Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Daniela Hoeller"'
Autor:
Ivan Dikic, Daniela Hoeller
The proteasome is one of the major degradation machineries in eukaryotic cells. It terminates the existence of thousands of short-lived, damaged, misfolded or otherwise obsolete proteins and plays pivotal roles in protein quality control and other vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48a3165eff727b0417bc2871c626c852
https://europepmc.org/articles/PMC5127301/
https://europepmc.org/articles/PMC5127301/
Autor:
Baraa Zuhaili, Magdalena Fossum, Christoph Theopold, Raphael Gheerardyn, Elof Eriksson, Scott Visovatti, Feng Yao, Tobias Hirsch, Henry Svensson, Oliver Bleiziffer, Patrik Velander, Mike K. Chen, Daniela Hoeller
Publikováno v:
Wound Repair and Regeneration. 16:288-293
Diabetic wounds result in significant morbidity, prolonged hospitalization, and enormous health-care expenses. Pigs have been shown to have wound healing resembling that in humans. The aim of this study was to develop a large-animal model for diabeti
Autor:
Elof Eriksson, Patrik Velander, Jan Vranckx, Akira Takedo, Christoph Theopold, Nicola Petrie, Daniela Hoeller, Feng Yao
Publikováno v:
Wound Repair and Regeneration. 15:657-664
The concept of using growth factor therapy to induce wound repair has been endorsed in studies that show reduced growth factors in wound fluid from chronic and aged wounds. In this study, we used cell suspensions of allogenic keratinocytes as gene-de
Autor:
Vladimir V. Rogov, Sebastian Wagner, Daniela Hoeller, Christina-Maria Hecker, Ivan Dikic, Volker Dötsch
Publikováno v:
Molecular Cell. 26(6):891-898
Ubiquitin (Ub)-binding domains (UBDs) are key elements in conveying Ub-based cellular signals. UBD-containing proteins interact with ubiquitinated targets and control numerous biological processes. They themselves undergo UBD-dependent monoubiquitina
Publikováno v:
Molecular Therapy. 13:1133-1141
Employing the tetracycline repressor tetR and the wild-type hCMV major immediate-early promoter, we have developed a highly sensitive tetracycline-inducible transcription switch in mammalian cells (T-REx™; Invitrogen, Carlsbad, CA, USA). In view of
Publikováno v:
Current Opinion in Cell Biology. 17:107-111
Spatial and temporal separation of signal transduction pathways often determines the specificity in cellular responses. Recent advances have improved our understanding of how growth factor signalling is influenced by the formation of molecular comple
Autor:
Daniela Hoeller, Jarek Slama, Elof Eriksson, Scott Visovatti, Nicola Petrie, Jan Vranckx, Hanka Augustinova, Feng Yao
Publikováno v:
Wound Repair and Regeneration. 13:51-60
We have previously reported that endogenous vascular endothelial growth factor (VEGF) concentration in older pig wounds peaked later and at one-fourth the level of young pigs. These data suggested that VEGF might play a major role in the healing of f
Publikováno v:
Plastic and Reconstructive Surgery. :1215-1219
Autor:
Frank B. Furnari, Ivan Dikic, Jiuhong Yu, Oliver Bogler, Daniela Hoeller, Webster K. Cavenee, Mirko H. H. Schmidt
Publikováno v:
Molecular and Cellular Biology. 24:8981-8993
The assembly of the Cbl-SETA/CIN85-endophilin complex at the C terminus of the epidermal growth factor receptor (EGFR) following ligand activation mediates its internalization and ubiquitination. We found that the SETA/CIN85-interacting protein Alix/
Publikováno v:
Journal of Virology. 78:5756-5765
By selectively regulating the expression of the trans -dominant-negative mutant polypeptide UL9-C535C, of herpes simplex virus type 1 (HSV-1) origin binding protein UL9 with the tetracycline repressor ( tetR )-mediated gene switch, we recently genera