Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Daniela B. Munafo"'
Autor:
Barton E. Slatko, Theodore B. Davis, Salvatore Russello, Christine L. Chater, Daniela B. Munafo, Fiona J. Stewart, Andrew F. Gardner, Christine Sumner, Deyra N. Rodriguez, John Morlan, Dominick Sinicropi, Kunbin Qu, Bradley W. Langhorst, Eileen T. Dimalanta
Publikováno v:
Current Protocols in Molecular Biology
Ribosomal RNAs (rRNAs) are extremely abundant, often constituting 80% to 90% of total RNA. Since rRNA sequences are often not of interest in genomic RNA sequencing experiments, rRNAs can be removed from the sample before the library preparation step,
Autor:
Miguel C. Seabra, Tanya Tolmachova, Hong Hong, Sergio D. Catz, Beverly A. Ellis, Agnieszka A. Brzezinska, Daniela B. Munafo, Jennifer L. Johnson
Publikováno v:
Traffic. 11:533-547
Neutrophils rely on exocytosis to mobilize receptors and adhesion molecules and to release microbicidal factors. This process should be strictly regulated because uncontrolled release of toxic proteins would be injurious to the host. In vivo studies
Autor:
Sergio D. Catz, Agnieszka A. Brzezinska, Beverly A. Ellis, Jennifer L. Johnson, Malcolm R. Wood, Daniela B. Munafo
Publikováno v:
Journal of Innate Immunity. 1:527-542
Neutrophils kill bacteria on extracellular complexes of DNA fibers and bactericidal proteins known as neutrophil extracellular traps (NETs). The NET composition and the bactericidal mechanisms they use are not fully understood. Here, we show that tre
Autor:
Sergio D. Catz, Daniela B. Munafo, Jennifer L. Johnson, Beverly A. Ellis, Agnieszka A. Brzezinska, Sandrine Pacquelet, William S. Lane
Publikováno v:
Biochemical Journal. 403:451-461
Exposure of neutrophils to LPS (lipopolysaccharide) triggers their oxidative response. However, the relationship between the signalling downstream of TLR4 (Toll-like receptor 4) after LPS stimulation and the activation of the oxidase remains elusive.
Autor:
Beverly A. Ellis, Daniela B. Munafo, Jennifer L. Johnson, Sergio D. Catz, Sophie Rutschmann, Bruce Beutler
Publikováno v:
Biochemical Journal. 402:229-239
Neutrophils kill micro-organisms using microbicidal products that they release into the phagosome or into the extracellular space. The secretory machinery utilized by neutrophils is poorly characterized. We show that the small GTPase Rab27a is an ess
Autor:
Keerthana Krishnan, Vaishnavi Panchapakesa, Lynne Apone, Theodore B. Davis, Joanna Bybee, Laurie Mazzola, Eileen T. Dimalanta, Deyra N. Rodriguez, Daniela B. Munafo, Fiona J. Stewart, Karen Duggan, Christine Sumner, Bradley W. Langhorst, Timur Shtatland, Pingfang Liu, Christine Rozzi, Mehmet Karaca, Danielle Rivizzigno, Erbay Yigit
Publikováno v:
Cancer Research. 77:5406-5406
RNA-seq has become the most popular method for transcriptome analysis and is widely used to study gene expression, detect mutations, fusion transcripts, alternative splicing, and post-transcriptional modifications. It is becoming the method of choice
Autor:
Theodore B. Davis, Erbay Yigit, Lynne Apone, Christine Sumner, Gregory J. S. Lohman, Daniela B. Munafo, Fiona J. Stewart, Thomas C. Evans, Nicole M. Nichols, Bradley W. Langhorst, Eileen T. Dimalanta, Pingfang Liu, Eric J. Cantor
Publikováno v:
BMC Proceedings, Vol 6, Iss Suppl 6, p P26 (2012)
BMC Proceedings
BMC Proceedings
Next Generation Sequencing (NGS) has significantly impacted human genetics, enabling a comprehensive characterization of the human genome as well as a better understanding of many genomic abnormalities. By delivering massive DNA sequences at unpreced
Autor:
Christine Sumner, Lynne Apone, Theodore B. Davis, Brad Langhorst, Erbay Yigit, Daniela B. Munafo, Fiona J. Stewart, Eileen T. Dimalanta, Ping Liu, Landon Merrill
Publikováno v:
BMC Proceedings, Vol 6, Iss Suppl 6, p P30 (2012)
BMC Proceedings
BMC Proceedings
Background Standard RNA sequencing approaches generally require double-stranded cDNA synthesis, which erases RNA strand information. Synthesis of a randomly primed double-stranded cDNA followed by addition of adaptors for next-generation sequencing l
Autor:
G. Brett Robb, Daniela B. Munafo
Publikováno v:
RNA (New York, N.Y.). 16(12)
Small regulatory RNA repertoires in biological samples are heterogeneous mixtures that may include species arising from varied biosynthetic pathways and modification events. Small RNA profiling and discovery approaches ought to capture molecules in a
Autor:
Beverly A. Ellis, Jennifer L. Johnson, Sergio D. Catz, Daniela B. Munafo, Agnieszka A. Brzezinska
Publikováno v:
Immunology. 127(3)
Lipopolysaccharide (LPS) stimulates exocytosis in neutrophils. The signalling molecules involved in the regulation of this mechanism are currently unknown. Using neutrophils from interleukin-1-receptor-associated kinase (IRAK)-4- and Toll/IL-1 recept