Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Daniela Faiardi"'
1
Discovery and optimization of pyrrolo[1,2-a]pyrazinones leads to novel and selective inhibitors of PIM kinases
Autor: Arturo Galvani, Nilla Avanzi, Giovanni Cervi, Barbara Salom, Marisa Montemartini, Daniela Faiardi, Claudia Piutti, Gianpaolo Fogliatto, Daniele Donati, Gianluca Papeo, Christian Orrenius, Danilo Mirizzi, Elena Casale, Aurelio Marsiglio, Francesco Casuscelli, Ferguson Ron, Matteo D'anello, Eduard R. Felder, Elena Ardini
Publikováno v: Bioorganic & Medicinal Chemistry. 21:7364-7380
A novel series of PIM inhibitors was derived from a combined effort in natural product-inspired library generation and screening. The novel pyrrolo[1,2-a]pyrazinones initial hits are inhibitors of PIM isoforms with IC50 values in the low micromolar r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a3ba0082a180982c89ff216890ca016
https://doi.org/10.1016/j.bmc.2013.09.054
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2
ChemInform Abstract: Synthesis of N-Trifluoroacetyl Derivatives of Enantiomeric 2,5,6-Trideoxy-5-amino Hexoses from Non-Carbohydrate Precursors
Autor: Claudio Fuganti, Giovanni Fronza, Giuseppe Pedrocchi-Fantoni, Domenica Pizzi, Daniela Faiardi
Publikováno v: ChemInform. 21
The D-lyxo and D-ribo methyl-N-trifluoroacetyl-2,5,6-trideoxy-5-amino hexofuranosides (13) and (14) are accessible from carbohydrate-like acyclic C7 products 3 and 5, whereas the 3-C-methyl analog of 13 is prepared in similar way from 15. Azide treat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c9b71c30eae7796ea544a9e424150343
https://doi.org/10.1002/chin.199001319
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3
Synthesis ofN-Trifluoroacetyl Derivatives of Enantiomeric 2,5,6-Trideoxy-5-Amino Hexoses from Non-Carbohydrate Precursors
Autor: Giuseppe Pedrocchi-Fantoni, Daniela Faiardi, Domenica Pizzi, Giovanni Fronza, Claudio Fuganti
Publikováno v: Journal of Carbohydrate Chemistry. 8:469-483
The D-lyxo and D-ribo methyl-N-trifluoroacetyl-2,5,6-trideoxy-5-amino hexofuranosides (13) and (14) are accessible from carbohydrate-like acyclic C7 products 3 and 5, whereas the 3-C-methyl analog of 13 is prepared in similar way from 15. Azide treat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fa51d1c675f3b3a447d108e1403cc2df
https://doi.org/10.1080/07328308908048575
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5
ChemInform Abstract: Phenylacetyloxymethylene, a Carboxyl Protecting Group Removable with Immobilized Penicillin Acylase, Useful in Benzyl Penicillin Chemistry
Autor: Eva Baldaro, Piero Grasselli, Ameriga Lazzarini, Claudio Fuganti, Daniela Faiardi
Publikováno v: ChemInform. 20
The phenylacetyloxymethylene group serves to protect the carboxyl group of benzylpenicillin sulphoxide (2a) during the transformation into 7-ADCA and 7β-amino-3-methoxyceph-3-em-4-carboxylic acid (9), being removed together with the 7-phenylacetyl s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::30a5a34b8cc36cb452d4b5525ec43705
https://doi.org/10.1002/chin.198910349
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7
Phenylacetyloxymethylene, a carboxyl protecting group removable with immobilized penicillin acylase, useful in benzyl penicillin chemistry
Autor: Piero Grasselli, Ameriga Lazzarini, Eva Baldaro, Claudio Fuganti, Daniela Faiardi
Publikováno v: Tetrahedron Letters. 29:4623-4624
The phenylacetyloxymethylene group serves to protect the carboxyl group of benzylpenicillin sulphoxide (2a) during the transformation into 7-ADCA and 7β-amino-3-methoxyceph-3-em-4-carboxylic acid (9), being removed together with the 7-phenylacetyl s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9219f75bec56d26d7ea546e7bda644ed
https://doi.org/10.1016/s0040-4039(00)80564-x
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