Výsledky vyhledávání - "Daniela Ehgartner"

Controlling the specific growth rate via biomass trend regulation in filamentous fungi bioprocesses

Autor: Daniela Ehgartner, Julian Kager, Sarah Heinzl, Manuela Frank, Jens Fricke, Christoph Herwig, Thomas Hartmann, Lukas Veiter

Publikováno v: Chemical Engineering Science. 172:32-41

Increasing pressure on product quality and quantity pushes solutions of process control to be a central issue in pharmaceutical bioprocesses. Especially online biomass estimation, and further control of the specific growth rate are of central importa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2a9894c80636cf65ede742b8525e4813
https://doi.org/10.1016/j.ces.2017.06.020

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Toward a Noninvasive, Label-Free Screening Method for Determining Spore Inoculum Quality of Penicillium chrysogenum Using Raman Spectroscopy

Autor: Julia Kuligowski, Cosima Koch, Karin Wieland, Bernhard Lendl, Georg Ramer, Johannes Ofner, Christoph Herwig, Daniela Ehgartner

Publikováno v: Applied Spectroscopy. 71:2661-2669

We report on a label-free, noninvasive method for determination of spore inoculum quality of Penicillium chrysogenum prior to cultivation/germination. Raman microspectroscopy providing direct, molecule-specific information was used to extract informa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af78906f9ecc519424c8bfc6287410c6
https://doi.org/10.1177/0003702817727728

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Morphological analysis of the filamentous fungus Penicillium chrysogenum using flow cytometry—the fast alternative to microscopic image analysis

Autor: Christoph Herwig, Jens Fricke, Daniela Ehgartner

Publikováno v: Applied Microbiology and Biotechnology

An important parameter in filamentous bioreactor cultivations is the morphology of the fungi, due to its interlink to productivity and its dependency on process conditions. Filamentous fungi show a large variety of morphological forms in submerged cu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eec009d36a8d7d85a83ebc858a6fea6
https://doi.org/10.1007/s00253-017-8475-2

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At-line determining spore germination of Penicillium chrysogenum bioprocesses in complex media

Autor: A. Schroder, Jens Fricke, Daniela Ehgartner, Christoph Herwig

Publikováno v: Applied Microbiology and Biotechnology

Spore inoculum quality in filamentous bioprocesses is a critical parameter associated with viable spore concentration (1) and spore germination (2). It influences pellet morphology and, consequently, process performance. The state-of-the-art method t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da1e8e2bbf3b17e97fb025b9fddf69c8
https://doi.org/10.1007/s00253-016-7787-y

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At-line determination of spore inoculum quality in Penicillium chrysogenum bioprocesses

Autor: Lukas Neutsch, Christoph Herwig, Daniela Ehgartner

Publikováno v: Applied Microbiology and Biotechnology. 100:5363-5373

Spore inoculum quality in filamentous bioprocesses is a critical parameter influencing pellet morphology and, consequently, process performance. It is essential to determine the concentration of viable spores before inoculation, to implement quality

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::363977b9678333ff62bb6d7a7d39ecdb
https://doi.org/10.1007/s00253-016-7319-9

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A novel real-time method to estimate volumetric mass biodensity based on the combination of dielectric spectroscopy and soft-sensors

Autor: Daniela Ehgartner, Christoph Herwig, Patrick Sagmeister, Patrick Wechselberger

Publikováno v: Journal of Chemical Technology & Biotechnology. 90:262-272

BACKGROUND The PAT initiative encourages designing, analyzing, and controlling manufacturing through timely measurements. Dielectric measurements and first principle soft-sensors emerged as valuable real-time bioprocess analytical PAT tools to improv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::053b746e946c35dfe701ae178157d7ce
https://doi.org/10.1002/jctb.4469

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A novel method to recover inclusion body protein from recombinant E. coli fed-batch processes based on phage ΦX174-derived lysis protein E

Autor: Timo Langemann, Patrick Sagmeister, Daniela Ehgartner, Christoph Herwig, Andrea Meitz, Werner Lubitz

Publikováno v: Applied Microbiology and Biotechnology

Production of recombinant proteins as inclusion bodies is an important strategy in the production of technical enzymes and biopharmaceutical products. So far, protein from inclusion bodies has been recovered from the cell factory through mechanical o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b6b60dd36afa44ae4178d6c434457b0
https://pubmed.ncbi.nlm.nih.gov/28429059

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Imaging Flow Cytometry and High-Throughput Microscopy for Automated Macroscopic Morphological Analysis of Filamentous Fungi

Autor: Aydin Golabgir, Peter Sagmeister, Andreas E. Posch, Daniela Ehgartner, Christoph Herwig, Lukas Neutsch

Publikováno v: Fungal Biology ISBN: 9783319105024

Traditional methods for automated and high-throughput morphological analysis of filamentous fungi can be time-consuming and difficult. Here, two suitable image acquisition methods and subsequent image and data processing steps are presented. The acqu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c1089cf0ec553372ba68c1b80f03e06a
https://doi.org/10.1007/978-3-319-10503-1_17

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