Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Daniela Keinhörster"'
Autor:
Anke Siegmund, Muhammad Awais Afzal, Felix Tetzlaff, Daniela Keinhörster, Fabio Gratani, Kerstin Paprotka, Martin Westermann, Sandor Nietzsche, Christiane Wolz, Martin Fraunholz, Christian A. Hübner, Bettina Löffler, Lorena Tuchscherr
Publikováno v:
Virulence, Vol 12, Iss 1, Pp 1186-1198 (2021)
A large proportion of clinical S. aureus isolates that carry an inactive Agr system are associated with persistent infection that is difficult to treat. Once S. aureus is inside the bloodstream, it can cross the endothelial barrier and invade almost
Externí odkaz:
https://doaj.org/article/d2be581b9a5d43d987b9dcb1ebf0c0ca
Autor:
Petra Horvatek, Andrea Salzer, Andrew Magdy Fekry Hanna, Fabio Lino Gratani, Daniela Keinhörster, Natalya Korn, Marina Borisova, Christoph Mayer, Dominik Rejman, Ulrike Mäder, Christiane Wolz
Publikováno v:
PLoS Genetics, Vol 16, Iss 12, p e1009282 (2020)
The stringent response is characterized by the synthesis of the messenger molecules pppGpp, ppGpp or pGpp (here collectively designated (pp)pGpp). The phenotypic consequences resulting from (pp)pGpp accumulation vary among species and can be mediated
Externí odkaz:
https://doaj.org/article/64b54852d2cc4a109726ec504c086cee
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
The stringent response is characterized by the synthesis of the alarmone (p)ppGpp. The phenotypic consequences resulting from (p)ppGpp accumulation vary among species, and for several pathogenic bacteria, it has been shown that the activation of the
Externí odkaz:
https://doaj.org/article/47a1d1b1b886459e9bdc9302185ba4bd
Autor:
Franziska Leipoldt, Javier Santos-Aberturas, Dennis P. Stegmann, Felix Wolf, Andreas Kulik, Rodney Lacret, Désirée Popadić, Daniela Keinhörster, Norbert Kirchner, Paulina Bekiesch, Harald Gross, Andrew W. Truman, Leonard Kaysser
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Metalloproteinase inhibitors are leads for drug development, but their biosynthetic pathways are often unknown. Here the authors show that the acyl branched warhead of actinonin and matlystatins derives from an ethylmalonyl-CoA-like pathway and the s
Externí odkaz:
https://doaj.org/article/33d55bdb2e15447e910a355a7a9c3566
Autor:
Anke, Siegmund, Muhammad Awais, Afzal, Felix, Tetzlaff, Daniela, Keinhörster, Fabio, Gratani, Kerstin, Paprotka, Martin, Westermann, Sandor, Nietzsche, Christiane, Wolz, Martin, Fraunholz, Christian A, Hübner, Bettina, Löffler, Lorena, Tuchscherr
Publikováno v:
Virulence
article-version (VoR) Version of Record
article-version (VoR) Version of Record
A large proportion of clinical S. aureus isolates that carry an inactive Agr system are associated with persistent infection that is difficult to treat. Once S. aureus is inside the bloodstream, it can cross the endothelial barrier and invade almost
Autor:
Andrew W. Truman, Paulina Bekiesch, Leonard Kaysser, Rodney Lacret, Daniela Keinhörster, Franziska Leipoldt, Désirée Popadić, Andreas Kulik, Harald Gross, Felix Wolf, Javier Santos-Aberturas, Dennis P. Stegmann, Norbert Kirchner
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Nature Communications
Nature Communications
Metalloproteinase inhibitors often feature hydroxamate moieties to facilitate the chelation of metal ions in the catalytic center of target enzymes. Actinonin and matlystatins are potent metalloproteinase inhibitors that comprise rare N-hydroxy-2-pen
Autor:
Christopher Weidenmaier, Jean C. Lee, Andrea Salzer, Alejandra Duque-Jaramillo, Daniela Keinhörster, Shilpa Elizabeth George, Gabriella Marincola, Christiane Wolz
InStaphylococcus aureus, the capsular polysaccharide (CP) protects against phagocytosis, but also hinders adherence to endothelial cells and matrix proteins. Its biosynthesis is tightly controlled resulting in a heterogeneous phenotype within a popul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e5c0f40c02768bad56cbc8c08a4096e
https://doi.org/10.1101/614925
https://doi.org/10.1101/614925
Publikováno v:
International journal of medical microbiology : IJMM. 309(6)
Staphylococcus aureus produces different secondary cell wall glycopolymers such as wall teichoic acids (WTA) and capsular polysaccharides (CP). These structures play an important role in S. aureus colonization, pathogenesis and bacterial evasion of t
Autor:
Stefanie, Wanner, Jessica, Schade, Daniela, Keinhörster, Nicola, Weller, Shilpa E, George, Larissa, Kull, Jochen, Bauer, Timo, Grau, Volker, Winstel, Henriette, Stoy, Dorothee, Kretschmer, Julia, Kolata, Christiane, Wolz, Barbara M, Bröker, Christopher, Weidenmaier
Publikováno v:
Nature microbiology. 2
Autor:
Volker Winstel, Barbara M. Bröker, Nicola Weller, Daniela Keinhörster, Larissa Kull, Jochen Bauer, Shilpa Elizabeth George, Christopher Weidenmaier, Dorothee Kretschmer, Jessica Schade, Stefanie Wanner, Julia Kolata, Henriette Stoy, Timo Grau, Christiane Wolz
Publikováno v:
Nature Microbiology. 2
Nature Microbiology 2, 16257 (2017); published online 23 January 2017; corrected 13 March 2017 In the version of this Article originally published, the horizontal bars in Fig. 1a that indicate statistical differences were incorrectly placed. This has