Zobrazeno 1 - 10
of 122
pro vyhledávání: '"Daniela Besozzi a"'
Autor:
Marco Barreca, Matteo Dugo, Barbara Galbardi, Balázs Győrffy, NA-PHER2 consortium, NeoTRIP consortium, Pinuccia Valagussa, Daniela Besozzi, Giuseppe Viale, Giampaolo Bianchini, Luca Gianni, Maurizio Callari
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-11 (2024)
Abstract The prevalence of malignant cells in clinical specimens, or tumour purity, is affected by both intrinsic biological factors and extrinsic sampling bias. Molecular characterization of large clinical cohorts is typically performed on bulk samp
Externí odkaz:
https://doaj.org/article/c48158b1f4944693ad272026d7fa00e8
Autor:
Cirino Botta, Cristina Perez, Marta Larrayoz, Noemi Puig, Maria-Teresa Cedena, Rosalinda Termini, Ibai Goicoechea, Sara Rodriguez, Aintzane Zabaleta, Aitziber Lopez, Sarai Sarvide, Laura Blanco, Daniele M. Papetti, Marco S. Nobile, Daniela Besozzi, Massimo Gentile, Pierpaolo Correale, Sergio Siragusa, Albert Oriol, Maria Esther González-Garcia, Anna Sureda, Felipe de Arriba, Rafael Rios Tamayo, Jose-Maria Moraleda, Mercedes Gironella, Miguel T. Hernandez, Joan Bargay, Luis Palomera, Albert Pérez-Montaña, Hartmut Goldschmidt, Hervé Avet-Loiseau, Aldo Roccaro, Alberto Orfao, Joaquin Martinez-Lopez, Laura Rosiñol, Juan-José Lahuerta, Joan Blade, Maria-Victoria Mateos, Jesús F. San-Miguel, Jose-Angel Martinez Climent, Bruno Paiva, the Programa Para el Estudio de la Terapéutica en Hemopatías Malignas/Grupo Español de Mieloma (PETHEMA/GEM) cooperative group, the iMMunocell study group
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Tumor recognition by T cells is essential for antitumor immunity. A comprehensive characterization of T cell diversity may be key to understanding the success of immunomodulatory drugs and failure of PD-1 blockade in tumors such as multiple
Externí odkaz:
https://doaj.org/article/2de8f8a904e64dd0bd9521c3f7eaa173
Autor:
Daniele M. Papetti, Simone Spolaor, Iman Nazari, Andrea Tirelli, Tommaso Leonardi, Chiara Caprioli, Daniela Besozzi, Thalia Vlachou, Pier Giuseppe Pelicci, Paolo Cazzaniga, Marco S. Nobile
Publikováno v:
Frontiers in Bioinformatics, Vol 3 (2023)
Introduction: Oxford Nanopore Technologies (ONT) is a third generation sequencing approach that allows the analysis of individual, full-length nucleic acids. ONT records the alterations of an ionic current flowing across a nano-scaled pore while a DN
Externí odkaz:
https://doaj.org/article/cfc4ec53880f413b8dcbb9ba447a63aa
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-27 (2021)
Abstract Background Single-cell RNA sequencing (scRNA-Seq) experiments are gaining ground to study the molecular processes that drive normal development as well as the onset of different pathologies. Finding an effective and efficient low-dimensional
Externí odkaz:
https://doaj.org/article/6cfd60949cd545a880f11a39b1f215b0
Autor:
Marco S. Nobile, Federico Fontana, Luca Manzoni, Paolo Cazzaniga, Giancarlo Mauri, Gloria A. A. Saracino, Daniela Besozzi, Fabrizio Gelain
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Self-assembling processes are ubiquitous phenomena that drive the organization and the hierarchical formation of complex molecular systems. The investigation of assembling dynamics, emerging from the interactions among biomolecules like amin
Externí odkaz:
https://doaj.org/article/7d5f7ef478f74696a15526357172f6b7
Autor:
Simone Spolaor, Mattia Rovetta, Marco S. Nobile, Paolo Cazzaniga, Renata Tisi, Daniela Besozzi
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Calcium homeostasis and signaling processes in Saccharomyces cerevisiae, as well as in any eukaryotic organism, depend on various transporters and channels located on both the plasma and intracellular membranes. The activity of these proteins is regu
Externí odkaz:
https://doaj.org/article/bfc503a204064324b7205f598026ea16
Autor:
Paolo Cazzaniga, Maria Raposo, Daniela Besozzi, Ivan Merelli, Antonino Staiano, Angelo Ciaramella, Riccardo Rizzo, Luca Manzoni
Publikováno v:
BMC Bioinformatics, Vol 22, Iss S2, Pp 1-3 (2021)
Externí odkaz:
https://doaj.org/article/6329ed5e810a40da99281827df891db8
Autor:
Andrea Tangherloni, Marco S Nobile, Paolo Cazzaniga, Giulia Capitoli, Simone Spolaor, Leonardo Rundo, Giancarlo Mauri, Daniela Besozzi
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 9, p e1009410 (2021)
Mathematical models of biochemical networks can largely facilitate the comprehension of the mechanisms at the basis of cellular processes, as well as the formulation of hypotheses that can be tested by means of targeted laboratory experiments. Howeve
Externí odkaz:
https://doaj.org/article/c68e42988e454d1fb93c38388c684beb
Autor:
Andrea Tangherloni, Simone Spolaor, Leonardo Rundo, Marco S. Nobile, Paolo Cazzaniga, Giancarlo Mauri, Pietro Liò, Ivan Merelli, Daniela Besozzi
Publikováno v:
BMC Bioinformatics, Vol 20, Iss S4, Pp 1-14 (2019)
Abstract Background In order to fully characterize the genome of an individual, the reconstruction of the two distinct copies of each chromosome, called haplotypes, is essential. The computational problem of inferring the full haplotype of a cell sta
Externí odkaz:
https://doaj.org/article/3a3fab37dad84b53af785205d792e540
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Externí odkaz:
https://doaj.org/article/7cd406e49b2448a79bebd681fc5a8e5f