Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Daniela D. Vargens"'
Autor:
Guilherme Suarez-Kurtz, Daniela D Vargens, Ana Beatriz Santoro, Mara H Hutz, Maria Elisabete de Moraes, Sérgio D J Pena, Ândrea Ribeiro-dos-Santos, Marco A Romano-Silva, Claudio José Struchiner
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e83472 (2014)
The influence of self-reported "race/color", geographical origin and genetic ancestry on the distribution of three functional CYP3A5 polymorphisms, their imputed haplotypes and inferred phenotypes was examined in 909 healthy, adult Brazilians, self-i
Externí odkaz:
https://doaj.org/article/2477138d92774fe38c50b8d69ae2e214
Autor:
Ana Beatriz Santoro, Ronaldo R. S. Neves, Ricardo M. R. Meirelles, Daniel Bulzico, Guilherme Suarez-Kurtz, Daniela D. Vargens, Daniela Polessa Paula, Luiz Paulo Kowalski, Mateus de Camargo Barros Filho, Claudio J. Struchine, Cencita H. C. N. Pessoa
Publikováno v:
British Journal of Clinical Pharmacology. 78:1067-1075
Aim To evaluate the impact of genetic polymorphisms in uridine 5′-glucuronosylytansferases UGT1A1 and UGT1A3 and iodothyronine-deiodinases types 1 and 2 on levothyroxine (T4; 3,5,3′,5′-triiodo-L-thyronine) dose requirement for suppression of th
Publikováno v:
Pharmacogenomics. 13:851-854
1Divisao de Farmacologia, Coordenacao de Pesquisa, Instituto Nacional de Câncer, Rio de Janeiro, RJ 20231-050, Brazil 2Departamento de Genetica, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil *Author for correspondence: Tel.: +5
Autor:
Guilherme, Suarez-Kurtz, Vinicius A, Sortica, Daniela D, Vargens, Estela M, Bruxel, Maria-Luiza, Petzl-Erler, Maria-Luiza, Petz-Erler, Luisa T, Tsuneto, Mara H, Hutz
Publikováno v:
Pharmacogenetics and Genomics. 22:305-309
A novel NAT2 tagSNP (rs1495741) and a 2-SNP genotype (rs1041983 and rs1801280) have been recently shown to accurately predict the NAT2 acetylator phenotypes in populations of exclusive or predominant European/White ancestry. We confirmed the accuracy
Autor:
Guilherme Suarez-Kurtz, Daniela D. Vargens, D. Teixeira, A. Príncipe, Elisabete Oliveira, António Amorim, Maria João Prata
Publikováno v:
Brazilian Journal of Medical and Biological Research. 43:677-680
A 3-bp insertion/deletion polymorphism in intron 6 of GSTM3 (rs1799735, GSTM3*A/*B) affects the activity of the phase 2 xenobiotic metabolizing enzyme GSTM3 and has been associated with increased cancer risk. The GSTM3*B allele is rare or absent in S
Publikováno v:
European Journal of Clinical Pharmacology. 64:253-256
To describe the impact of population admixture on the distribution of the GNB3 825CT polymorphism in the heterogeneous Brazilian population.Individual DNA from 236 healthy Brazilians, self-identified as White, Intermediate and Black, was genotyped fo
Autor:
Mara H. Hutz, Marco Aurélio Romano-Silva, Sérgio D.J. Pena, Claudio J. Struchiner, Ana Beatriz Santoro, Daniela D. Vargens, Maria Elisabete de Moraes, Guilherme Suarez-Kurtz, Ândrea Ribeiro-dos-Santos
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 1, p e83472 (2014)
PLoS ONE, Vol 9, Iss 1, p e83472 (2014)
The influence of self-reported "race/color", geographical origin and genetic ancestry on the distribution of three functional CYP3A5 polymorphisms, their imputed haplotypes and inferred phenotypes was examined in 909 healthy, adult Brazilians, self-i
Publikováno v:
Basicclinical pharmacologytoxicology. 110(4)
Publikováno v:
Pharmacogenomics. 12(6)
Autor:
Carolina Martins do Prado, Elida B. Ojopi, Ronaldo R. S. Neves, Ricardo M. R. Meirelles, Vera L.G. Leal, Guilherme Suarez-Kurtz, Daniela D. Vargens, Pedro A. Gonçalves, Cencita H. C. N. Pessoa, Daniel Bulzico
Publikováno v:
Pharmacogenetics and genomics. 21(6)
There is a considerable interindividual variation in L-thyroxine [3,5,3',5'-tetraiodo-l-thyronine (T 4 )] dose required for thyrotropin (thyroid-stimulating hormone) suppression in patients with differentiated thyroid cancer. To investigate whether u