Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Daniela Jabes"'
Autor:
Nicoletta Basilico, Silvia Parapini, Anna Sparatore, Sergio Romeo, Paola Misiano, Livia Vivas, Vanessa Yardley, Simon L. Croft, Annette Habluetzel, Leonardo Lucantoni, Laurent Renia, Bruce Russell, Rossarin Suwanarusk, Francois Nosten, Giulio Dondio, Chiara Bigogno, Daniela Jabes, Donatella Taramelli
Publikováno v:
Molecules, Vol 22, Iss 12, p 2102 (2017)
Natural products are a prolific source for the identification of new biologically active compounds. In the present work, we studied the in vitro and in vivo antimalarial efficacy and ADME-Tox profile of a molecular hybrid (AM1) between 4-aminoquinoli
Externí odkaz:
https://doaj.org/article/109aa3a57b6d49ebb3938d568b370008
Autor:
Anders Løbner-Olesen, Daniela Jabes, Margherita Sosio, Sonia I. Maffioli, Thomas T. Thomsen, Cristina Brunati, Eleonora Gaspari, Stefano Donadio
Publikováno v:
Brunati, C, Thomsen, T T, Gaspari, E, Maffioli, S, Sosio, M, Jabes, D, Løbner-Olesen, A & Donadio, S 2018, ' Expanding the potential of NAI-107 for treating serious ESKAPE pathogens : synergistic combinations against Gram-negatives and bactericidal activity against non-dividing cells ', The Journal of antimicrobial chemotherapy, vol. 73, no. 2, pp. 414-424 . https://doi.org/10.1093/jac/dkx395
Journal of Antimicrobial Chemotherapy
Journal of Antimicrobial Chemotherapy
Objectives: To characterize NAI-107 and related lantibiotics for their in vitro activity against Gram-negative pathogens, alone or in combination with polymyxin, and against non-dividing cells or biofilms of Staphylococcus aureus. NAI-107 was also ev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::381d47312df9beda1a10259773ddfaaa
https://curis.ku.dk/portal/da/publications/expanding-the-potential-of-nai107-for-treating-serious-eskape-pathogens(724509c8-87da-4032-808f-1667c1560b2b).html
https://curis.ku.dk/portal/da/publications/expanding-the-potential-of-nai107-for-treating-serious-eskape-pathogens(724509c8-87da-4032-808f-1667c1560b2b).html
Autor:
Letizia Brandi, Stefano Donadio, Roberto Spurio, Eleonora Gaspari, Cheng-Guang He, Daniela Jabes, Sonia I. Maffioli, Margherita Sosio, Attilio Fabbretti
Publikováno v:
Antimicrobial Agents and Chemotherapy. 59:4560-4568
A chemical derivative of the thiopeptide GE2270A, designated NAI003, was found to possess a substantially reduced antibacterial spectrum in comparison to the parent compound, being active against just a few Gram-positive bacteria. In particular, NAI0
Autor:
Paola Corona, Sandra Piras, Antonio Carta, Maria Antonietta Pirisi, Daniela Jabes, Irene Briguglio
Publikováno v:
Anti-Infective Agents. 11:75-89
Autor:
Stefano Donadio, Simona Riva, Gianpaolo Candiani, Gabriella Romano, Daniela Jabes, Cristina Brunati
Publikováno v:
Antimicrobial Agents and Chemotherapy. 55:1671-1676
NAI-107 is a novel lantibiotic active against Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus (MRSA), glycopeptide-intermediate S. aureus (GISA), and vancomycin-resistant enterococci (VRE). The aim of this study was to e
Autor:
Paola Guglierame, Irene Briguglio, Daniela Jabes, Sandra Piras, Antonio Carta, Paola Corona, Paola Molicotti, Stefania Anna Lucia Zanetti, Michele Francesco Luigi Palomba
Publikováno v:
European Journal of Medicinal Chemistry. 46:320-326
A number of quinolone derivatives have been reported to possess anti-mycobacterial activity. Generally. Mycobacterium tuberculosis isolates expressing resistance to both isoniazid and rifampin are susceptible to fluoroquinolones. Benzotriazole is a h
Publikováno v:
Applied Microbiology and Biotechnology. 88:1261-1267
Microbial pathogens are becoming increasingly resistant to available treatments, and new antibiotics are badly needed, but the pipeline of compounds under development is scarce. Furthermore, the majority of antibiotics under development are improved
Autor:
Daniela Jabes, Antonio Carta, Stefania Anna Lucia Zanetti, Michele Francesco Luigi Palomba, Paola Molicotti, Sandra Piras
Publikováno v:
Anti-Infective Agents in Medicinal Chemistry. 7:134-147
A number of novel quinolone derivatives have been recentlyreported to posses in vitro and in vivo anti mycobacterial and DNA gyrase inhibition activities. It is known that mycobacteria expressing resistance to both isoniazid and rifampin (multi-drug
Synthesis and Preliminary Biological Characterization of New Semisynthetic Derivatives of Ramoplanin
Autor:
Anna Checchia, Matteo Giannone, Gianbattista Panzone, Augusto Canavesi, Romeo Ciabatti, Franca Castiglione, Gianpaolo Candiani, Sonia I. Maffioli, Elena Michelucci, Paolo Simone Tiseni, Cristina Brunati, Ettore Marzorati, Daniela Jabes, Gabriella Romano
Publikováno v:
Journal of Medicinal Chemistry. 50:3077-3085
Ramoplanin is a glycolipodepsipeptide antibiotic active against Gram-positive bacteria including vancomycin-resistant enterococci. Ramoplanin inhibits bacterial cell wall biosynthesis by a mechanism different from that of glycopeptides and hence does
Autor:
Paolo Cozzi, Paolo Lusso, Mauro S. Malnati, Priscilla Biswas, Daniela Jabes, Francesca Sironi, Adolfo García-Sastre, Silvia Ghezzi, Christina Guzzo, Nicola Mongelli, Carles Martínez-Romero
Publikováno v:
Journal of Translational Medicine
Background Combined antiretroviral therapy has drastically reduced mortality and morbidity of HIV-infected individuals. Nevertheless long-term toxicity and appearance of viral resistance hampers the prolonged effectiveness of combination therapy, req