Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Daniela Begolo"'
Autor:
Daniela Begolo, Isabel M Vincent, Federica Giordani, Ina Pöhner, Michael J Witty, Timothy G Rowan, Zakaria Bengaly, Kirsten Gillingwater, Yvonne Freund, Rebecca C Wade, Michael P Barrett, Christine Clayton
Publikováno v:
PLoS Pathogens, Vol 14, Iss 9, p e1007315 (2018)
Kinetoplastid parasites-trypanosomes and leishmanias-infect millions of humans and cause economically devastating diseases of livestock, and the few existing drugs have serious deficiencies. Benzoxaborole-based compounds are very promising potential
Externí odkaz:
https://doaj.org/article/e1674f3ac3f24f8baaf483e779b5f349
Autor:
Timothy G. Rowan, Federica Giordani, Christine Clayton, Isabel M. Vincent, Zakaria Bengaly, Daniela Begolo, Michael P. Barrett, Yvonne Freund, Kirsten Gillingwater, Michael J. Witty
Kinetoplastid parasites - trypanosomes and leishmanias - infect millions of humans and cause economically devastating diseases of livestock, and the few existing drugs have serious deficiencies. Benzoxaborole-based compounds are very promising potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bafadd72620ecdaf33fd64ec6fc701c7
Publikováno v:
Antimicrobial Agents and Chemotherapy. 58:6260-6264
Elucidation of molecular targets is very important for lead optimization during the drug development process. We describe a direct method to find targets of antitrypanosomal compounds against Trypanosoma brucei using a trypanosome overexpression libr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07ad0f496eba034bb45149c4db538ea5
https://doi.org/10.1128/aac.03338-14
https://doi.org/10.1128/aac.03338-14
Discovery of the Mechanism of Action of Novel Compounds That Target Unicellular Eukaryotic Parasites
Autor:
Daniela Begolo, Christine Clayton
Publikováno v:
Comprehensive Analysis of Parasite Biology: From Metabolism to Drug Discovery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58031b123ff1a12fd132f636d12e022f
https://doi.org/10.1002/9783527694082.ch1
https://doi.org/10.1002/9783527694082.ch1