Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Daniela Botolin"'
Autor:
Yun Wang, Moises Torres-Gonzalez, Sasmita Tripathy, Daniela Botolin, Barbara Christian, Donald B. Jump
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 7, Pp 1538-1552 (2008)
Hepatic fatty acid elongase-5 (Elovl-5) plays an important role in long chain monounsaturated and polyunsaturated fatty acid synthesis. Elovl-5 activity is regulated during development, by diet, hormones, and drugs, and in chronic disease. This repor
Externí odkaz:
https://doaj.org/article/4570f682ce8c4d87a26b252bd866132d
Autor:
Yun Wang, Daniela Botolin, Jinghua Xu, Barbara Christian, Ernestine Mitchell, Bolleddula Jayaprakasam, Muraleedharan Nair, Jeffery M. Peters, Julia Busik, L. Karl Olson, Donald B. Jump
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 9, Pp 2028-2041 (2006)
Fatty acid elongases and desaturases play an important role in hepatic and whole body lipid composition. We examined the role that key transcription factors played in the control of hepatic elongase and desaturase expression. Studies with peroxisome
Externí odkaz:
https://doaj.org/article/730b54111298454ba9ae6205ec701e8f
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 1, Pp 181-192 (2006)
Insulin induces and dietary n-3 PUFAs suppress hepatic de novo lipogenesis by controlling sterol-regulatory element binding protein-1 nuclear abundance (nSREBP-1). Our goal was to define the mechanisms involved in this regulatory process. Insulin tre
Externí odkaz:
https://doaj.org/article/232840165df14922b595b32fff6a4940
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 4, Pp 706-715 (2005)
Of the six fatty acid elongase (Elovl) subtypes expressed in mammals, adult rat liver expresses four subtypes: Elovl-5 > Elovl-1 = Elovl-2 = Elovl-6. Overnight starvation and fish oil-enriched diets repressed hepatic elongase activity in livers of ad
Externí odkaz:
https://doaj.org/article/781ffb445795498d9765ee0fc2d0628a
Publikováno v:
Chemistry and Physics of Lipids
Chemistry and Physics of Lipids, Elsevier, 2008, 153, pp.3-13
Chemistry and Physics of Lipids, Elsevier, 2008, 153, pp.3-13
The type and quantity of dietary fat ingested contributes to the onset and progression of chronic diseases, like diabetes and atherosclerosis. The liver plays a central role in whole body lipid metabolism and responds rapidly to changes in dietary fa
Publikováno v:
Food & Nutrition Research; Vol 50, Suppl 2 (2006)-Scandinavian Journal of Food & Nutrition Supplement; 5-12
The type and quantity of dietary fat ingested contributes to the onset and progression of chronic diseases, such as diabetes and atherosclerosis. The liver plays a central role in whole-body lipid metabolism and responds rapidly to changes in dietary
Autor:
Muraleedharan G. Nair, Daniela Botolin, Bolleddula Jayaprakasam, Jinghua Xu, Donald B. Jump, Barbara Christian, Ernestine Mitchell, Jeffrey M. Peters, L. Karl Olson, Yun Wang, Julia V. Busik
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 9, Pp 2028-2041 (2006)
Fatty acid elongases and desaturases play an important role in hepatic and whole body lipid composition. We examined the role that key transcription factors played in the control of hepatic elongase and desaturase expression. Studies with peroxisome
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 1, Pp 181-192 (2006)
Insulin induces and dietary n-3 PUFAs suppress hepatic de novo lipogenesis by controlling sterol-regulatory element binding protein-1 nuclear abundance (nSREBP-1). Our goal was to define the mechanisms involved in this regulatory process. Insulin tre
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 4, Pp 706-715 (2005)
Of the six fatty acid elongase (Elovl) subtypes expressed in mammals, adult rat liver expresses four subtypes: Elovl-5 > Elovl-1 = Elovl-2 = Elovl-6. Overnight starvation and fish oil-enriched diets repressed hepatic elongase activity in livers of ad
Publikováno v:
Journal of Biological Chemistry. 278:40736-40743
Liver X receptors (LXR) alpha and beta play an important role in regulating the expression of genes involved in hepatic bile and fatty acid synthesis, glucose metabolism, as well as sterol efflux. Studies with human embryonic kidney 293 cells indicat