The hydrophilic extract from a new tomato genotype (named DHO) kills cancer cell lines through the modulation of the DNA damage response induced by Campthotecin treatment

Autor: Daniela Barone, Carmelina Antonella Iannuzzi, Iris Maria Forte, Maria Carmen Ragosta, Maria Cuomo, Milena Dell’Aquila, Angela Altieri, Antonella Caporaso, Rosa Camerlingo, Maria Manuela Rigano, Daria Maria Monti, Amalia Barone, Paola Imbimbo, Luigi Frusciante, Marcellino Monda, Margherita D’Angelo, Michelino De Laurentiis, Antonio Giordano, Luigi Alfano

Publikováno v: Frontiers in Oncology, Vol 13 (2023)

IntroductionDNA double-strand breaks are the most toxic lesions repaired through the non-homologous and joining (NHEJ) or the homologous recombination (HR), which is dependent on the generation of single-strand tails, by the DNA end resection mechani

Externí odkaz: https://doaj.org/article/d8120edf9fa24bd2b25af9a7fb9d0a19

Virtual Reality Rehabilitation Systems for Cancer Survivors: A Narrative Review of the Literature

Autor: Antonio Melillo, Andrea Chirico, Giuseppe De Pietro, Luigi Gallo, Giuseppe Caggianese, Daniela Barone, Michelino De Laurentiis, Antonio Giordano

Publikováno v: Cancers (Basel) 14 (2022). doi:10.3390/cancers14133163
info:cnr-pdr/source/autori:Melillo A.; Chirico A.; De Pietro G.; Gallo L.; Caggianese G.; Barone D.; De Laurentiis M.; Giordano A./titolo:Virtual Reality Rehabilitation Systems for Cancer Survivors: A Narrative Review of the Literature/doi:10.3390%2Fcancers14133163/rivista:Cancers (Basel)/anno:2022/pagina_da:/pagina_a:/intervallo_pagine:/volume:14

Rehabilitation plays a crucial role in cancer care, as the functioning of cancer survivors is frequently compromised by impairments that can result from the disease itself but also from the long-term sequelae of the treatment. Nevertheless, the curre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c570d1c369d0286f14283cdac425d3fc
http://www.cnr.it/prodotto/i/469115

Vanillin prevents doxorubicin-induced apoptosis and oxidative stress in rat H9c2 cardiomyocytes

Autor: Antonio Giordano, Ivana Sirangelo, Clara Iannuzzi, Margherita Borriello, Luigi Sapio, Silvio Naviglio, Daniela Barone, Angela Ragone

Publikováno v: Nutrients
Nutrients, Vol 12, Iss 2317, p 2317 (2020)
Volume 12
Issue 8

Doxorubicin (doxo) is an effective anticancer compound in several tumor types. However, as a consequence of oxidative stress induction and ROS overproduction, its high cardiotoxicity demands urgent attention. Vanillin possesses antioxidant, antiproli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9583671fd449ebae10468ccacf370d6c
http://hdl.handle.net/11591/433265

Antitumoral potential, antioxidant activity and carotenoid content of two Southern Italy tomato cultivars extracts: San Marzano and Corbarino

Autor: Daniela Barone, Letizia Cito, Francesca Pentimalli, Danila Penon, Annamaria Cimini, Antonella Penon, Rocco De Prisco, Paola Indovina, Elisabetta Benedetti, Giuseppina Tommonaro, Agnese Anna Abate, Iris Maria Forte, Antonio Giordano, Barbara Nicolaus

Publikováno v: Journal of cellular physiology
233 (2018): 1266–1277. doi:10.1002/jcp.25995
info:cnr-pdr/source/autori:Barone, Daniela; Cito, Letizia; Tommonaro, Giuseppina; Abate, Agnese Anna; Penon, Danila; De Prisco, Rocco; Penon, Antonella; Forte, Iris Maria; Benedetti, Elisabetta; Cimini, Annamaria; Indovina, Paola; Nicolaus, Barbara; Pentimalli, Francesca; Giordano, Antonio/titolo:Antitumoral Potential, Antioxidant Activity and Carotenoid Content of Two Southern Italy Tomato Cultivars Extracts: San Marzano and Corbarino./doi:10.1002%2Fjcp.25995/rivista:Journal of cellular physiology (Print)/anno:2018/pagina_da:1266/pagina_a:1277/intervallo_pagine:1266–1277/volume:233

Gastric cancer represents a diffuse and aggressive neoplasm, whose mortality index is among the highest in the world. Predisposing factors are E-cadherin mutations, Helicobacter pylori infection and a diet rich in salted and smoked food, with a low i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::960ad5b6aff05c68ab43d46854c1e69e
https://doi.org/10.1002/jcp.25995

Targeted therapy based on p53 reactivation reduces both glioblastoma cell growth and resistance to temozolomide

Autor: Carmelina Antonella Iannuzzi, Donatella Cirillo, Francesca Pentimalli, Daniela Barone, Antonio Giordano, Paola Indovina, Domenico Di Marzo, Iris Maria Forte, Francesca Capone

Glioblastoma (GB) is the most common and aggressive malignant tumor of the central nervous system. Despite current intensive treatment regimens, consisting of surgical resection followed by radiotherapy with concomitant and adjuvant temozolomide (TMZ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d494a81881b1f52f53d76058cad53ccc
http://hdl.handle.net/11365/1129820