Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Daniela Fraccarollo"'
Autor:
Britta Stapel, Daniela Fraccarollo, Mechthild Westhoff-Bleck, Johann Bauersachs, Ralf Lichtinghagen, Kirsten Jahn, Alexandra Burkert, Vanessa Buchholz, Stefan Bleich, Helge Frieling, Xiao-Qi Ding, Kai G. Kahl
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Major depressive disorder (MDD) is frequently associated with poor response to treatment. Common antidepressants target neurotransmission and neuronal plasticity, which require adequate energy supply. As imaging studies indicate disturbances
Externí odkaz:
https://doaj.org/article/819fbfb95e584ec486d50583610f9b77
Autor:
Laura M. Wienecke, Lars H. Lemke, Daniela Fraccarollo, Paolo Galuppo, Fabian Kockelmann, Jens Thol, Johann Bauersachs, Mechthild Westhoff-Bleck
Publikováno v:
International Journal of Cardiology Congenital Heart Disease, Vol 10, Iss , Pp 100418- (2022)
Background: Adults with congenital heart disease (ACHD) display changes in adaptive immunity related to early open-heart surgery and subsequent incidental thymectomy. In acquired heart failure (HF) systemic inflammation, innate and adaptive immune ce
Externí odkaz:
https://doaj.org/article/95487b70addf4fb39669c332aecf53d7
Autor:
Sebastian Bertele, Ivo Heitland, Daniela Fraccarollo, Britta Stapel, Johann Bauersachs, Mechthild Westhoff-Bleck, Kai G. Kahl
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
Background and aimAdverse childhood experiences (ACEs) are a major risk factor for unfavorable behavioral, mental and health outcomes later in life. However, the precise pathway via which ACEs convey these risks, in particular regarding health outcom
Externí odkaz:
https://doaj.org/article/b2144c98019d44fb9b9f92a09049d523
Autor:
Daniela Fraccarollo, Jonas Neuser, Julian Möller, Christian Riehle, Paolo Galuppo, Johann Bauersachs
Publikováno v:
eLife, Vol 10 (2021)
Immature neutrophils and HLA-DRneg/low monocytes expand in cancer, autoimmune diseases and viral infections, but their appearance and immunoregulatory effects on T-cells after acute myocardial infarction (AMI) remain underexplored. We found an expans
Externí odkaz:
https://doaj.org/article/344cf0f62b5c4b56aa68c412d7d366b3
Autor:
Daniel B Hoffmann, Daniela Fraccarollo, Paolo Galuppo, Stefan Frantz, Johann Bauersachs, Jochen Tillmanns
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0248196 (2021)
IntroductionRegulating excessive activation of fibroblasts may be a promising target to optimize extracellular matrix deposition and myocardial stiffness. Fibroblast activation protein alpha (FAP) is upregulated in activated fibroblasts after myocard
Externí odkaz:
https://doaj.org/article/5900e04e1c704dd5876002ad5f63943d
Autor:
Jonas Neuser, Paolo Galuppo, Daniela Fraccarollo, Jens Willig, Tibor Kempf, Dominik Berliner, Johann Bauersachs, Julian Daniel Widder
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183670 (2017)
Transcatheter aortic valve replacement (TAVR) is the method of choice for patients with severe aortic valve stenosis, who are ineligible or at high risk for surgery. Though TAVR leads to a significant reduction in mortality, a notable amount of patie
Externí odkaz:
https://doaj.org/article/f77b0102da5f49bf8c7635657c4e6f59
Autor:
Ulrike Flierl, Daniela Fraccarollo, Julian D Widder, Jan Micka, Jonas Neuser, Johann Bauersachs, Andreas Schäfer
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123621 (2015)
Platelet activation associated with endothelial dysfunction and impaired endogenous platelet inhibition is part of the cardiovascular phenotype of congestive heart failure (CHF) and contributes to the increased risk for thromboembolic complications.
Externí odkaz:
https://doaj.org/article/93e120a0ba614b7d8a24a9f974a38b6d
Autor:
Jochen Tillmanns, Stefan Frantz, Johann Bauersachs, D. B. Hoffmann, Daniela Fraccarollo, Paolo Galuppo
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0248196 (2021)
PLoS ONE
PLoS ONE
Introduction Regulating excessive activation of fibroblasts may be a promising target to optimize extracellular matrix deposition and myocardial stiffness. Fibroblast activation protein alpha (FAP) is upregulated in activated fibroblasts after myocar
Autor:
Johann Bauersachs, Paolo Galuppo, Julian Möller, Christian Riehle, Jonas Neuser, Daniela Fraccarollo
Immature neutrophils and HLA-DRneg/low monocytes expand in cancer, autoimmune diseases and viral infections, but their appearance and functional characteristics after acute myocardial infarction (AMI) remain underexplored. We found an expansion of ci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c4de2ab747cda1699af7e5e1b740f9c
https://doi.org/10.1101/2020.09.21.306118
https://doi.org/10.1101/2020.09.21.306118
Autor:
Paolo Galuppo, Claus-Jürgen Scholz, Svenja Thomas, Daniela Fraccarollo, Johann Bauersachs, Denise Hilfiker-Kleiner
Publikováno v:
Hypertension (Dallas, Tex. : 1979)
Supplemental Digital Content is available in the text.
Myocardial infarction (MI) is a major cause of death worldwide. Here, we identify the macrophage MR (mineralocorticoid receptor) as a crucial pathogenic player in cardiac wound repair after
Myocardial infarction (MI) is a major cause of death worldwide. Here, we identify the macrophage MR (mineralocorticoid receptor) as a crucial pathogenic player in cardiac wound repair after