Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Daniela Karlsson"'
Autor:
Adyary Fallarero, Gulsah Bayraktar, Pia Vuorela, Carola Schiller, Ezgi Turunc, Manuel Krug, Sülünay Parlar, Guliz Armagan, Ayfer Yalcin, Vildan Alptüzün, Christoph A. Sotriffer, Kristina Leuner, Daniela Karlsson, Malgorzata Burek, Michaela Prinz, Ulrike Holzgrabe, Ercin Erciyas, Carola Förster
Publikováno v:
European Journal of Pharmaceutical Sciences. 49:603-613
Given the fundamentally multifactorial character of Alzheimer's disease (AD), addressing more than one target for disease modification or therapy is expected to be highly advantageous. Here, following the cholinergic hypothesis, we aimed to inhibit b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07a2933633e6fc31f6477b0ff4f6452a
https://doi.org/10.1016/j.ejps.2013.04.024
https://doi.org/10.1016/j.ejps.2013.04.024
Autor:
Claudia Mayer, Gerda Brunhofer, Ohm Prakash, Thomas Erker, Pia Vuorela, C. Gopi Mohan, Daniela Karlsson, Adyary Fallarero
Publikováno v:
European Journal of Pharmaceutical Sciences. 47:190-205
The role of butyrylcholinesterase (BChE) in the progression of Alzheimer’s disease (AD) has recently become more crucial. In the AD brain, selective BChE inhibitors have been demonstrated to have a beneficial effect in vivo , probably by recovering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3209d6accb5b12814bae27cdea33675
https://doi.org/10.1016/j.ejps.2012.05.014
https://doi.org/10.1016/j.ejps.2012.05.014
Publikováno v:
Planta Medica. 78
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c77c71a5d445adf70cd140c68befb84e
https://doi.org/10.1055/s-0032-1320489
https://doi.org/10.1055/s-0032-1320489
Autor:
Gerda Brunhofer, Adyary Fallarero, Daniela Karlsson, Ana Batista-Gonzalez, Pia Vuorela, C. Gopi Mohan, Pravin S. Shinde
Publikováno v:
Bioorganicmedicinal chemistry. 20(22)
The presented project started by screening a library consisting of natural and natural based compounds for their acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) inhibitory activity. Active compounds were chemically clustered into groups
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b8ec31ec8e57be2d4e8bbedaadeb967
https://pubmed.ncbi.nlm.nih.gov/23062825
https://pubmed.ncbi.nlm.nih.gov/23062825
Autor:
Michaela Prinz, Thomas Erker, Gerda Brunhofer, Przemyslaw Guzik, Adyary Fallarero, Daniela Karlsson, Pia Vuorela, Ulrike Holzgrabe
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 45(1-2)
In this contribution, a chemical collection of aromatic compounds was screened for inhibition on butyrylcholinesterase (BChE)’s hydrolase activity using Ellman’s reaction. A set of diarylimidazoles was identified as highly selective inhibitors of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3576a06e4cc18ad27db18b4cdaf3b720
https://pubmed.ncbi.nlm.nih.gov/22108346
https://pubmed.ncbi.nlm.nih.gov/22108346
Autor:
Reko Leino, Pravin S. Shinde, Pia Vuorela, Daniela Karlsson, C. Gopi Mohan, Adyary Fallarero, C P Anju, Igor Busygin
Publikováno v:
Natural Product Communications. 9:1934578X1400900
Butyrylcholinesterase (BChE) inhibitors were identified from a collection containing cinchonine, cinchonidine and synthetic derivatives, and further characterized using cytotoxicity and molecular docking studies. The most active ones were: (10≡)-10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b85fc4878210a92e325a85deb2020051
https://doi.org/10.1177/1934578x1400900404
https://doi.org/10.1177/1934578x1400900404