Zobrazeno 1 - 10
of 202
pro vyhledávání: '"Daniela D. Weber"'
Autor:
Joana Pereira-Vieira, Daniela D. Weber, Sâmia Silva, Catarina Barbosa-Matos, Sara Granja, Rui Manuel Reis, Odília Queirós, Young H. Ko, Barbara Kofler, Margarida Casal, Fátima Baltazar
Publikováno v:
Pharmaceutics, Vol 16, Iss 4, p 442 (2024)
Altered glycolytic metabolism has been associated with chemoresistance in acute myeloid leukemia (AML). However, there are still aspects that need clarification, as well as how to explore these metabolic alterations in therapy. In the present study,
Externí odkaz:
https://doaj.org/article/978b0580ff9f484ba50936c5618b828f
Publikováno v:
Molecular Metabolism, Vol 75, Iss , Pp 101771- (2023)
Background: Neuroblastoma is a paediatric malignancy of incredibly complex aetiology. Oncogenic protein kinase signalling in neuroblastoma has conventionally focussed on transduction through the well-characterised PI3K/Akt and MAPK pathways, in which
Externí odkaz:
https://doaj.org/article/6c4ddf5ffa4743768a880078bd8b47a6
Autor:
Daniela D. Weber, Sepideh Aminzadeh-Gohari, Maheshwor Thapa, Anna-Sophia Redtenbacher, Luca Catalano, Tânia Capelôa, Thibaut Vazeille, Michael Emberger, Thomas K. Felder, René G. Feichtinger, Peter Koelblinger, Guido Dallmann, Pierre Sonveaux, Roland Lang, Barbara Kofler
Publikováno v:
Cancer & Metabolism, Vol 10, Iss 1, Pp 1-20 (2022)
Abstract Background Growing evidence supports the use of low-carbohydrate/high-fat ketogenic diets as an adjunctive cancer therapy. However, it is unclear which genetic, metabolic, or immunological factors contribute to the beneficial effect of ketog
Externí odkaz:
https://doaj.org/article/2d1d742289f44a19bbc1d95c27545516
Autor:
Luca Catalano, Sepideh Aminzadeh-Gohari, Daniela D. Weber, Rodolphe Poupardin, Victoria E. Stefan, William J. Smiles, Julia Tevini, René G. Feichtinger, Sophia Derdak, Martin Bilban, Stefan Bareswill, Markus M. Heimesaat, Barbara Kofler
Publikováno v:
Metabolites, Vol 13, Iss 8, p 910 (2023)
Neuroblastoma (NB) is a childhood cancer in which amplification of the MYCN gene is the most acknowledged marker of poor prognosis. MYCN-amplified NB cells rely on both glycolysis and mitochondrial oxidative phosphorylation (OXPHOS) for energy produc
Externí odkaz:
https://doaj.org/article/fcee0e7036e44b97ab747e0b8b617e5e
Autor:
Daniela D. Weber, Sepideh Aminzadeh-Gohari, Julia Tulipan, Luca Catalano, René G. Feichtinger, Barbara Kofler
Publikováno v:
Molecular Metabolism, Vol 33, Iss , Pp 102-121 (2020)
Background: Cancer is one of the greatest public health challenges worldwide, and we still lack complementary approaches to significantly enhance the efficacy of standard anticancer therapies. The ketogenic diet, a high-fat, low-carbohydrate diet wit
Externí odkaz:
https://doaj.org/article/60845d6dfdf04e6dab794674c799c186
Autor:
Daniela D. Weber, Maheshwor Thapa, Sepideh Aminzadeh-Gohari, Anna-Sophia Redtenbacher, Luca Catalano, René G. Feichtinger, Peter Koelblinger, Guido Dallmann, Michael Emberger, Barbara Kofler, Roland Lang
Publikováno v:
Cancers, Vol 13, Iss 3, p 434 (2021)
Melanomas are genetically and metabolically heterogeneous, which influences therapeutic efficacy and contributes to the development of treatment resistance in patients with metastatic disease. Metabolite phenotyping helps to better understand complex
Externí odkaz:
https://doaj.org/article/aac84f8cd9944c2683d62b225935a852
Autor:
Sepideh Aminzadeh-Gohari, Daniela D. Weber, Luca Catalano, René G. Feichtinger, Barbara Kofler, Roland Lang
Publikováno v:
Biomolecules, Vol 10, Iss 10, p 1395 (2020)
Drastically elevated glycolytic activity is a prominent metabolic feature of cancer cells. Until recently it was thought that tumor cells shift their entire energy production from oxidative phosphorylation (OXPHOS) to glycolysis. However, new evidenc
Externí odkaz:
https://doaj.org/article/e7a7beaf96f44480b2b6162699ad0289
Autor:
Hannelore Daniel, Britta Spanier, Verena Schlagbauer, Thomas Hofmann, Roman Lang, Tatjana Lang, Anica Lechner, Tizia Thoma, Daniela D. Weber, Katrin Petzold, Anja Beusch, Markus Bösl, Marion Rothner
Publikováno v:
Journal of Agricultural and Food Chemistry. 67:4774-4781
Targeted analysis of Coffea arabica and Coffea canephora green coffees (total sample size n = 57) confirmed 2-O-β-d-glucopyranosyl-carboxyatractyligenin (6) as the quantitatively dominating carboxyatractyligenin derivative. Its abundance in Arabicas
Autor:
Michael Emberger, Sepideh Aminzadeh-Gohari, Guido Dallmann, Maheshwor Thapa, Peter Koelblinger, René G. Feichtinger, Daniela D. Weber, Barbara Kofler, Anna-Sophia Redtenbacher, Luca Catalano, Roland Lang
Publikováno v:
Cancers, Vol 13, Iss 434, p 434 (2021)
Cancers
Volume 13
Issue 3
Cancers
Volume 13
Issue 3
Simple Summary Studying the metabolome, the complete set of metabolites found in a biological sample, helps to understand how metabolism differs between healthy and diseased individuals. Malignant skin cancers (melanomas) differ greatly in their muta
Autor:
Sepideh Aminzadeh-Gohari, Julia Tulipan, Barbara Kofler, Luca Catalano, Daniela D. Weber, René G. Feichtinger
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 33, Iss, Pp 102-121 (2020)
Molecular Metabolism, Vol 33, Iss, Pp 102-121 (2020)
Background Cancer is one of the greatest public health challenges worldwide, and we still lack complementary approaches to significantly enhance the efficacy of standard anticancer therapies. The ketogenic diet, a high-fat, low-carbohydrate diet with