Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Daniela F. P. Leite"'
Autor:
Rafael C Dutra, Daniela F P Leite, Allisson F Bento, Marianne N Manjavachi, Eliziane S Patrício, Cláudia P Figueiredo, João B Pesquero, João B Calixto
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27875 (2011)
BackgroundMultiple sclerosis (MS) is a demyelinating and neuroinflammatory disease of the human central nervous system (CNS). The expression of kinins is increased in MS patients, but the underlying mechanisms by which the kinin receptor regulates MS
Externí odkaz:
https://doaj.org/article/6c2cc222a84b4e4b8ffac7b3db76244f
Autor:
Allisson Freire Bento, João B. Calixto, Daniela F. P. Leite, Rafael C. Dutra, Maíra A. Bicca, Rodrigo Marcon
Publikováno v:
The Journal of Immunology. 191:4288-4298
It has been previously reported that dietary fish oils, which are rich in the polyunsaturated fatty acids eicosapentaenoic acid and docosahexaenoic acid, can exert beneficial effects in inflammatory bowel disease. In this study, we investigated the e
Autor:
Maíra A. Bicca, João Bosco Pesquero, Rafael C. Dutra, João B. Calixto, Marianne N. Manjavachi, Allisson Freire Bento, Rodrigo Marcon, Daniela F. P. Leite
Publikováno v:
Neurobiology of Disease, Vol 54, Iss, Pp 82-93 (2013)
Multiple sclerosis (MS) is a progressive, demyelinating inflammatory disease of the human central nervous system (CNS). While the primary symptoms of MS affect motor function, it is now recognized that chronic pain is a relevant symptom that affects
Autor:
Eliane Maria Goldfeder, Nelson M. Vaz, Cláudia R. Carvalho, Gustavo Campos Ramos, Daniela F. P. Leite, Silvia DalBó, Jamil Assreuy
Publikováno v:
Autoimmunity. 45:233-244
Following a myocardial infarction, lymphocytes have been suggested to react with the damaged heart tissue, which can impair proper tissue healing. In the present work, we investigate whether ingestion of a myocardial homogenate and the consequent dev
Autor:
Daniela F. P. Leite, Edinéia L. Andrade, Janice Koepp, Allisson Freire Bento, João B. Calixto, Marcos Antônio Dias, Paulo César Leal, Stefânia Forner
Publikováno v:
American Journal of Physiology-Renal Physiology. 300:F1223-F1234
The ankyrin-repeat transient receptor potential 1 (TRPA1) has been implicated in pathological conditions of the bladder, but its role in overactive bladder (OAB) following spinal cord injury (SCI) remains unknown. In this study, using a rat SCI model
Autor:
Alexandre de Paula Rogerio, Cláudia P. Figueiredo, Daniela F. P. Leite, Edinéia L. Andrade, João B. Calixto
Publikováno v:
British Journal of Pharmacology. 158:1074-1087
Background and purpose: α-Humulene and trans-caryophyllene are plant sesquiterpenes with pronounced anti-inflammatory properties. Here, we evaluated the effects of these compounds in an experimental model of airways allergic inflammation. Experiment
Autor:
Juliana Echevarria-Lima, Samira Cardoso Ferreira, Daniela F. P. Leite, João B. Calixto, Vivian M. Rumjanek
Publikováno v:
Journal of Leukocyte Biology. 82:630-637
Inflammatory mediators are released from injured tissues being responsible for the first steps of inflammatory processes. Multidrug efflux transporters, members of the ATP-binding cassette (ABC) family, are ubiquitously expressed. ABCC molecules tran
Publikováno v:
Biochemical Pharmacology. 73:665-674
Multidrug resistance related protein 1 (MRP1/ABCC1) is an ABC transporter protein related to the extrusion of reduced glutathione (GSH), oxidized glutathione (GSSG) and GSH-conjugates, as well as leukotriene C(4) and cyclopentane prostaglandins. Inhi
The Cytotoxic Effect and the Multidrug Resistance Reversing Action of Lignans fromPhyllanthus amarus
Autor:
Daniela F. P. Leite, Vera Lúcia Garcia Rehder, Vivian M. Rumjanek, Lucilia V. de Melo, Tânia Longo Mazzuco, João B. Calixto, Aline Silvestre, Cândida Aparecida Leite Kassuya
Publikováno v:
Planta Medica. 72:1353-1358
Multidrug resistance (MDR) constitutes the major obstacle to the successful treatment of cancer. In several cancer cells, MDR is thought to be mediated by the super-expression of P-glycoprotein (Pgp). Pgp extrudes drugs from the cells, therefore redu
Autor:
Daniela F. P. Leite, Cândida Aparecida Leite Kassuya, Lucilia V. de Melo, João B. Calixto, Vera Lúcia Garcia Rehder
Publikováno v:
Planta Medica. 71:721-726
This study assessed the anti-inflammatory effect of the extracts and purified lignans obtained from Phyllanthus amarus. Given orally, the hexane extract (HE), the lignan-rich fraction (LRF), or the lignans phyltetralin, nirtetralin, niranthin, but no