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of 64
pro vyhledávání: '"Daniela Fattori"'
Autor:
Daniela Fattori
Publikováno v:
TECA, Vol 12, Iss 5ns, Pp 37-54 (2022)
On May 28, 1494 the Venetian Senate ordered the destruction by fire of all copies of a printed pamphlet containing a defamatory 'frotula' against the Dominican Order written by the Neapolitan friar Domenico de Carpanis, who was previously a Dominican
Externí odkaz:
https://doaj.org/article/be29cc957d1344128ba89d85a696dde1
Autor:
Fincham, Christopher I., Bressan, Alessandro, D’Andrea, Piero, Ettorre, Alessandro, Giuliani, Sandro, Mauro, Sandro, Meini, Stefania, Paris, Marielle, Quartara, Laura, Rossi, Cristina, Squarcia, Antonella, Valenti, Claudio, Daniela, Fattori, Maggi, Carlo Alberto
Publikováno v:
In Bioorganic & Medicinal Chemistry 15 March 2012 20(6):2091-2100
Autor:
Marina Porcelloni, Elena Marastoni, Maria Altamura, Rose-Marie Catalioto, Sandro Giuliani, Carlo Alberto Maggi, Sandro Mauro, Stefania Meini, Cristina Rossi, Piero D’Andrea, Alessandro Ettorre, Daniela Fattori
Publikováno v:
Journal of Medicinal Chemistry. 53:4148-4165
As part of a project aimed at the identification of a series of small, orally available antagonists for the hNK(2) receptor, starting from one of our capped dipeptide libraries, we succeeded in the chemical optimization of the first identified leads,
Publikováno v:
Expert Opinion on Therapeutic Patents. 19:919-941
For20 years, pharmaceutical companies and academic centers have been developing bradykinin antagonists. The patent literature on these molecules (up to and including 2004) has been analyzed previously in this journal in two review articles.The aim of
Publikováno v:
Synthesis. 2009:1305-1308
N-Bromosuccinimide-mediated electrophilic aromatic bromination of a series of anilines substituted with an electron-withdrawing group in the meta position was investigated. The regioselectivity of the reaction is markedly dependent on the polarity of
Autor:
Marina Porcelloni, Stefania Meini, Andrea Madami, Sandro Giuliani, Maria Altamura, Cristina Rossi, Alessandro Ettorre, Daniela Fattori, Alessandro Sisto, Piero D’Andrea
Publikováno v:
ChemMedChem. 3:1048-1060
The NK(2) receptor belongs to the family of tachykinin neurotransmitters. It has been reported to be involved in several pathological conditions, and selective antagonists are potentially useful drugs for the treatment of asthma, irritable bowel synd
Publikováno v:
Journal of Medicinal Chemistry. 51:1505-1529
Publikováno v:
Drugs in R & D. 9:217-227
In the last 20 years the advent of new technologies, such as high-throughput screening (HTS) and combinatorial chemistry, has produced new tools for the discovery of biologically active molecules. In the past decade, fragment-based drug discovery has
Autor:
Maria Altamura, Franco Cardinali, Alessandro Sisto, Daniela Fattori, Piero D’Andrea, Cristina Rossi
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 17:4841-4844
MEN 15596 is a small molecule, potent and selective antagonist of NK 2 receptor, possessing high affinity and potency at the guinea-pig and human receptors whose pharmacological characterization has been recently published. Here we report how the cor
Autor:
Sandro Giuliani, Cristina Rossi, Valerio Caciagli, Laura Quartara, Rossano Nannicini, Stefania Meini, Alessandro Bressan, Daniela Fattori, Christopher I. Fincham, Fernando Catrambone, Piero D’Andrea, Elena Marastoni, Carlo Alberto Maggi, Claudio Valenti, Rosa Terracciano, Martina Gensini, Patrizia Felicetti, Marielle Paris
Publikováno v:
Journal of Medicinal Chemistry. 50:550-565
Recently we reported on the design and synthesis of a novel class of selective nonpeptide bradykinin (BK) B2 receptor antagonists (J. Med. Chem. 2006, 3602-3613). This work led to the discovery of MEN 15442, an antagonist with subnanomolar affinity f