Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Daniela Cipolletta"'
Autor:
Jeffrey A. Engelman, Catherine Anne Sabatos-Peyton, Adam S. Crystal, Scott Cameron, Viviana Cremasco, Sonia Quaratino, Philip Gotwals, Becker Hewes, Glenn Dranoff, Daniela Cipolletta, Britta Mueller, Lilli Petruzzelli
Publikováno v:
Nature Reviews Cancer. 17:286-301
Over the past 25 years, research in cancer therapeutics has largely focused on two distinct lines of enquiry. In one approach, efforts to understand the underlying cell-autonomous, genetic drivers of tumorigenesis have led to the development of clini
Autor:
Christophe Benoist, Nicholas J. Van Panhuys, Dmitriy Kolodin, Angela Magnuson, Chaoran Li, Amy J. Wagers, Ronald N. Germain, Diane Mathis, Christine M. Miller, Daniela Cipolletta
Publikováno v:
Cell Metabolism. 21:543-557
Summary A unique population of Foxp3 + CD4 + regulatory T (Treg) cells, with a distinct transcriptome and antigen-receptor repertoire, resides in visceral adipose tissue (VAT) of lean individuals. These cells regulate local inflammation and both loca
Publikováno v:
Proceedings of the National Academy of Sciences. 112:482-487
A unique population of Foxp3(+)CD4(+) regulatory T (Treg) cells resides in visceral adipose tissue (VAT) of lean mice, especially in the epididymal fat depot. VAT Tregs are unusual in their very high representation within the CD4(+) T-cell compartmen
Autor:
Jongsoon Lee, Daniela Cipolletta, Steven E. Shoelson, Christophe Benoist, Amy Li, Markus Feuerer, Diane Mathis, Nozomu Kamei
Publikováno v:
Nature. 486:549-553
Obesity and type-2 diabetes have increased markedly over the past few decades, in parallel. One of the major links between these two disorders is chronic, low-grade inflammation. Prolonged nutrient excess promotes the accumulation and activation of l
Autor:
Maria Pia Cinelli, Teresa Iuvone, Rosa Carnuccio, Daniela De Stefano, Daniela Cipolletta, Gianfranco Tajana, Lorenzo Galluzzi, Maria Chiara Maiuri, Giancarlo Nicolaus
Publikováno v:
Journal of Molecular Medicine. 87:481-492
Several diseases are characterized by chronic inflammation, a condition frequently associated with angiogenesis and fibrogenesis that account for the development of granulation tissue. Nuclear Factor kappa-light-chain-enhancer of activated B cells (N
Autor:
Daniela Cipolletta
Publikováno v:
Immunology. 142(4)
Foxp3(+) CD4(+) regulatory T (Treg) cells, recognized to be one of the most important defences of the human body against an inappropriate immune response, have recently gained attention from those outside immunology thanks to the compelling evidence
Publikováno v:
Seminars in immunology. 23(6)
Foxp3+CD4+ regulatory T (T(reg)) cells are a key population in controlling the immune response. Recently, their roles have been expanded to broader, non-immune, contexts, in particular the metabolic consequences downstream of obesity-induced inflamma
Autor:
Christophe Benoist, Allison B. Goldfine, Jongsoon Lee, Daniela Cipolletta, Diane Mathis, Ali Nayer, Steven E. Shoelson, Markus Feuerer, Laura Herrero, Jamie Wong, Afia Naaz
Obesity is accompanied by chronic, low-grade inflammation of adipose tissue, which promotes insulin resistance and type-2 diabetes. How does fat inflammation escape the powerful armamentarium of cells and molecules normally responsible for guarding a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::725441c14a5d6b0cfc917932911b4541
https://europepmc.org/articles/PMC3115752/
https://europepmc.org/articles/PMC3115752/
Autor:
Li Li, Daniela Cipolletta, Christophe Benoist, Junko Nishio, Alexander Y. Rudensky, Diane Mathis, Jaime Darce, Dipayan Rudra
Publikováno v:
Immunity. (5):731-741
SummaryMaintenance of lymphoid homeostasis in a number of immunological and inflammatory contexts is served by a variety of regulatory T (Treg) cell subtypes and depends on interaction of the transcription factor FoxP3 with specific transcriptional c