Concomitant Mutations G12D and G13D on the Exon 2 of the KRAS Gene: Two Cases of Women with Colon Adenocarcinoma

Autor: Elena De Falco, Luca Pacini, Daniela Bastianelli, Gian Paolo Spinelli, Chiara Spoto, Enzo Veltri, Antonella Calogero

Publikováno v: Diagnostics, Vol 11, Iss 4, p 659 (2021)

Colorectal cancer (CRC) is rapidly increasing representing the second most frequent cause of cancer-related deaths. From a clinical-molecular standpoint the therapeutically management of CRC focuses on main alterations found in the RAS family protein

Externí odkaz: https://doaj.org/article/01c489b793a74f5eb110970c661dd477

The transcription factor EGR1 localizes to the nucleolus and is linked to suppression of ribosomal precursor synthesis.

Autor: Donatella Ponti, Gian Carlo Bellenchi, Rosa Puca, Daniela Bastianelli, Marella Maroder, Giuseppe Ragona, Pascal Roussel, Marc Thiry, Dan Mercola, Antonella Calogero

Publikováno v: PLoS ONE, Vol 9, Iss 5, p e96037 (2014)

EGR1 is an immediate early gene with a wide range of activities as transcription factor, spanning from regulation of cell growth to differentiation. Numerous studies show that EGR1 either promotes the proliferation of stimulated cells or suppresses t

Externí odkaz: https://doaj.org/article/02d9463e55d64237a30a0320ecbbcf4d

The adipose tissue of origin influences the biological potential of human adipose stromal cells isolated from mediastinal and subcutaneous fat depots

Autor: Daniela Bastianelli, Ilenia Gatto, Antonella Bordin, Andrea Coccia, Vincenzo Petrozza, Selenia Miglietta, Elena De Falco, Giacomo Frati, Isotta Chimenti, Francesco Cassiano, Camilla Siciliano, Giorgio Mangino, Antonella Calogero, Mohsen Ibrahim

Publikováno v: Stem Cell Research, Vol 17, Iss 2, Pp 342-351 (2016)

Indirect evidence suggests that adipose tissue-derived stromal cells (ASCs) possess different physiological and biological variations related to the anatomical localization of the adipose depots. Accordingly, to investigate the influence of the tissu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7ea1c73c9b5b9c29fb722efc0b94e49
https://pubmed.ncbi.nlm.nih.gov/27614132

Glutamate decarboxylase-dependent acid resistance in Brucella spp.: distribution and contribution to fitness under extremely acidic conditions

Autor: Maria Alessandra Damiano, Daniela Bastianelli, Daniela De Biase, Alessandra Occhialini, Axel Cloeckaert, Sascha Al Dahouk, Stephan Köhler

Publikováno v: Applied and Environmental Microbiology
Applied and Environmental Microbiology, American Society for Microbiology, 2015, 81 (2), pp.578-586. ⟨10.1128/AEM.02928-14⟩

Brucella is an expanding genus of major zoonotic pathogens, including at least 10 genetically very close species occupying a wide range of niches from soil to wildlife, livestock, and humans. Recently, we have shown that in the new species Brucella m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dd703bbab693848394ad0b8a8ca490e
https://pubmed.ncbi.nlm.nih.gov/25381237

The glutamic acid decarboxylase system of the new species Brucella microti contributes to its acid resistance and to oral infection of mice

Autor: Stephan Köhler, Nabil Hanna, Bashir Saadeh, Alessandra Occhialini, María Pilar Jiménez de Bagüés, Daniela De Biase, Daniela Bastianelli

Publikováno v: Journal of Infectious Diseases
Journal of Infectious Diseases, Oxford University Press (OUP), 2012, 206 (9), pp.1424-32. ⟨10.1093/infdis/jis522⟩

BACKGROUND: Genome analysis indicated that the new species Brucella microti possesses a potentially functional glutamate decarboxylase (GAD) system involved in extreme acid resistance in several foodborne bacteria. The contribution of this system in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::748afa3e5defd2f5bb582207406ea756
https://pubmed.ncbi.nlm.nih.gov/22930809