Comparative analysis of neutrophil and monocyte epigenomes

Autor: Rubio M, van Bommel A, Nilofar Sharifi, Alessandra Breschi, David G. Pisano, David J. Richardson, Paul Bertone, Marie-Laure Yaspo, Stephen B. Watt, Emanuele Raineri, de la Torre, Hinri Kerstens, Angelika Merkel, Pancaldi, Gelpí Jl, Emilio Palumbo, Martin Vingron, van der Ent Ma, Joost H.A. Martens, Royo R, Daniel R. Zerbino, Myrto Kostadima, Ian Dunham, Augusto Rendon, Laura Clarke, Sadia Saeed, Gut I, S. Farrow, Dirk S. Paul, Ali Aghajanirefah, Enrique Carrillo-de-Santa-Pau, Valencia A, Love Mi, Kuijpers T, Marc Sultan, Frances Burden, Anna Esteve-Codina, Nicola Foad, Jessica Quintin, Steven P. Wilder, Iotchkova, Remco Loos, Daniela C. Ifrim, Stephan Beck, Simon Heath, Henk Stunnenberg, Daniel Rico, Lu Chen, Roderic Guigó, Torrents D, Kim Berentsen, Gut M, Fernandez Jm, Abhishek Singh, Paul Flicek, Willem H. Ouwehand, Mihai G. Netea, Hans Lehrach, Thomas Lengauer, Kate Downes, Erber W, Christoph Bock, Stamatina Fragkogianni, Franz-Josef Müller, Sarah Djebali, Colin Logie, Anita Kaan, Eva M. Janssen-Megens, Mattia Frontini, Nicole Soranzo, Antony P. Attwood

Neutrophils and monocytes provide a first line of defense against infections as part of the innate immune system. Here we report the integrated analysis of transcriptomic and epigenetic landscapes for circulating monocytes and neutrophils with the ai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::925831726e7be8465ff928b6d8da49bb

Fungal Chitin Induces Trained Immunity in Human Monocytes during Cross-talk of the Host with Saccharomyces cerevisiae

Autor: Marcello Salvatore Lenucci, Shih-Chin Cheng, Noemi Tocci, Vasilis Oikonomou, Tobias Weil, Lisa Rizzetto, Silvia Moretti, Daniela C. Ifrim, Manuel A. S. Santos, Mihai G. Netea, Bastiaan A. Blok, Duccio Cavalieri, Giorgia Renga, Luigina Romani, Jessica Quintin, Carlotta De Filippo

Publikováno v: Journal of Biological Chemistry, 291, 7961-72
The Journal of biological chemistry
291 (2016): 7961–7972. doi:10.1074/jbc.M115.699645
info:cnr-pdr/source/autori:Rizzetto, Lisa; Ifrim, Daniela C.; Moretti, Silvia; Tocci, Noemi; Cheng, Shih Chin; Quintin, Jessica; Renga, Giorgia; Oikonomou, Vasilis; De Filippo, Carlotta; Weil, Tobias; Blok, Bastiaan A.; Lenucci, Marcello S.; Santos, Manuel A.S.; Romani, Luigina; Netea, Mihai G.; Cavalieri, Duccio/titolo:Fungal chitin induces trained immunity in human monocytes during cross-talk of the host with Saccharomyces cerevisiae/doi:10.1074%2Fjbc.M115.699645/rivista:The Journal of biological chemistry (Print)/anno:2016/pagina_da:7961/pagina_a:7972/intervallo_pagine:7961–7972/volume:291
Journal of Biological Chemistry
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology, 2016, 291 (15), pp.7961-7972. ⟨10.1074/jbc.M115.699645⟩
Europe PubMed Central
Journal of Biological Chemistry, 2016, 291 (15), pp.7961-7972. ⟨10.1074/jbc.M115.699645⟩
Journal of Biological Chemistry, 291, 15, pp. 7961-72

This research was originally published in the Journal of Biological Chemistry. Lisa Rizzetto, Daniela C. Ifrim, Silvia Moretti, Noemi Tocci, Shih-Chin Cheng, Jessica Quintin, Giorgia Renga, Vasilis Oikonomou, Carlotta De Filippo, Tobias Weil, Bastiaa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a8113384ac89a682d6c0319c7d85f4e
http://hdl.handle.net/2066/172594

Bacille Calmette-Guerin induces NOD2-dependent nonspecific protection from reinfection via epigenetic reprogramming of monocytes

Autor: Ramnik J. Xavier, Jessica Quintin, Daniela C. Ifrim, Dirk J. de Jong, Joke van Loenhout, Leo A. B. Joosten, Sadia Saeed, Jos W. M. van der Meer, Reinout van Crevel, Cor Jacobs, Johanneke Kleinnijenhuis, Hendrik G. Stunnenberg, Frank Preijers, Mihai G. Netea

Publikováno v: Proceedings of the National Academy of Sciences USA, 109, 17537-17542
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2012, 109 (43), pp.17537-17542. ⟨10.1073/pnas.1202870109⟩
Proceedings of the National Academy of Sciences USA, 109, 43, pp. 17537-17542

Item does not contain fulltext Adaptive features of innate immunity, recently described as "trained immunity," have been documented in plants, invertebrate animals, and mice, but not yet in humans. Here we show that bacille Calmette-Guerin (BCG) vacc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b80c192041b7b9a8c7f326df177634d
https://hdl.handle.net/2066/103888

mTOR- and HIF-1 alpha-mediated aerobic glycolysis as metabolic basis for trained immunity

Autor: Shih-Chin Cheng, Peter M.T. Deen, Hendrik G. Stunnenberg, Joost H.A. Martens, Jessica Quintin, Robert A. Cramer, Kelly M. Shepardson, Sadia Saeed, Rob J.W. Arts, Nagesha Appukudige Rao, Brian M. J. W. van der Veer, Cisca Wijmenga, Yang Li, Colin Logie, Frank L. van de Veerdonk, Ramnik J. Xavier, Ganesh R. Manjeri, Vinod Kumar, Jos W. M. van der Meer, Evangelos J. Giamarellos-Bourboulis, Daniela C. Ifrim, Mihai G. Netea, Luke A. J. O'Neill, Leo A. B. Joosten, Peter H.G.M. Willems, Ali Aghajanirefah, Aylwin Ng

Publikováno v: Science, 345(6204):1250684. AMER ASSOC ADVANCEMENT SCIENCE
Science
Science, American Association for the Advancement of Science, 2014, 345 (6204), pp.1250684-1250684. ⟨10.1126/science.1250684⟩
Science, 345, 6204, pp. 1250684
Science, 345, 1250684

A BLUEPRINT of immune cell development To determine the epigenetic mechanisms that direct blood cells to develop into the many components of our immune system, the BLUEPRINT consortium examined the regulation of DNA and RNA transcription to dissect t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d383e94b86af0e3fcd3ff35a2c9da54c
https://research.rug.nl/en/publications/7e206545-1e9e-401b-afa1-1cbeda610008

Antifungal innate immunity: recognition and inflammatory networks

Autor: Jessica Quintin, Daniela C. Ifrim, Mihai G. Netea, Frank L. van de Veerdonk, Katharina L. Becker

Publikováno v: Seminars in Immunopathology, 37, 2, pp. 107-16
Seminars in Immunopathology, 37, 107-16
Seminars in Immunopathology
Seminars in Immunopathology, Springer Verlag, 2015, 37 (2), pp.107-116. ⟨10.1007/s00281-014-0467-z⟩

Contains fulltext : 154433.pdf (Publisher’s version ) (Closed access) A large variety of fungi are present in the environment, among which a proportion colonizes the human body, usually without causing any harm. However, depending on the host immun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16e1da872e5024dd46ce4aa12e64321d
https://pubmed.ncbi.nlm.nih.gov/25527294