Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Daniela B Divlianska"'
Autor:
Danielle McAnally, Khandaker Siddiquee, Ahmed Gomaa, Andras Szabo, Stefan Vasile, Patrick R Maloney, Daniela B Divlianska, Satyamaheshwar Peddibhotla, Camilo J Morfa, Paul Hershberger, Rebecca Falter, Robert Williamson, David B Terry, Rafal Farjo, Anthony B Pinkerton, Xiaping Qi, Judith Quigley, Michael E Boulton, Maria B Grant, Layton H Smith
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0202436 (2018)
Neovascularization is the pathological driver of blinding eye diseases such as retinopathy of prematurity, proliferative diabetic retinopathy, and wet age-related macular degeneration. The loss of vision resulting from these diseases significantly im
Externí odkaz:
https://doaj.org/article/2711b08fb0d24cb796c83d996b6a93ad
Autor:
Zongyang Lv, Lingmin Yuan, James H. Atkison, Katelyn M. Williams, Ramir Vega, E. Hampton Sessions, Daniela B. Divlianska, Christopher Davies, Yuan Chen, Shaun K. Olsen
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Ubiquitin and ubiquitin-like modifiers such as SUMO play important roles in several cellular pathways that can become deregulated in cancer. Here the authors describe the structural basis for inhibition of SUMO E1 ligase by the small molecule COH000.
Externí odkaz:
https://doaj.org/article/790d42b1a88b44e08307e39d6b2a360c
Autor:
Paul M. Hershberger, Satyamaheshwar Peddibhotla, E. Hampton Sessions, Daniela B. Divlianska, Ricardo G. Correa, Anthony B. Pinkerton, John C. Reed, Gregory P. Roth
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 9, Iss 1, Pp 900-907 (2013)
Activation of nuclear factor-kappa B (NF-κB) and related upstream signal transduction pathways have long been associated with the pathogenesis of a variety of inflammatory diseases and has recently been implicated in the onset of cancer. This report
Externí odkaz:
https://doaj.org/article/789311d353004329b484f281ae36bb75
Autor:
Satyamaheshwar Peddibhotla, R. Jason Kirby, Siobhan Malany, E. Hampton Sessions, Eliot Sugarman, Camilo J. Morfa, Layton H. Smith, Patrick R. Maloney, David B. Terry, Daniela B. Divlianska, Anthony B. Pinkerton, Paul Hershberger
Publikováno v:
Bioorg Med Chem Lett
The chemokine system plays an important role in mediating a proinflammatory microenvironment for tumor growth in hepatocellular carcinoma (HCC). The CXCR6 receptor and its natural ligand CXCL16 are expressed at high levels in HCC cell lines and tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62936acf1e6bf674557060824dcd7804
https://pubmed.ncbi.nlm.nih.gov/31882297
https://pubmed.ncbi.nlm.nih.gov/31882297
Autor:
Nidhi Kapoor, Daniela B. Divlianska, E. Hampton Sessions, Stephen J. Gardell, Jeffrey A. Culver, Chris Petucci
Publikováno v:
Methods in Molecular Biology ISBN: 9781493994878
Pyridine nucleotides which include NAD+, NADH, NADP, and NADPH play vital roles in many different biological processes. These metabolites can be accurately quantified in a wide variety of biological samples using LC-MS/MS. The quality and precision o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a23d10cd0d842c4c35fefb34ae017ba
https://doi.org/10.1007/978-1-4939-9488-5_7
https://doi.org/10.1007/978-1-4939-9488-5_7
Autor:
Christopher Davies, Daniela B. Divlianska, Lingmin Yuan, Ramir Vega, James H. Atkison, E.H. Sessions, Yuan Chen, Zongyang Lv, K.M. Williams, Shaun K. Olsen
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
E1 enzymes activate ubiquitin (Ub) and ubiquitin-like modifiers (Ubls) in the first step of Ub/Ubl conjugation cascades and represent potential targets for therapeutic intervention in cancer and other life-threatening diseases. Here, we report the cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e02c335eea97d74088a01482a55dfce
https://doi.org/10.1038/s41467-018-07015-1
https://doi.org/10.1038/s41467-018-07015-1
Autor:
Thomas D.Y. Chung, Sharon A. Colayco, Baozong Li, Li Du, Jianghai Wang, Yi-Jia Li, Ramir Vega, Daniela B. Divlianska, Grace Aldana-Masangkay, Ekaterina V. Bobkova, Terry D. Lee, Yunan Miao, Marwan Fakih, Eduard Sergienko, Yuan Chen, S. Xiaohu Ouyang, Eric R. Samuels
Publikováno v:
Cell chemical biology. 26(2)
Summary Ubiquitin-like (Ubl) post-translational modifications are potential targets for therapeutics. However, the only known mechanism for inhibiting a Ubl-activating enzyme is through targeting its ATP-binding site. Here we identify an allosteric i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6262e81209415b5aea89a530f02dd0d
https://pubmed.ncbi.nlm.nih.gov/30794786
https://pubmed.ncbi.nlm.nih.gov/30794786
Autor:
Anthony B. Pinkerton, Maria B. Grant, Patrick R. Maloney, Andras Szabo, Danielle McAnally, Satyamaheshwar Peddibhotla, Xiaping Qi, Rafal Farjo, Robert Williamson, Khandaker Siddiquee, Camilo J. Morfa, Judith Quigley, Michael E. Boulton, Paul Hershberger, Ahmed Gomaa, Layton H. Smith, Rebecca Falter, Daniela B. Divlianska, David B. Terry, Stefan Vasile
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0202436 (2018)
Neovascularization is the pathological driver of blinding eye diseases such as retinopathy of prematurity, proliferative diabetic retinopathy, and wet age-related macular degeneration. The loss of vision resulting from these diseases significantly im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acbafb8c0a9fad2a3628c142439537fd
https://pubmed.ncbi.nlm.nih.gov/30208056
https://pubmed.ncbi.nlm.nih.gov/30208056
Autor:
Camilo J. Morfa, Ada Koo, Paul Hershberger, Nadezda Bryan, Kanupriya Whig, Becky Hood, Siobhan Malany, Satayamaheshwar Peddibhotla, E. Hampton Sessions, Patrick R. Maloney, Layton H. Smith, R. Jason Kirby, Kevin Nguyen, Daniela B. Divlianska
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 364(1)
Oxidative injury to cardiomyocytes plays a critical role in cardiac pathogenesis following myocardial infarction. Transplantation of stem cell-derived cardiomyocytes has recently progressed as a novel treatment to repair damaged cardiac tissue but it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::826892109a0c0c9cf0ccc8dd33b5580e
https://pubmed.ncbi.nlm.nih.gov/29335361
https://pubmed.ncbi.nlm.nih.gov/29335361
Autor:
David J. Newman, Daniela B. Divlianska, Amy E. Wright, Christine E. Salomon, Sylvia Kim, Paul Kung, Barry R. O'Keefe, Susan G. Brown, Thomas R. Hoye, Mehrak Kiankarimi, Dayong Zhai, John C. Reed, Michael A. Walters, Paul Diaz, Shana Morshedian, Andrew R. Michel, Subhashree Francis, Christian Andrew Hassig, Kate Welsh, Harneet Kaur, Fu Yue Zeng, Gunda I. Georg, Beeraiah Baire, Gregory P. Roth, Ying Su, Yudi Rusman
Publikováno v:
SLAS Discovery. 19:1201-1211
Antiapoptotic Bcl-2 family proteins are validated cancer targets composed of six related proteins. From a drug discovery perspective, these are challenging targets that exert their cellular functions through protein-protein interactions (PPIs). Altho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fccdeeb6b0346716bae36798d5495c2e
https://doi.org/10.1177/1087057114536227
https://doi.org/10.1177/1087057114536227