Chika Miyoshi, Yoko Irukayama, Jie Cao, Julian P. Meeks, Laurent Gautron, Zhiqiang Wang, Katsuyasu Sakurai, Hiromasa Funato, Takeshi Sakurai, Masashi Yanagisawa, Hiroshi Nagase, Reiko Kobayakawa, Ko Kobayakawa, Bruce Beutler, Qinghua Liu
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
TMT is a chemical that evokes innate defensive behaviors yet the molecular mechanisms are not well understood. Here the authors perform a large-scale forward genetics screen in mice and identify Trpa1, a pungency/irritancy receptor, as a chemosensor
Externí odkaz:
https://doaj.org/article/8f55e531aa4244bb85f1b7f3abfc81f3
Autor:
Junmin Peng, Makito Sato, Chi-Yu Lee, Xiaojie Yang, Miyo Kakizaki, Tingting Lou, Noriko Hotta-Hirashima, Qinghua Liu, Yonghao Yu, Zhiqiang Wang, Masashi Yanagisawa, Satoru Takahashi, Aya Ikkyu, Hiromasa Funato, Shuang Zhou, Tomoyuki Fujiyama, Yuxin Li, Satomi Kanno, Yukino Ogawa, Liqin Cao, Chengyuan Ma, Jing Ma, Chika Miyoshi, Xue Gao, Daniela Klewe-Nebenius
Publikováno v:
Nature. 558:435-439
Sleep and wake have global effects on brain physiology, from molecular changes1–4 and neuronal activities to synaptic plasticity3–7. Sleep–wake homeostasis is maintained by the generation of a sleep need that accumulates during waking and dissi
Autor:
Masashi Yanagisawa, Katsuyasu Sakurai, Chika Miyoshi, Jamie Russell, Chia-Ying Lee, Yuwenbin Li, Hiromasa Funato, Greg Asher, Emi Hasegawa, Lijun Tang, Li Wang, Julian P. Meeks, Jie Cao, Tao Wang, Xiaowei Zhan, Kejia Wu, Qinghua Liu, Zhiqiang Wang, Tsuyoshi Saitoh, Reiko Kobayakawa, Takeshi Sakurai, Liqin Cao, Yoan Cherasse, Jiamin Zhou, Yibing Wang, Shingo Soya, Tomohiko Matsuo, Ko Kobayakawa, Yoko Irukayama, Hiroshi Nagase, Daniela Klewe-Nebenius, Laurent Gautron, Bruce Beutler
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Innate behaviors are genetically encoded, but their underlying molecular mechanisms remain largely unknown. Predator odor 2,4,5-trimethyl-3-thiazoline (TMT) and its potent analog 2-methyl-2-thiazoline (2MT) are believed to activate specific odorant r
Autor:
Adrian Zumsteg, Gerhard Christofori, Daniela Klewe-Nebenius, Karin Strittmatter, Helena Antoniadis
Publikováno v:
Carcinogenesis; Vol 31
The Rip1Tag2 transgenic mouse model of pancreatic beta-cell carcinogenesis has been instrumental in identifying several hallmarks of cancer, including tumor cell evasion from apoptosis, tumor angiogenesis and tumor invasion. Moreover, Rip1Tag2 mice h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad10b77468a591edbcb04e8b8271227d
http://doc.rero.ch/record/298993/files/bgq109.pdf
http://doc.rero.ch/record/298993/files/bgq109.pdf
Autor:
Hitoshi Niwa, Branko Zevnik, Austin Smith, Ian Chambers, Daniela Klewe-Nebenius, Jennifer Nichols, Hans R. Schöler, Konstantinos Anastassiadis
Publikováno v:
ResearcherID
Oct4 is a mammalian POU transcription factor expressed by early embryo cells and germ cells. We report that the activity of Oct4 is essential for the identity of the pluripotential founder cell population in the mammalian embryo. Oct4-deficient embry