Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Daniela Egli-Spichtig"'
Autor:
Daniela Egli-Spichtig, Martin Y. H. Zhang, Alfred Li, Eva Maria Pastor Arroyo, Nati Hernando, Carsten A. Wagner, Wenhan Chang, Farzana Perwad
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Fibroblast growth factor 23 (FGF23) is a bone-derived endocrine hormone that regulates phosphate and vitamin D metabolism. In models of FGF23 excess, renal deoxyribonuclease 1 (Dnase1) mRNA expression is downregulated. Dnase-1 is an endonucl
Externí odkaz:
https://doaj.org/article/89d7811941be4841a8aed0d4f045fe9c
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Fibroblast growth factor 23 (FGF23) regulates phosphate homeostasis and vitamin D metabolism. In patients with acute kidney injury (AKI), FGF23 levels rise rapidly after onset of AKI and are associated with AKI progression and increased mortality. In
Externí odkaz:
https://doaj.org/article/78508e89fbcf46e5904586120b19b19d
Autor:
Daniela Egli-Spichtig, Ahmad Kamal Hamid, Eva Maria Pastor Arroyo, Markus Ketteler, Andrzej Wiecek, Alexander R Rosenkranz, Andreas Pasch, Horst Lorenz, Burkhard Hellmann, Michael Karus, Richard Ammer, Isabel Rubio-Aliaga, Carsten A Wagner
Publikováno v:
Clinical Kidney Journal.
Background Hyperphosphatemia is associated with increased mortality and cardiovascular morbidity of end-stage kidney failure (ESKF) patients. Managing serum phosphate in ESKF patients is challenging and mostly based on limiting intestinal phosphate a
Autor:
Eva Maria Pastor Arroyo, Carsten A. Wagner, Wenhan Chang, Nati Hernando, Martin Y. H. Zhang, Daniela Egli-Spichtig, Alfred Li, Farzana Perwad
Publikováno v:
Scientific reports, vol 11, iss 1
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Fibroblast growth factor 23 (FGF23) is a bone-derived endocrine hormone that regulates phosphate and vitamin D metabolism. In models of FGF23 excess, renal deoxyribonuclease 1 (Dnase1) mRNA expression is downregulated. Dnase-1 is an endonuclease whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c523826eb73fabd70f88646acbef2e46
https://escholarship.org/uc/item/3418f2jb
https://escholarship.org/uc/item/3418f2jb
Publikováno v:
Clinical Science (London, England : 1979)
Dietary habits in the western world lead to increasing phosphate intake. Under physiological conditions, extraosseous precipitation of phosphate with calcium is prevented by a mineral buffering system composed of calcification inhibitors and tight co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::def1d358dbc93e97c3174b7a091e62a8
https://doi.org/10.5167/uzh-203278
https://doi.org/10.5167/uzh-203278
Autor:
Farah Al Sabie, Justine Bacchetta, Vincent Brandenburg, Ming Chang Hu, Chang Huei Chen, Lingfeng Chen, Erica L. Clinkenbeard, Michael J. Econs, Daniela Egli-Spichtig, Reinhold G. Erben, Sarah Erem, Carlos C. Faraco, Seiji Fukumoto, Regina Goetz, Alexander Grabner, Dieter Haffner, Mark R. Hanudel, Ping He, Gunnar H. Heine, Martin Hewison, Jan-Luuk Hillebrands, Keith A. Hruska, Chou-Long Huang, Erik A. Imel, Anna Jovanovich, Stefanie Krick, Makoto Kuro-o, Seong Min Lee, Maren Leifheit-Nestler, Rik Mencke, Orson W. Moe, Moosa Mohammadi, John Musgrove, Javier A. Neyra, Hannes Olauson, Katherine Wesseling Perry, Farzana Perwad, J. Wesley Pike, Mohammed S. Razzaque, Beatrice Richter, Isidro B. Salusky, Renal Section, Sarah Seiler-Mußler, Taylor Struemph, Marc G. Vervloet, Curtis Vrabec, Matthew J. Williams, Clinton B. Wright, Allen Zinkle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40c13d3f4e067b721f26d0665211b969
https://doi.org/10.1016/b978-0-12-818036-5.01002-8
https://doi.org/10.1016/b978-0-12-818036-5.01002-8
Autor:
Daniela Egli-Spichtig, Farzana Perwad
Canonical fibroblast growth factor 23 (FGF23) signaling requires FGF receptors (FGFRs), α-Klotho, and heparan sulfate (HS). Dimerization of two stable FGF23–FGFR–Klotho–HS quaternary signaling complexes is necessary to induce signal activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f006c863287fa3d571708f803957d02d
https://doi.org/10.1016/b978-0-12-818036-5.00008-2
https://doi.org/10.1016/b978-0-12-818036-5.00008-2
Autor:
Rachel I. Gafni, Lori C. Guthrie, Peter D. Burbelo, Michael J. Econs, Farzana Perwad, Michael T. Collins, Shoji Ichikawa, Daniela Egli-Spichtig, Emily G. Farrow, Christopher J. Romero, Mary Scott Roberts
Publikováno v:
Journal of Clinical Investigation. 128:5368-5373
Hyperphosphatemic familial tumoral calcinosis (HFTC)/hyperostosis-hyperphosphatemia syndrome (HHS) is an autosomal recessive disorder of ectopic calcification due to deficiency of or resistance to intact fibroblast growth factor 23 (iFGF23). Inactiva
Autor:
Benjamin Misselwitz, Carsten A. Wagner, Roland H. Wenger, Michael Föller, V Virginia Ballotta, Murielle Bochud, Menno Pruijm, Isabelle Frey-Wagner, Carla Bettoni, Michal Rajski, Farzana Perwad, Pedro Henrique Imenez Silva, Sandra Hofmann, Gerhard Rogler, Alexander Benedikt Leichtle, Nicole Gehring, David Hoogewijs, Daniel Ackermann, Felix Knauf, Eva María Pastor-Arroyo, Belen Ponte, Daniela Egli-Spichtig, Ian J. Frew, Georg-Martin Fiedler, Florian Lang, Désirée Schönenberger, Martin Y. H. Zhang, Bob Glaudemans
Publikováno v:
Kidney International, 96(4), 890-905. Nature Publishing Group
Fibroblast growth factor 23 (FGF23) regulates phosphate homeostasis, and its early rise in patients with chronic kidney disease is independently associated with all-cause mortality. Since inflammation is characteristic of chronic kidney disease and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c982e566d66de8f2c28191a073770512
https://research.tue.nl/nl/publications/c463742e-2c74-4c59-863d-d45e8494808c
https://research.tue.nl/nl/publications/c463742e-2c74-4c59-863d-d45e8494808c