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pro vyhledávání: '"Daniela C. Lange"'
Publikováno v:
Biophysical Chemistry. 74:45-51
Two potential ligand binding sites in the lipocalin β-lactoglobulin have been postulated for small hydrophobic molecules such as retinol or retinoic acid. An agreement on one of the two alternatives, an interior cavity or a surface cleft, however, h
Publikováno v:
Methods (San Diego, Calif.). 27(4)
The existence of dimers and higher oligomers of G-protein-coupled receptors (GPCRs) has been frequently reported using strategies based on coimmunoprecipitation or Western blot assays. These methods rely on highly artificial systems with overexpresse
Autor:
Daniela C. Lange, Magalie Rocheville, Ujendra Kumar, Yogesh C. Patel, Ramesh C. Patel, Shutish C. Patel
Publikováno v:
Science (New York, N.Y.). 288(5463)
Somatostatin and dopamine are two major neurotransmitter systems that share a number of structural and functional characteristics. Somatostatin receptors and dopamine receptors are colocalized in neuronal subgroups, and somatostatin is involved in mo
Autor:
Ujendra Kumar, Ramesh C. Patel, Daniela C. Lange, Yogesh C. Patel, Magalie Rocheville, Ramakrishnan Sasi
Publikováno v:
The Journal of biological chemistry. 275(11)
The existence of receptor dimers has been proposed for several G protein-coupled receptors. However, the question of whether G protein-coupled receptor dimers are necessary for activating or modulating normal receptor function is unclear. We address