Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Daniela Cederfelt"'
Autor:
Daniela Cederfelt, Dilip Badgujar, Ayan Au Musse, Bernhard Lohkamp, U. Helena Danielson, Doreen Dobritzsch
Publikováno v:
Biomolecules, Vol 13, Iss 12, p 1763 (2023)
The activity of β-ureidopropionase, which catalyses the last step in the degradation of uracil, thymine, and analogous antimetabolites, is cooperatively regulated by the substrate and product of the reaction. This involves shifts in the equilibrium
Externí odkaz:
https://doaj.org/article/b1ca3c457cbe4892b9e70fd103dea448
Autor:
Marco Daniele Parenti, Marina Naldi, Elisabetta Manoni, Edoardo Fabini, Daniela Cederfelt, Vladimir O. Talibov, Valeria Gressani, Ummu Guven, Valentina Grossi, Candida Fasano, Paola Sanese, Katia De Marco, Alexander A. Shtil, Alexander V. Kurkin, Andrea Altieri, U. Helena Danielson, Giuseppina Caretti, Cristiano Simone, Greta Varchi, Manuela Bartolini, Alberto Del Rio
Publikováno v:
European journal of medicinal chemistry. 243
Recent findings support the hypothesis that inhibition of SMYD3 methyltransferase may be a therapeutic avenue for some of the deadliest cancer types. Herein, active site-selective covalent SMYD3 inhibitors were designed by introducing an appropriate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79a814780204b0edafb3744ad3e41788
https://pubmed.ncbi.nlm.nih.gov/36116234
https://pubmed.ncbi.nlm.nih.gov/36116234
Autor:
Ben Davis, Giulia Opassi, Darius Vagrys, U. Helena Danielson, Iwan J. P. de Esch, Anna Moberg, P. Boronat, Roderick E. Hubbard, Doreen Dobritzsch, Claes Holmgren, Jacqueline E. van Muijlwijk-Koezen, David J. Hamilton, Edward A. FitzGerald, Peter O'Brien, Daniela Cederfelt, Hanna F. Klein, Maikel Wijtmans, Vladimir O. Talibov, Mia Abramsson, Maria T. Lindgren
Publikováno v:
bioRxiv, 2020. Cold Spring Harbor Laboratory Press
Fitzgerald, E, Hamilton, D, Boronat, P, van Muijlwijk-Koezen, J E, Wijtmans, M, de Esch, IJP & Danielson, H 2020, ' Multiplexed experimental strategies for fragment library screening using SPR biosensors ', bioRxiv, vol. 2020 . https://doi.org/10.1101/2020.12.23.424167
Fitzgerald, E, Hamilton, D, Boronat, P, van Muijlwijk-Koezen, J E, Wijtmans, M, de Esch, IJP & Danielson, H 2020, ' Multiplexed experimental strategies for fragment library screening using SPR biosensors ', bioRxiv, vol. 2020 . https://doi.org/10.1101/2020.12.23.424167
Surface plasmon resonance biosensor technology (SPR) is ideally suited for fragment-based lead discovery. However, generally suitable experimental procedures or detailed protocols are lacking, especially for structurally or physico-chemically challen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7ac1e8fd204791f50bf282acb941200
https://doi.org/10.1101/2020.12.23.424167
https://doi.org/10.1101/2020.12.23.424167
Autor:
Edward A, FitzGerald, Margaret T, Butko, Pierre, Boronat, Daniela, Cederfelt, Mia, Abramsson, Hildur, Ludviksdottir, Jacqueline E, van Muijlwijk-Koezen, Iwan J P, de Esch, Doreen, Dobritzsch, Tracy, Young, U Helena, Danielson
Publikováno v:
RSC advances. 11(13)
Biophysical screening of compound libraries for the identification of ligands that interact with a protein is efficient, but does typically not reveal if (or how) ligands may interfere with its functional properties. For this a biochemical/functional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3ffad0a15c8299db2e7bd6cbc46c99bd
https://pubmed.ncbi.nlm.nih.gov/35423271
https://pubmed.ncbi.nlm.nih.gov/35423271